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You searched for: Journal name Process biochemistry Remove constraint Journal name: Process biochemistry Publication year rev 7978-2022 Remove constraint Publication year rev: 7978-2022 Source 2022 v.118 Remove constraint Source: 2022 v.118
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1. An empirical review on the risk factors, therapeutic strategies and materials at nanoscale for the treatment of oral malignancies

Author:
Parveez Ahamed Abdul Azees; Suganthy Natarajan; Bennett T. Amaechi; Nooruddin Thajuddin; Vinay B. Raghavendra; Kathirvel Brindhadevi; Arivalagan Pugazhendhi; Tran Nhat Phuong
Source:
Process biochemistry 2022 v.118 pp. 283-293
ISSN:
1359-5113
Subject:
biochemistry; mortality; mouth neoplasms; nanomedicine; oral health; surgery
Abstract:
... Oral health of an individual is a key factor in initiation of oral cancer. Oral cancer can be classified into five stages and involves several risk factors. Novel and safe therapeutic procedures are necessary for this type of aggressive cancer with high mortality and poor diagnosis. Surgery and radiation are common procedures for treatment of oral cancer. Nanomedicine is a recent avenue in oncolog ...
DOI:
10.1016/j.procbio.2022.04.013

2. Antibacterial activity potential of leaf extracts of Blepharis maderaspatensis and Ziziphus oenoplia against antibiotics resistant Pseudomonas strains isolated from pus specimens

Author:
Chokkalingam Mohanasundari; Sorimuthu Anbalagan; Kesavan Srinivasan; Mathiyazhagan Narayanan; Mythili Saravanan; Sulaiman Ali Alharbi; Saleh H. Salmen; Tran Cam Nhung; Arivalagan Pugazhendhi
Source:
Process biochemistry 2022 v.118 pp. 24-31
ISSN:
1359-5113
Subject:
Blepharis; Enterococcus; Klebsiella; Micrococcus; Staphylococcus; Ziziphus; antibacterial properties; antibiotic resistance; drug therapy; leaves; methanol; solvents
Abstract:
... Knowing the antibiotic resistance profile of pathogenic bacteria is essential to finding an appropriate remedy for these issues by sourcing antibacterial agents from plants. The present study exposes the bactericidal potential of different leaf extracts of Blepharis maderaspatensis and Ziziphus oenoplia against multi drug resistant bacterial strains enumerated from pus specimens at a secondary car ...
DOI:
10.1016/j.procbio.2022.04.008

3. Aqueous two-phase extraction of polysaccharides from Selaginella doederleinii and their bioactivity study

Author:
Gang Li; Xiankui Ma; Yongmei Jiang; Weiwei Li; Yongling Wang; Li Liu; Chengxin Sun; Shiji Xiao; Jie Lan; Juxiang Kuang; Gang Wang
Source:
Process biochemistry 2022 v.118 pp. 274-282
ISSN:
1359-5113
Subject:
Selaginella doederleinii; antineoplastic activity; antioxidant activity; antioxidants; ethanol; liquids; polysaccharides; salt concentration; thermogravimetry; ultrasonics
Abstract:
... In this study, the ethanol/salt aqueous two-phase system was firstly used to extract Selaginella doederleinii polysaccharides (SDP). Through single factor and response surface analysis, the best extraction conditions were as follows: extraction time of 40 min, ultrasonic power of 280 W, ethanol concentration of 35%, inorganic salt concentration of 0.22 g/mL, and liquid/solid ratio of 25 mL/g with ...
DOI:
10.1016/j.procbio.2022.04.024

4. Ascorbic acid biosensing methods: A review

Author:
Meghna Malik; Vinay Narwal; C.S. Pundir
Source:
Process biochemistry 2022 v.118 pp. 11-23
ISSN:
1359-5113
Subject:
ambient temperature; ascorbic acid; biosensors; blood serum; central nervous system; commercialization; detection limit; diabetes; liver diseases; metabolism; neurotransmitters; oxidative stress; pH; people; urine
Abstract:
... Ascorbic acid has a significant regulatory effect on neurotransmitters and enzymes in the central nervous system. In apparently healthy people, the reference range for ascorbic acid is 0.6–2 mg/dL. The variable concentration of ascorbic acid within biology fluids was found in clinical investigations to be a metric for assessing the exact amount of oxidative stress in the body's metabolism. The ris ...
DOI:
10.1016/j.procbio.2022.03.028

