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- Silo-Suh, L.; Suh, S.J.; Sokol, P.A.; Ohman, D.E.
- Proceedings of the National Academy of Sciences of the United States of America 2002 v.99 no.24 pp. 15699-15704
- alginates, etc ; Pseudomonas aeruginosa; strains; isolation; cystic fibrosis; humans; seedlings; Medicago sativa; carbohydrate metabolism; binding proteins; pathogenesis; virulence; lungs; rats; Show all 14 Subjects
- ... A sensitive plant infection model was developed to identify virulence factors in nontypeable, alginate overproducing (mucoid) Pseudomonas aeruginosa strains isolated from cystic fibrosis (CF) patients with chronic pulmonary disease. Nontypeable strains with defects in lipopolysaccharide O-side chains are common to CF and often exhibit low virulence in animal models of infection. However, 1,000 suc ...
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