PubAg

Main content area

You searched for: Subject "peroxisome proliferator-activated receptors" Remove constraint Subject: "peroxisome proliferator-activated receptors" Journal The Journal of nutritional biochemistry Remove constraint Journal: The Journal of nutritional biochemistry
Start Over

Search

57  Search Results

« Previous | 1 - 20 of 57 |
Number of results to display per page

Search Results

1. Phytanic acid activates PPARα to promote beige adipogenic differentiation of preadipocytes

Author:
Wang, Hanning; Mao, Xueying; Du, Min
Source:
The Journal of nutritional biochemistry 2019 v.67 pp. 201-211
ISSN:
0955-2863
Subject:
peroxisome proliferator-activated receptor alpha,   etc   ; adipogenesis; antagonists; biogenesis; brown adipocytes; foods; metabolic diseases; milk fat; mitochondria; obesity; oxygen consumption; stem cells;     Show all 12 Subjects
Abstract:
... A better understanding of the mechanisms of beige and brown adipogenesis is needed for developing strategies to prevent and treat obesity and associated metabolic disorders. Phytanic acid (PA) exists in a wide range of foods, especially in milk fat and marine foods, but its effects on obesity and beige adipogenesis remain poorly defined. The objective is to investigate the effects and regulatory m ...
DOI:
10.1016/j.jnutbio.2019.02.013

2. Gamma-glutamyl carboxylated Gas6 mediates the beneficial effect of vitamin K on lowering hyperlipidemia via regulating the AMPK/SREBP1/PPARα signaling cascade of lipid metabolism

Author:
Bordoloi, Jijnasa; Ozah, Dibyajyoti; Bora, Thaneswar; Kalita, Jatin; Manna, Prasenjit
Source:
The Journal of nutritional biochemistry 2019 v.70 pp. 174-184
ISSN:
0955-2863
Subject:
peroxisome proliferator-activated receptor alpha,   etc   ; AMP-activated protein kinase; animal models; blood lipids; body weight; carboxylation; cholesterol; hepatocytes; high fat diet; homeostasis; hyperlipidemia; lipid metabolism; mice; palmitic acid; protein synthesis; signal transduction; triacylglycerols; vitamin K;     Show all 18 Subjects
Abstract:
... The present study for the first time aims to examine the hypothesis that circulating gamma-glutamyl carboxylated growth arrest specific protein 6 (Gla-Gas6) deficiency may be associated with hyperlipidemia and vitamin K (VK) supplementation may ameliorate the impaired lipid homeostasis via activating Gas6 protein. Subjects with hyperlipidemia (n=22) and age-matched healthy controls (n=19) were inc ...
DOI:
10.1016/j.jnutbio.2019.05.006

3. Resveratrol prevents combined prenatal NG-nitro-L-arginine-methyl ester (L-NAME) treatment plus postnatal high-fat diet induced programmed hypertension in adult rat offspring: interplay between nutrient-sensing signals, oxidative stress and gut microbiota

Author:
Chen, Hung-En; Lin, Yu-Ju; Lin, I-Chun; Yu, Hong-Ren; Sheen, Jiunn-Ming; Tsai, Ching-Chou; Huang, Li-Tung; Tain, You-Lin
Source:
The Journal of nutritional biochemistry 2019 v.70 pp. 28-37
ISSN:
0955-2863
Subject:
peroxisome proliferator-activated receptor gamma,   etc   ; AMP-activated protein kinase; Bacteroidetes; Firmicutes; Verrucomicrobia; adults; blood pressure; drinking water; dysbiosis; high fat diet; hypertension; intestinal microorganisms; lactation; males; nitric oxide; oxidative stress; pregnancy; progeny; rats; resveratrol; therapeutics; weaning;     Show all 22 Subjects
Abstract:
... Oxidative stress, nutrient-sensing signals, high-fat (HF) intake and dysbiosis of gut microbiota are involved in the development of hypertension, a disorder that can originate in early life. We examined whether postnatal HF diet can aggravate maternal NG-nitro-L-arginine-methyl ester (L-NAME) treatment-induced programmed hypertension and whether resveratrol therapy can prevent it. Pregnant Sprague ...
DOI:
10.1016/j.jnutbio.2019.04.002