5. Discovery of a novel acrylic acid formation pathway in Gluconobacter oxydans and its application in biosynthesis of acrylic acid from glycerol

Author:
Li Zhao; Jiawei Zhu; Kum-Song Ro; Jingli Xie; Dongzhi Wei
Source:
Process biochemistry 2022 v.118 pp. 182-189
ISSN:
1359-5113
Subject:
Escherichia coli; Gluconobacter oxydans; Klebsiella pneumoniae; acrolein; acrylic acid; alcohol dehydrogenase; aldehyde dehydrogenase; biochemical pathways; biosynthesis; gene deletion; gene expression; glycerol; isozymes; metabolites
Abstract:
... This study revealed a novel metabolic pathway of acrylic acid in Gluconobacter oxydans. First, the intermediate metabolite acrolein was confirmed by HPLC and GC-MS analyses. Then, the enzymes involved were identified based on mRNA expression analysis and gene deletion studies. This novel pathway includes three successive reactions: i) an alcohol dehydrogenase catalyzes 1,3-propanediol to 3-hydroxy ...
DOI:
10.1016/j.procbio.2022.04.027

6. High efficient crosslinking of gelatin and preparation of its excellent flexible composite film using deep eutectic solvent

Author:
Ting Wu; Rui Dai; Zhihua Shan; Hui Chen; Meng Wai Woo; Jie Yi
Source:
Process biochemistry 2022 v.118 pp. 32-40
ISSN:
1359-5113
Subject:
ambient temperature; brittleness; composite films; crosslinking; gelatin; gelation; polyvinyl alcohol; sodium acetate; solubility; solvents; urea
Abstract:
... To overcome the gelation of gelatin at low temperatures, solve the brittleness of gelatin-based films and improve the reaction efficiency between the components, a facile design strategy is proposed for preparing gelatin/polyvinyl alcohol composite films (Gel-PVAs) with excellent flexibility. During the preparation process, sodium acetate trihydrate/urea deep eutectic solvent (SAT/U-DES) was intro ...
DOI:
10.1016/j.procbio.2022.04.014

7. Immobilization of papain on nitrogen-doped graphene quantum dots improves the enzymatic properties and makes it a biosensor for cystatin C

Author:
Farzaneh Mirzaei; Hassan Valizadeh; Mohammad Pazhang
Source:
Process biochemistry 2022 v.118 pp. 307-316
ISSN:
1359-5113
Subject:
biosensors; fluorometry; glutaraldehyde; graphene; papain
Abstract:
... In recent years enzymes had many applications, such as catalysts in organic synthesis and producing biosensors. In this study, nitrogen-doped graphene quantum dots (NGQDs) were functionalized with glutaraldehyde (NGQD-Glu) and used as a support for the immobilization of papain (NGQD-Glu-Papain). Immobilization of papain on NGQDs has considerably improved papain stability. So, with incubation of th ...
DOI:
10.1016/j.procbio.2022.04.026

8. Microwave-mediated synthesis of iron oxide nanoparticles: Photocatalytic, antimicrobial and their cytotoxicity assessment

Author:
Abdurahman Hajinur Hirad; Siddique Akber Ansari; Mohamed Abdellatif Eltayeb Ali; Mohamed Ali Egeh
Source:
Process biochemistry 2022 v.118 pp. 205-214
ISSN:
1359-5113
Subject:
Fourier transform infrared spectroscopy; Ocimum tenuiflorum; X-ray diffraction; antimicrobial properties; biocompatibility; cytotoxicity; dose response; energy-dispersive X-ray analysis; iron oxides; leaf extracts; lung neoplasms; macrophages; methylene blue; microwave radiation; photocatalysis; transmission electron microscopy; zeta potential
Abstract:
... In the current study, iron oxide nanoparticles (IONPs) were synthesized using Ocimum tenuiflorum (OT). The OT leaf extract reduces the ferrous ions to IONPs under microwave irradiation. The biologically synthesized nanoparticles were characterized by Ultraviolet visible (UV–vis) spectroscopy, Fourier transform infrared spectroscopy (FTIR), X-ray diffraction (XRD) and Energy Dispersive X-ray (EDX) ...
DOI:
10.1016/j.procbio.2022.04.022

9. Multi target interactions of essential oil nanoemulsion of Cinnamomum travancoricum against diabetes mellitus via in vitro, in vivo and in silico approaches

