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- Werner, Christian M., et al. Show all 8 Authors
- The Journal of nutritional biochemistry 2017 v.48 pp. 51-61
- NAD(P)H oxidase (H2O2-forming); NADP (coenzyme); animal models; aorta; apoptosis; atherogenesis; bioactive compounds; biogenesis; endothelial cells; ferulic acid; gene expression; high fat diet; humans; kidneys; lipid peroxidation; liver; messenger RNA; metabolites; mice; mitochondria; mononuclear leukocytes; necrosis; oxidative stress; rice bran; stem cells; sulfonates
- ... The aim of the study was to characterize the vascular effects of rice bran enzymatic extract (RBEE). ApoE−/− mice were fed a high-fat/cholesterol diet (HFD) or HFD supplemented with 5% RBEE for 21 weeks. RBEE prevented development of atherosclerotic plaques and oxidative stress in mouse aorta as well as the down-regulation of markers of mitochondrial biogenesis. Analysis of the bioactive component ...