4. Quercetin and its derivative Q2 modulate chromatin dynamics in adipogenesis and Q2 prevents obesity and metabolic disorders in rats

Author:
Nettore, Immacolata Cristina; Rocca, Carmine; Mancino, Giuseppina; Albano, Luigi; Amelio, Daniela; Grande, Fedora; Puoci, Francesco; Pasqua, Teresa; Desiderio, Silvio; Mazza, Rosa; Terracciano, Daniela; Colao, Annamaria; Bèguinot, Francesco; Russo, Gian Luigi; Dentice, Monica; Macchia, Paolo Emidio; Sinicropi, Maria Stefania; Angelone, Tommaso; Ungaro, Paola
Source:
The Journal of nutritional biochemistry 2019 v.69 pp. 151-162
ISSN:
0955-2863
Subject:
peroxisome proliferator-activated receptor gamma,   etc   ; adipocytes; adipogenesis; beta oxidation; chromatin; epigenetics; gene expression; genes; glucose tolerance; high fat diet; histone demethylases; histones; hyperlipidemia; lipids; moieties; obesity; polyphenols; precipitin tests; quercetin; rats; transcription (genetics); white adipose tissue;     Show all 22 Subjects
Abstract:
... Recently the attention of the scientific community has focused on the ability of polyphenols to counteract adverse epigenetic regulation involved in the development of complex conditions such as obesity. The aim of this study was to investigate the epigenetic mechanisms underlying the anti-adiposity effect of Quercetin (3,3′,4′,5,7-pentahydroxyflavone) and of one of its derivatives, Q2 in which th ...
DOI:
10.1016/j.jnutbio.2019.03.019

5. Dietary patterns influence epicardial adipose tissue fatty acid composition and inflammatory gene expression in the Ossabaw pig

Author:
Walker, Maura E.; Matthan, Nirupa R.; Goldbaum, Audrey; Meng, Huicui; Lamon-Fava, Stefania; Lakshman, Sukla; Jang, Saebyeol; Molokin, Aleksey; Solano-Aguilar, Gloria; Urban, Joseph F.; Lichtenstein, Alice H.
Source:
The Journal of nutritional biochemistry 2019 v.70 pp. 138-146
ISSN:
0955-2863
Subject:
peroxisome proliferator-activated receptor gamma,   etc   ; Toll-like receptor 2; adipose tissue; atorvastatin; biosynthesis; coronary artery disease; dietary fat; dodecanoic acid; eating habits; fatty acid composition; gene expression; genes; heart; inflammation; interleukin-6; nutritional adequacy; omega-3 fatty acids; polyunsaturated fatty acids; saturated fats; swine; therapeutics; unsaturated fats;     Show all 22 Subjects
Abstract:
... Epicardial adipose tissue (EAT) inflammation is implicated in the development and progression of coronary atherosclerosis. Dietary saturated and polyunsaturated fatty acids (SFAs and PUFA) can influence adipose tissue inflammation. We investigated the influence of dietary patterns, with emphasis on dietary fat type, and statin therapy, on EAT fatty acid (FA) composition and inflammatory gene expre ...
DOI:
10.1016/j.jnutbio.2019.04.013

6. Diallyl disulfide potentiates anti-obesity effect of green tea in high-fat/high-sucrose diet-induced obesity

Author:
Bae, Jaehoon; Kumazoe, Motofumi; Fujimura, Yoshinori; Tachibana, Hirofumi
Source:
The Journal of nutritional biochemistry 2019 v.64 pp. 152-161
ISSN:
0955-2863
Subject:
peroxisome proliferator-activated receptors,   etc   ; adipose tissue; cyclic GMP; developed countries; diallyl disulfide; diet; epidemiological studies; fatty acids; fatty-acid synthase; garlic; gene expression regulation; genes; green tea; health services; liver; mice; obesity; obesity-related diseases; protective effect; stearoyl-CoA desaturase; sterols; triacylglycerols;     Show all 22 Subjects
Abstract:
... Obesity is a major problem in developed countries and a burden on social health care systems. Several epidemiological studies showed the protective effects of green tea against obesity-related diseases. Cyclic guanosine monophosphate (cGMP) acts as a mediator for the physiological effects of (−)-epigallocatechin-3-O-gallate, the major constituent of green tea. Here, we showed that the level of pho ...
DOI:
10.1016/j.jnutbio.2018.10.014

