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- Fry, J.D.; Keightley, P.D.; Heinsohn, S.L.; Nuzhdin, S.V.
- Proceedings of the National Academy of Sciences of the United States of America 1999 v.96 no.2 pp. 574-579
- viability, etc ; Drosophila melanogaster; autosomes; genotype-environment interaction; analysis of variance; mutation; Show all 6 Subjects
- ... The genomic rate and distribution of effects of deleterious mutations are important parameters in evolutionary theory. The most detailed information comes from the work of Mukai and Ohnishi, who allowed mutations to accumulate on Drosophila melanogaster second chromosomes, shielded from selection and recombination by being maintained heterozygous in males. Averaged over studies, the estimated rate ...