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- Orden, Alejandro A., et al. Show all 5 Authors
- Process biochemistry 2019 v.79 pp. 114-117
- Rhodotorula rubra; alkynes; ambient temperature; beta adrenergic receptors; bioactive properties; biocatalysts; copper; copper sulfate; cycloaddition reactions; enantiomers; ketones; sodium azide; stereoselectivity; triazoles
- ... Chemoenzymatic strategies for the preparation of enantiopure β-hydroxytriazoles were designed. These and other related compounds are particularly relevant because of their antitubercular bioactivities and as β-adrenergic receptor blockers. The ability of Rhodotorula mucilaginosa LSL to stereoselectively reduce prochiral ketones coupled to copper(I)-catalyzed azide-alkyne cycloaddition was exploite ...