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- Rajaram, Murugesan V. S.; Ni, Bin; Morris, Jessica D.; Brooks, Michelle N.; Carlson, Tracy K.; Bakthavachalu, Baskar; Schoenberg, Daniel R.; Torrelles, Jordi B.; Schlesinger, Larry S.
- Proceedings of the National Academy of Sciences of the United States of America 2011 v.108 no.42 pp. 17408-17413
- immune response, etc ; 3' untranslated regions; Mycobacterium tuberculosis; biosynthesis; cell walls; half life; humans; macrophages; microRNA; mitogen-activated protein kinase; mitogen-activated protein kinase kinase; phosphorylation; receptors; tumor necrosis factors; virulence; Show all 15 Subjects
- ... Contact of Mycobacterium tuberculosis (M.tb) with the immune system requires interactions between microbial surface molecules and host pattern recognition receptors. Major M.tb-exposed cell envelope molecules, such as lipomannan (LM), contain subtle structural variations that affect the nature of the immune response. Here we show that LM from virulent M.tb (TB-LM), but not from avirulent Myocobact ...
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