7. Apo-10’-lycopenoic acid inhibits cancer cell migration and angiogenesis and induces peroxisome proliferator-activated receptor γ

Author:
Cheng, Junrui; Miao, Benchun; Hu, Kang-Quan; Fu, Xueyan; Wang, Xiang-Dong
Source:
The Journal of nutritional biochemistry 2018 v.56 pp. 26-34
ISSN:
0955-2863
Subject:
peroxisome proliferator-activated receptors,   etc   ; actin; angiogenesis; animal models; cell movement; dose response; gelatinase A; gene expression; humans; liver; lung neoplasms; lungs; lycopene; messenger RNA; metastasis; neoplasm cells; pseudopodia;     Show all 17 Subjects
Abstract:
... We have previously shown that apo-10’-lycopenoic acid (ALA), a derivative of lycopene through cleavage by carotene-9’,10’-oxygenase, inhibits tumor progression and metastasis in both liver and lung cancer animal models. The underlying mechanism remains unknown. We hypothesized that ALA inhibits cancer cell motility and angiogenesis by up-regulating peroxisome proliferator-activated receptor γ (PPA ...
DOI:
10.1016/j.jnutbio.2018.01.003

8. Raspberry ketone induces brown-like adipocyte formation through suppression of autophagy in adipocytes and adipose tissue

Author:
Leu, Sy-Ying; Tsai, Yung-Chieh; Chen, Wen-Chi; Hsu, Chih-Hsiung; Lee, Yen-Mei; Cheng, Pao-Yun
Source:
The Journal of nutritional biochemistry 2018 v.56 pp. 116-125
ISSN:
0955-2863
Subject:
peroxisome proliferator-activated receptors,   etc   ; autophagy; biogenesis; body weight changes; food intake; heme oxygenase (biliverdin-producing); mitochondria; obesity; ovariectomy; raspberries; rats; triacylglycerol lipase; white adipocytes; white adipose tissue;     Show all 14 Subjects
Abstract:
... Promoting white adipose tissue (WAT) to acquire brown-like characteristics is a promising approach for obesity treatment. Although raspberry ketone (RK) has been reported to possess antiobesity activity, its effects on the formation of brown-like adipocytes remain unclear. Therefore, we investigated the effects and underlying mechanism of RK on WAT browning in 3T3-L1 adipocytes and rats with ovari ...
DOI:
10.1016/j.jnutbio.2018.01.017

9. Atrazine-induced environmental nephrosis was mitigated by lycopene via modulating nuclear xenobiotic receptors-mediated response

Author:
Xia, Jun; Lin, Jia; Li, Xue-Nan; Zhang, Cong; Li, Nan; Du, Zheng-Hai; Li, Jin-Long
Source:
The Journal of nutritional biochemistry 2017
ISSN:
0955-2863
Subject:
peroxisome proliferator-activated receptors,   etc   ; atrazine; cytochrome P-450; enzymes; histopathology; homeostasis; kidneys; lycopene; males; mice; morbidity; nephrosis; nephrotoxicity; xenobiotics;     Show all 14 Subjects
Abstract:
... The burden and morbidity of environmental nephrosis is increasing globally. Atrazine (ATR) and degradation products in the environment are considered key determinants of nephrosis. However, the lack of highly effective treatments for environmental nephrosis creates an urgent need to better understand the preventive strategies and mechanisms. This study aimed to highlight the mechanism of ATR-induc ...
DOI:
10.1016/j.jnutbio.2017.09.006

