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You searched for: Author "Fernandes, João B." Remove constraint Author: "Fernandes, João B." Journal Revista Brasileira de Farmacognosia Remove constraint Journal: Revista Brasileira de Farmacognosia Subject cathepsin V Remove constraint Subject: cathepsin V Subject fractionation Remove constraint Subject: fractionation
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1. New cathepsin V inhibitor from stems of Bowdichia virgilioides

Author:
Fernandes, João B.,   et al.   ; Silva, Taynara L.; Silva, M. Fátima das G.F. da; Consolaro, Helder N.; Sousa, Lorena R.F. de; Vieira, Paulo C.;     Show all 6 Authors
Source:
Revista Brasileira de Farmacognosia 2019 v.29 no.4 pp. 491-494
ISSN:
0102-695X
Subject:
Bowdichia; beta-sitosterol; cathepsin V; ethyl acetate; fractionation; hexane; lupeol; nuclear magnetic resonance spectroscopy; p-coumaric acid; stems; stigmasterol
Abstract:
... Bioassay-guided fractionation of Bowdichia virgilioides Kunth, Fabaceae, extracts has led to the isolation of cathepsin V inhibitors. The investigation of the hexane and ethyl acetate extracts allowed the characterization of eleven compounds: lupeol, lupenone, β-sitosterol and stigmasterol in mixture, trans p-coumaric acid ester derivative, syringaresinol, bowdenol, 8-methoxycoumestrol, 3,4-hydrox ...
DOI:
10.1016/j.bjp.2019.04.004