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- Inda, María Eugenia, et al. Show all 6 Authors
- Proceedings of the National Academy of Sciences of the United States of America 2014 v.111 no.9 pp. 3579-3584
- Bacillus subtilis; active sites; bacteria; cytoplasm; hydrophilicity; phospholipids; temperature; unsaturated fatty acids
- ... The thermosensor DesK is a multipass transmembrane histidine-kinase that allows the bacterium Bacillus subtilis to adjust the levels of unsaturated fatty acids required to optimize membrane lipid fluidity. The cytoplasmic catalytic domain of DesK behaves like a kinase at low temperature and like a phosphatase at high temperature. Temperature sensing involves a built-in instability caused by a grou ...
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