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- Bhattacharya, Maitree, et al. Show all 3 Authors
- RSC advances 2016 v.6 no.111 pp. 109846-109856
- B-DNA; alkaloids; anisotropy; computer simulation; gene therapy; models; spectral analysis; spectroscopy; telomeres; toxicity
- ... The present research compared the binding mechanisms of natural alkaloid harmine (HR) with two structurally different biologically important DNA species, human telomeric 22 G-quadruplex DNA (GQ-DNA) and B-DNA using various steady state and time-resolved spectroscopic techniques. Our study shows that for both DNA species HR has appreciable ground state interaction with comparable binding strengths. ...