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- Thompson, M.; Haeusler, R.A.; Good, P.D.; Engelke, D.R.
- Science 2003 v.302 no.5649 pp. 1399-1401
- DNA-directed RNA polymerase, etc ; Saccharomyces cerevisiae; yeasts; transfer RNA; multigene family; cell nucleolus; fluorescence in situ hybridization; transcription (genetics); Show all 8 Subjects
- ... Early transfer RNA (tRNA) processing events in Saccharomyces cerevisiae are coordinated in the nucleolus, the site normally associated with ribosome biosynthesis. To test whether spatial organization of the tRNA pathway begins with nucleolar clustering of the genes, we have probed the subnuclear location of five different tRNA gene families. The results show that tRNA genes, though dispersed in th ...
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