10. Arginine promotes skeletal muscle fiber type transformation from fast-twitch to slow-twitch via Sirt1/AMPK pathway

Author:
Chen, Xiaoling; Guo, Yafei; Jia, Gang; Liu, Guangmang; Zhao, Hua; Huang, Zhiqing
Source:
The Journal of nutritional biochemistry 2018 v.61 pp. 155-162
ISSN:
0955-2863
Subject:
peroxisome proliferator-activated receptor gamma,   etc   ; AMP-activated protein kinase; arginine; gene expression; lactate dehydrogenase; malate dehydrogenase; messenger RNA; mice; myosin heavy chains; myotubes; nitric oxide; nitric oxide synthase; protein content; protein synthesis;     Show all 14 Subjects
Abstract:
... This study investigated the effect of arginine on skeletal muscle fiber type transformation in mice and in C2C12 myotubes. Our data showed that dietary supplementation of arginine in mice significantly up-regulated the slow myosin heavy chain (MyHC), troponin I-SS, sirtuin1 (Sirt1) and peroxisome proliferator activated receptor-γ coactivator-1α (PGC-1α) protein expressions, as well as significantl ...
DOI:
10.1016/j.jnutbio.2018.08.007

11. Identification of activation of tryptophan–NAD+ pathway as a prominent metabolic response to thermally oxidized oil through metabolomics-guided biochemical analysis

Author:
Wang, Lei; Yao, Dan; Urriola, Pedro E.; Hanson, Andrea R.; Saqui-Salces, Milena; Kerr, Brian J.; Shurson, Gerald C.; Chen, Chi
Source:
The Journal of nutritional biochemistry 2018 v.57 pp. 255-267
ISSN:
0955-2863
Subject:
peroxisome proliferator-activated receptors,   etc   ; ascorbic acid; beta oxidation; biochemical pathways; blood serum; diet; gene expression regulation; glutathione; liver; metabolic diseases; metabolites; metabolome; mice; nicotinamide; oxidation; phospholipids; soybean oil; triacylglycerols; tryptophan; urine;     Show all 20 Subjects
Abstract:
... Consumption of thermally oxidized oil is associated with metabolic disorders, but oxidized oil-elicited changes in the metabolome are not well defined. In this study, C57BL/6 mice were fed the diets containing either control soybean oil or heated soybean oil (HSO) for 4 weeks. HSO-responsive metabolic events were examined through untargeted metabolomics-guided biochemical analysis. HSO directly co ...
Handle:
10113/5974741
DOI:
10.1016/j.jnutbio.2018.04.009

12. Improvement of cardiometabolic markers after fish oil intervention in young Mexican adults and the role of PPARα L162V and PPARγ2 P12A

Author:
Binia, Aristea; Vargas-Martínez, Carolina; Ancira-Moreno, Mónica; Gosoniu, Laura M.; Montoliu, Ivan; Gámez-Valdez, Elí; Soria-Contreras, Diana C.; Angeles-Quezada, Adriana; Gonzalez-Alberto, Rocío; Fernández, Silvia; Martínez-Conde, Diego; Hernández-Morán, Brianda; Ramírez-Solano, Marisol; Pérez-Ortega, Carlos; Rodríguez-Carmona, Yanelli; Castan, Isabelle; Rubio-Aliaga, Isabel; Vadillo-Ortega, Felipe; Márquez-Velasco, Ricardo; Bojalil, Rafael; López-Alvarenga, Juan Carlos; Valet, Philippe; Kussmann, Martin; Silva-Zolezzi, Irma; Tejero, M Elizabeth
Source:
The Journal of nutritional biochemistry 2017 v.43 pp. 98-106
ISSN:
0955-2863
Subject:
peroxisome proliferator-activated receptors,   etc   ; adiponectin; alleles; body composition; fish oils; genotype; glucose; glycohemoglobin; inflammation; insulin; ligands; metabolism; people; polyunsaturated fatty acids; triacylglycerols; young adults;     Show all 16 Subjects
Abstract:
... Polyunsaturated fatty acids (PUFA) contained in fish oil (FO) are ligands for peroxisome proliferator-activated receptors (PPAR) that may induce changes in cardiometabolic markers. Variation in PPAR genes may influence the beneficial responses linked to FO supplementation in young adults. The study aimed to analyze the effect of FO supplementation on glucose metabolism, circulating lipids and infl ...
DOI:
10.1016/j.jnutbio.2017.02.002

