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- Bi, Jing; Tsai, Nien-Pei; Lu, Hsin-Yi; Loh, Horace H.; Wei, Li-Na
- Proceedings of the National Academy of Sciences of the United States of America 2007 v.104 no.34 pp. 13810-13815
- axonal transport; axons; drugs; ganglia; messenger RNA; microtubules; screening; translation (genetics); yeasts
- ... mRNA of κ opioid receptor (KOR) can be transported to nerve fibers, including axons of dorsal root ganglia (DRG), and can be locally translated. Yeast three-hybrid screening identifies Copb1 as a kor mRNA-associated protein that form complexes with endogenous kor mRNA, which are colocalized in the soma and axons of DRG neurons. Axonal transport of kor mRNA is demonstrated, directly, by observing m ...
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