Author:
Venkatraman Sriramavaratharajan; David Raj Chellappan; Shanmugam Karthi; Mathialagan Ilamathi; Ramar Murugan
Source:
Process biochemistry 2022 v.118 pp. 190-204
ISSN:
1359-5113
Subject:
Cinnamomum; alpha-amylase; blood glucose; blood serum; computer simulation; diabetes mellitus; essential oils; glucose; glycemic effect; insulin receptors; insulin secretion; leaves; linalool; nanoemulsions; safrole; spathulenol; triacylglycerols; India
Abstract:
... This study reports antidiabetic activity of leaf essential oil (EO) of Cinnamomum travancoricum from the Western Ghats, India via in vitro , in vivo and in silico methods. EO was characterized by GC-MS and GC-FID. Essential oil nanoemulsions (EN) were prepared and characterized. Antidiabetic potential was evaluated through in vitro assays namely, α-amylase and α-glucosidase inhibition, glucose upt ...
DOI:
10.1016/j.procbio.2022.04.031

10. Polyphenolic composition and antimicrobial activity of extracts obtained from grape processing by-products: Between green biotechnology and nutraceutical

Author:
Paola Angelini; Giancarlo Angeles Flores; Alessandro Piccirilli; Roberto Venanzoni; Alessandra Acquaviva; Simonetta Cristina Di Simone; Maria Loreta Libero; Bruno Tirillini; Gokhan Zengin; Annalisa Chiavaroli; Lucia Recinella; Sheila Leone; Luigi Brunetti; Giustino Orlando; Luigi Menghini; Claudio Ferrante
Source:
Process biochemistry 2022 v.118 pp. 84-91
ISSN:
1359-5113
Subject:
Arthroderma; Trichophyton rubrum; Vitis vinifera; antimicrobial properties; biomass; biotechnology; byproducts; catechin; cultivars; dietary supplements; fungi; grape pomace; grapes; health promotion; juices; metabolism; phenols; wine industry; wines
Abstract:
... Vitis vinifera (grape) is a multiuse crop rich in biomolecules with recognized health-promoting effects. In the wine-making industry, pomace is the main by-product, representing up to 20% of the whole biomass. However, the pomace and juice deriving from the pressing may represent innovative raw materials, and in the present study, the aim was to compare phenolic composition and biological activiti ...
DOI:
10.1016/j.procbio.2022.04.019

11. Production, extraction and characterization of a serine protease with fibrinolytic, fibrinogenolytic and thrombolytic activity obtained by Paenibacillus graminis

Author:
Milena Tereza Torres do Couto; Aníbia Vicente da Silva; Renata Vitória Da Silva Sobral; Cláudio Henrique Rodrigues; Márcia Nieves Carneiro da Cunha; Ana Cristina Lima Leite; Márcia do Vale Barreto Figueiredo; José de Paula Oliveira; Romero Marcos Pedrosa Brandão Costa; Amanda Emmanuelle Sales Conniff; Ana Lúcia Figueiredo Porto; Thiago Pajeú Nascimento
Source:
Process biochemistry 2022 v.118 pp. 335-345
ISSN:
1359-5113
Subject:
Gliricidia sepium; Paenibacillus; calcium; cattle; endosperm; enzyme activity; fibrinogen; humans; pH; serine proteinases; submerged fermentation; thrombosis
Abstract:
... This study provides optimized parameters for producing and purifying a microbial serine protease by Paenibacillus graminis in submerged fermentation and the innovative use of endosperm of Gliricidia sepium as substrate. Biphasic aqueous systems were the method of choice for the partial purification of this protease. After extracting the enzyme, its biochemical characterization and fibrinolytic, fi ...
DOI:
10.1016/j.procbio.2022.05.005

12. Prolyl aminopeptidases: Reclassification, properties, production and industrial applications

Author:
Zixing Dong; Shuangshuang Yang; Zhengtian Zhang; Cunduo Tang; Yunchao Kan; Lunguang Yao
Source:
Process biochemistry 2022 v.118 pp. 121-132
ISSN:
1359-5113
Subject:
aminolysis; debittering; dietary supplements; fermentation; peptides; phylogeny; proline; prolyl aminopeptidase; salt tolerance; serine; taxonomic revisions
Abstract:
... Prolyl aminopeptidase (PAP, EC 3.4.11.5), belonging to S33 family within the SC clan of serine peptidases, is an exopeptidase that specifically removes proline from the N-terminus of peptides or proteins. Its distinct properties, such as debittering activity, aminolysis reaction and salt tolerance, make it find wide applications in food, nutraceutical, medical diagnosis and other fields. However, ...
DOI:
10.1016/j.procbio.2022.04.025

