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You searched for: Journal name Proteomics Remove constraint Journal name: Proteomics Publication year rev 7984-2016 Remove constraint Publication year rev: 7984-2016 Source 2016 v.16 no.18 Remove constraint Source: 2016 v.16 no.18
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1. Doubling down on phosphorylation as a variable peptide modification

Author:
Bret Cooper
Source:
Proteomics 2016 v.16 no.18 pp. 2444-2447
ISSN:
1615-9853
Subject:
algorithms; databases; information retrieval; peptides; phosphorylation; proteomics; serine; threonine
Abstract:
... Some mass spectrometrists believe that searching for variable PTMs like phosphorylation of serine or threonine when using database-search algorithms to interpret peptide tandem mass spectra will increase false-positivematching. The basis for this is the premise that the algorithm compares a spectrum to both a nonphosphorylated peptide candidate and a phosphorylated candidate, which is double the n ...
Handle:
10113/5852180
DOI:
10.1002/pmic.201500440