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- Boussinesq, Michel, et al. Show all 9 Authors
- Proceedings of the National Academy of Sciences of the United States of America 2009 v.106 no.39 pp. 16716-16721
- Onchocerca volvulus; drug resistance; drugs; genetic markers; humans; ivermectin; mathematical models; microfilariae; onchocerciasis; parasite load; parasites; phenotype; public health; villages; Ghana
- ... Identification of drug resistance before it becomes a public health concern requires a clear distinction between what constitutes a normal and a suboptimal treatment response. A novel method of analyzing drug efficacy studies in human helminthiases is proposed and used to investigate recent claims of atypical responses to ivermectin in the treatment of River Blindness. The variability in the rate ...
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