13. The protective effect of C3G against Pb-induced learning and memory impairments through cAMP-PKA-CREB signaling pathway in rat hippocampus

Author:
Yao Chen; Guanghua Mao; Zhenghongri Zhang; Ting Zhao; Weiwei Feng; Liuqing Yang; Xiangyang Wu
Source:
Process biochemistry 2022 v.118 pp. 381-393
ISSN:
1359-5113
Subject:
anthocyanins; biomarkers; blood; calcium; cognition; cognitive disorders; glutathione peroxidase; hippocampus; malondialdehyde; memory; nerve tissue; neuroprotective effect; neurotoxicity; neurotransmitters; oxidative stress; protein kinases; rats; superoxide dismutase
Abstract:
... Cyanidin-3-O-glucoside (C3G) is the main kind of anthocyanins that has been reported to possess neuroprotective potentials. In this study, the protection effects of C3G on Pb-induced neurotoxicity and underlying mechanisms were demonstrated. Integrated biomarker responses (IBR) were employed to comprehensively evaluate the neuroprotection of C3G. Results showed that C3G apparently ameliorated the ...
DOI:
10.1016/j.procbio.2022.05.007

14. Transcriptomes analysis of Pichia kudriavzevii UniMAP 3–1 in response to acetic acid supplementation in glucose and xylose medium at elevated fermentation temperature

Author:
Khadijah Hanim Abdul Rahman; Nazalan Najimudin; Ku Syahidah Ku Ismail
Source:
Process biochemistry 2022 v.118 pp. 41-51
ISSN:
1359-5113
Subject:
Pichia kudriavzevii; RNA; acetic acid; amino acid metabolism; bioethanol; ethanol production; fermentation; gene expression regulation; glucose; glycolysis; lignocellulose; lipid metabolism; stress tolerance; temperature; transcriptome; transcriptomics; xylose; yeasts
Abstract:
... The yeast Pichia kudriavzevii is gaining attention as a potential lignocellulosic bioethanol producer due to its multiple stress tolerance characteristics. RNA sequencing was performed to analyze the transcriptomics profiling of an isolated strain, Pichia kudriavzevii UniMAP 3–1 in response to acetic acid supplementation at 40ºC in individual glucose and xylose medium. Acetic acid was found to be ...
DOI:
10.1016/j.procbio.2022.03.027

15. An updated comprehensive review of advances on structural features, catalytic mechanisms, modification methods and applications of chitosanases

Author:
Yinxiao Xu; Li Li; Shengsheng Cao; Benwei Zhu; Zhong Yao
Source:
Process biochemistry 2022 v.118 pp. 263-273
ISSN:
1359-5113
Subject:
antioxidants; biological control; chitosan; disease resistance; gene transfer; glucosamine; glycosidases; medicine; oligosaccharides; pests; protoplasts
Abstract:
... Chitosan is a kind of linear alkaline polysaccharide, which consists of N-acetyl-D-glucosamine units and D-glucosamine units. Both chitosan and its degradation products (chitosan oligosaccharides) possess versatile biological activities such as antitumor, antioxidant, antimicrobial, and anti-inflammatory activities. Therefore, chitosan and its chitosan oligosaccharides held great potential in food ...
DOI:
10.1016/j.procbio.2022.05.001

16. Bacterial exopolysaccharides-mediated synthesis of polymeric silver nanodots with remarkable wound healing properties

Author:
Nisha Sharma; Vasvani Rahul Ashil; Vinod Kumar; Dattatraya Dinkar Gore; Inder Pal Singh; Kulbhushan Tikoo
Source:
Process biochemistry 2022 v.118 pp. 346-359
ISSN:
1359-5113
Subject:
Lactobacillus gasseri; arabinose; cell viability; cyanides; dose response; exopolysaccharides; free radicals; gel chromatography; glucose; hydroxyl radicals; maltose; mannose; molecular weight; nanosilver; polymers; silver; therapeutics
Abstract:
... Bacterial exopolysaccharides have recently gained much attention due to their widespread biological and therapeutic actions. Here, we describe the process of obtaining exopolysaccharides (EPS) of Lactobacillus gasseri and its characterization using various analytical techniques. Results from gel permeation chromatography and GC-MS analysis revealed that EPS had an average molecular weight of 1.29  ...
DOI:
10.1016/j.procbio.2022.04.029

