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- Stanley, Robin E., et al. Show all 3 Authors
- Science 2009 v.325 no.5943 pp. 966-970
- Thermus thermophilus; binding sites; crystal structure; messenger RNA; protein subunits; protein synthesis; ribosomal proteins; ribosomes; transfer RNA
- ... Elongation factor P (EF-P) is an essential protein that stimulates the formation of the first peptide bond in protein synthesis. Here we report the crystal structure of EF-P bound to the Thermus thermophilus 70S ribosome along with the initiator transfer RNA N-formyl-methionyl-tRNAi (fMet-tRNAifMet) and a short piece of messenger RNA (mRNA) at a resolution of 3.5 angstroms. EF-P binds to a site lo ...
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