13. Quercetin metabolites inhibit MMP-2 expression in A549 lung cancer cells by PPAR-γ associated mechanisms

Author:
Chuang, Cheng-Hung; Yeh, Chiao-Lin; Yeh, Shu-Lan; Lin, En-Shyh; Wang, Li-Yu; Wang, Ying-Hsuna
Source:
The Journal of nutritional biochemistry 2016 v.33 pp. 45-53
ISSN:
0955-2863
Subject:
peroxisome proliferator-activated receptors,   etc   ; protein synthesis; dose response; lung neoplasms; antagonists; metalloproteinases; ligands; neoplasm cells; quercetin; metabolites;     Show all 10 Subjects
Abstract:
... Our previous study demonstrated that quercetin-metabolite-enriched plasma (QP) but not quercetin itself upregulates peroxisome proliferator-activated receptor gamma (PPAR-γ) expression to induce G2/M arrest in A549 cells. In the present study, we incubated A549 cells with QP as well as quercetin-3-glucuronide (Q3G) and quercetin-3′-sulfate (Q3′S), two major metabolites of quercetin, to investigate ...
DOI:
10.1016/j.jnutbio.2016.03.011

14. Bio-accessible milk casein derived tripeptide (LLY) mediates overlapping anti- inflammatory and anti-oxidative effects under cellular (Caco-2) and in vivo milieu

Author:
Sowmya, Kandukuri; Mala, Dev; Bhat, Mohd Iqbal; Kumar, Naveen; Bajaj, Rajesh Kumar; Kapila, Suman; Kapila, Rajeev
Source:
The Journal of nutritional biochemistry 2018 v.62 pp. 167-180
ISSN:
0955-2863
Subject:
peroxisome proliferator-activated receptor alpha,   etc   ; anti-inflammatory activity; antioxidant activity; casein; catalase; disease prevention; ethanol; gene expression; genes; human cell lines; hydrogen peroxide; inflammation; interferon-gamma; interleukin-10; liver; macrophages; mice; milk; models; oxidative stress; phagocytosis; splenocytes; superoxide dismutase; transforming growth factor beta; tumor necrosis factor-alpha;     Show all 25 Subjects
Abstract:
... Inflammation and oxidative stress are closely linked patho-physiological processes which occur concurrently in many diseased conditions. Recently, interdependence between these two processes explains the antioxidant paradox associated with failure to select appropriate agents required for prevention of diseases known to be induced by oxidative stress. Present study established the overlapping anti ...
DOI:
10.1016/j.jnutbio.2018.09.002

15. Long-term exposure to high-sucrose diet down-regulates hepatic endoplasmic reticulum-stress adaptive pathways and potentiates de novo lipogenesis in weaned male mice

Author:
Flister, Karla Frida Torres; Pinto, Bruno Araújo Serra; França, Lucas Martins; Coêlho, Caio Fernando Ferreira; dos Santos, Pâmela Costa; Vale, Caroline Castro; Kajihara, Daniela; Debbas, Victor; Laurindo, Francisco Rafael Martins; Paes, Antonio Marcus de Andrade
Source:
The Journal of nutritional biochemistry 2018 v.62 pp. 155-166
ISSN:
0955-2863
Subject:
peroxisome proliferator-activated receptor alpha,   etc   ; added sugars; adiposity; antioxidant activity; apoptosis; beta oxidation; childhood; chronic exposure; endoplasmic reticulum; fatty acids; fatty liver; gene expression regulation; gene overexpression; genes; glucose; high carbohydrate diet; hyperglycemia; hyperinsulinemia; hypertriglyceridemia; insulin resistance; laboratory animals; lipogenesis; males; metabolic syndrome; mice; oxidation; protein content; rats; sucrose; transcription (genetics); unfolded protein response;     Show all 31 Subjects
Abstract:
... Childhood consumption of added sugars, such as sucrose, has been associated to increased risk of metabolic syndrome (MetS) and nonalcoholic fatty liver disease (NAFLD). Although the mechanisms underlying NAFLD onset are incompletely defined, recent evidence has proposed a role for the endoplasmic reticulum (ER) stress. Thus, the present study sought to investigate the metabolic outcomes of high-su ...
DOI:
10.1016/j.jnutbio.2018.09.007

16. Fecal fermentation products of common bean-derived fiber inhibit C/EBPα and PPARγ expression and lipid accumulation but stimulate PPARδ and UCP2 expression in the adipogenesis of 3T3-L1 cells

