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- Starai, Vincent J.; Jun, Youngsoo; Wickner, William
- Proceedings of the National Academy of Sciences of the United States of America 2007 v.104 no.34 pp. 13551-13558
- guanosinetriphosphatase; lipids; membrane fusion; protein transport; receptors; vacuoles; yeasts
- ... Although concentrated soluble N-ethylmaleimide-sensitive factor attachment protein receptors (SNAREs) drive liposome fusion and lysis, the fusion of intracellular membranes also requires Rab GTPases, Rab effectors, SM proteins, and specific regulatory lipids and is accompanied by little or no lysis. To rationalize these findings, we generated yeast strains that overexpress all four vacuolar SNAREs ...
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