17. Bone formation and bone repair: The roles and crosstalk of osteoinductive signaling pathways

Author:
Zhan Jing; Zhihui Liang; Liang Yang; Wenyan Du; Tao Yu; Huayu Tang; Changde Li; Wei Wei
Source:
Process biochemistry 2022 v.118 pp. 252-262
ISSN:
1359-5113
Subject:
bone formation; bone fractures; fibroblasts; homeostasis; mammals; phosphatidylinositol 3-kinase; rapamycin; therapeutics; transcription factors
Abstract:
... Until today, significant progress has been achieved in understanding bone homeostasis. Studies have shown that several signaling pathways are involved in embryonic bone formation, as well as bone fracture healing. Some of these signaling pathways have direct osteoinductive effects, which help the bone repair process. Understanding the crosstalk between osteoinductive molecular pathways in bone for ...
DOI:
10.1016/j.procbio.2022.04.033

18. Characterization of the facultative anaerobic Pseudomonas stutzeri strain HK13 to achieve efficient nitrate and nitrite removal

Author:
Lei Ding; Bing Han; Jianmin Zhou
Source:
Process biochemistry 2022 v.118 pp. 236-242
ISSN:
1359-5113
Subject:
Pseudomonas stutzeri; activated sludge; biochemistry; denitrification; denitrifying microorganisms; nitrates; nitrites; nitrogen; pH; temperature; total nitrogen; wastewater
Abstract:
... A new facultative anaerobic denitrifier was isolated from anoxic activated sludge and identified as Pseudomonas stutzeri strain HK13. Single-factor experiments indicated that the optimal conditions for nitrate removal were a C/N ratio of 8, an initial pH of 7–10, a shaking speed of 100 rpm, and a temperature of 30–40 °C. When 100 mg/L NO₃⁻-N and NO₂⁻-N were used separately as sole nitrogen sources ...
DOI:
10.1016/j.procbio.2022.04.021

19. Chitosan isolated from black soldier flies Hermetia illucens: Structure and enzymatic hydrolysis

Author:
Yong Hyun Lee; Seong Cheol Kim; Kee Dal Nam; Tae Hoon Kim; Byung Ok Jung; Yong-Il Park; Andriy Synytsya; Jae Kweon Park
Source:
Process biochemistry 2022 v.118 pp. 171-181
ISSN:
1359-5113
Subject:
Fourier transform infrared spectroscopy; Hermetia illucens; antioxidant activity; chemical structure; chemical treatment; chitin; chitosan; desorption; enzymatic hydrolysis; gel chromatography; molecular weight; nuclear magnetic resonance spectroscopy
Abstract:
... This study aims to elucidate the biochemical properties of chitosan isolated and purified from larvae of black soldier flies Hermetia illucens to discover and utilize new eco-friendly chitin material. The productivity of chitin obtained from the larvae of black soldier flies H. illucens was found to be approximately 5.00 ± 0.002%. These chitins were converted to chitosan by chemical treatment with ...
DOI:
10.1016/j.procbio.2022.04.020

20. Efficient extraction, physiochemical, rheological properties, and antioxidant activities of polysaccharides from Armeniaca vulgaris Lam

Author:
Wenjuan Sun; Faiza Labreche; Xiao-hong Kou; Cai-E Wu; Gong-Jian Fan; Ting-Ting Li; Andi Suo; Zhihao Wu
Source:
Process biochemistry 2022 v.118 pp. 360-369
ISSN:
1359-5113
Subject:
Prunus armeniaca var. armeniaca; fermentation; hydroxyl radicals; molecular weight; pectins; storage modulus; temperature
Abstract:
... To improve the extraction efficiency of polysaccharides from Armeniaca vulgaris Lam (APP) by microbial fermentation assisted extraction (MFE), the optimal extraction conditions were optimized as follows: fermentation time, 8 h; rotation speed, 145 r/min; inoculation amount, 8%, and fermentation temperature, 31 °C. When compared to hot water extraction (HWE), the yield of APP increased by 79.77%. M ...
DOI:
10.1016/j.procbio.2022.04.032