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- Mitani, Yuji; Satake, Kazuhiro; Tsukamoto, Megumi; Nakamura, Ichiro; Kadioglu, Onat; Teruya, Toshiaki; Yonezawa, Takayuki; Cha, Byung-Yoon; Efferth, Thomas; Woo, Je-Tae; Nakagawa, Hiroshi
- Phytomedicine 2018 v.51 pp. 112-119
- Magnolia biondii, etc ; ABC transporters; adenosinetriphosphatase; antineoplastic agents; buds; computer simulation; drug resistance; enzyme activity; enzyme kinetics; humans; ingredients; lignans; nose; pharmacokinetics; rhinitis; sinusitis; verapamil; Show all 17 Subjects
- ... Epimagnolin A is an ingredient of the Chinese crude drug Shin-i, derived from the dried flower buds of Magnolia fargesii and Magnolia flos, which has been traditionally used for the treatment of allergic rhinitis and nasal congestion, empyema, and sinusitis. The pharmacokinetic activity of epimagnolin A remains to be evaluated.In this study, we examined the possible interactions of epimagnolin A w ...