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- Grundman, Michael; Delaney, Patrick
- Proceedings of the Nutrition Society 2002 v.61 no.2 pp. 191-202
- Alzheimer disease; Ginkgo biloba; antioxidant activity; antioxidants; ascorbic acid; beta-carotene; clinical trials; cognition; creatine; curcumin; disease course; elderly; energy; epidemiological studies; free radicals; industry; inflammation; lipids; lipoic acid; melatonin; nucleic acids; oxidative stress; patients; proteins; ubiquinones; vitamin E
- ... Oxidative damage is present within the brains of patients with Alzheimer's disease (AD), and is observed within every class of biomolecule, including nucleic acids, proteins, lipids and carbohydrates. Oxidative injury may develop secondary to excessive oxidative stress resulting from β-amyloid-induced free radicals, mitochondrial abnormalities, inadequate energy supply, inflammation or altered ant ...
- Meydani, Mohsen
- Proceedings of the Nutrition Society 2002 v.61 no.2 pp. 165-171
- Alzheimer disease; angiogenesis; antioxidant activity; antioxidants; cardiovascular diseases; cell adhesion; chronic diseases; elderly; endothelial cells; energy; exercise; fruit consumption; immune response; intercellular junctions; interleukin-8; lifestyle; longevity; malnutrition; mice; middle-aged adults; morbidity; mortality; neoplasms; nutritional intervention; nutritional status; oxidative stress; phytochemicals; polyphenols; risk; socioeconomic status; vegetables; vitamin E
- ... Aging is a complex biological process, which usually is accompanied by changes in socioeconomic status, which may have a great impact on the physical and nutritional status of the elderly. Decreased food intake and a sedentary lifestyle in the growing numbers of the elderly increase their risk for malnutrition, decline of bodily functions and developing chronic diseases. Oxidative stress is believ ...