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- Ma, Jiale, et al. Show all 9 Authors
- Research in veterinary science 2017 v.115 pp. 109-116
- Escherichia coli; adhesion; animal models; blood; brain; ducklings; endothelial cells; genes; genetic complementation; humans; lethal dose 50; lungs; meningitis; mice; mutants; outer membrane proteins; pathogenesis; phenotype; quantitative polymerase chain reaction; reverse transcriptase polymerase chain reaction; transcription (genetics); virulence
- ... An outer membrane protein T (OmpT) could play a vital role in the pathogenesis of the neonatal meningitis Escherichia coli (NMEC) in human and animals. However, whether ompT plays a role in avian pathogenic E. coli (APEC) infection remains unclear. In this study we evaluated the potential of ompT in APEC pathogenesis. An ompT gene was deleted from APEC mutant strain (TW-XM) was constructed and cha ...