Author:
Lu, Hsin-Yi; Zeng, Huawei; Zhang, Li; Porres, Jesus M.; Cheng, Wen-Hsing
Source:
The Journal of nutritional biochemistry 2018 v.60 pp. 9-15
ISSN:
0955-2863
Subject:
peroxisome proliferator-activated receptor gamma,   etc   ; Phaseolus vulgaris; adipocytes; adipogenesis; antibiotics; bean flour; beans; dietary fiber; energy expenditure; fatty acid-binding proteins; feces; fermentation; fermented foods; freeze drying; in vitro digestion; intestinal microorganisms; lipids; mechanism of action; messenger RNA; mice; mitochondria; models; obesity; protein content; transactivators; weight loss;     Show all 26 Subjects
Abstract:
... Clinical and animal studies have suggested efficacies of common bean (Phaseolus vulgaris) consumption on weight loss. Fermentation of common bean-derived dietary fiber by gut microbiota is proposed to mitigate obesity; however, the mechanism of action is unclear. The objective of this study was to investigate whether and how fecal fermentation of common bean-derived dietary fiber impacts adipogene ...
DOI:
10.1016/j.jnutbio.2018.06.004

17. The olive constituent oleuropein, as a PPARα agonist, markedly reduces serum triglycerides

Author:
Malliou, Foteini; Andreadou, Ioanna; Gonzalez, Frank J.; Lazou, Antigone; Xepapadaki, Eva; Vallianou, Ioanna; Lambrinidis, George; Mikros, Emmanuel; Marselos, Marios; Skaltsounis, Alexios-Leandros; Konstandi, Maria
Source:
The Journal of nutritional biochemistry 2018 v.59 pp. 17-28
ISSN:
0955-2863
Subject:
peroxisome proliferator-activated receptor alpha,   etc   ; adults; agonists; antioxidants; blood serum; carboxylic ester hydrolases; cholesterol; computer simulation; energy; gene expression; gene expression regulation; homeostasis; infarction; ligands; lipemic effect; liver; luciferase; males; metabolism; mice; oleuropein; olives; rabbits; reporter genes; triacylglycerols; white adipose tissue;     Show all 26 Subjects
Abstract:
... Oleuropein (OLE), a main constituent of olive, exhibits antioxidant and hypolipidemic effects, while it reduces the infarct size in chow- and cholesterol-fed rabbits. Peroxisome proliferator-activated receptor α (PPARα) has essential roles in the control of lipid metabolism and energy homeostasis. This study focused on the mechanisms underlying the hypolipidemic activity of OLE and, specifically, ...
DOI:
10.1016/j.jnutbio.2018.05.013

18. A- type ECG and EGCG dimers disturb the structure of 3T3-L1 cell membrane and strongly inhibit its differentiation by targeting peroxisome proliferator-activated receptor γ with miR-27 involved mechanism

Author:
Zhu, Wei; Zou, Bo; Nie, Rongzu; Zhang, Ying; Li, Chun-mei
Source:
The Journal of nutritional biochemistry 2015 v.26 pp. 1124-1135
ISSN:
0955-2863
Subject:
peroxisome proliferator-activated receptors,   etc   ; adipocytes; adipogenesis; cell membranes; hydrophobicity; hyperplasia; lipids; membrane permeability; proanthocyanidins;     Show all 9 Subjects
Abstract:
... The effects of four proanthocyanidin dimers including epicatechin-(4β→8, 2β→O→7)-epicatechin (A-type EC dimer), epicatechin-(4β→8)-epicatechin (B-type EC dimer), epicatechin-3-gallate-(4β→8, 2β→O→7)-epicatechin-3-gallate (A-type ECG dimer) and epigallocatechin-3-gallate-(4β→8, 2β→O→7)-epigallocatechin-3-gallate (A-type EGCG dimer) on 3T3-L1 preadipocyte cell differentiation and the underlying mech ...
DOI:
10.1016/j.jnutbio.2015.05.006

19. Effects of the dietary carbohydrate–fat ratio on plasma phosphatidylcholine profiles in human and mouse

Author:
Inoue, Mizuki; Senoo, Nanami; Sato, Tomoki; Nishimura, Yuri; Nakagawa, Takumi; Miyoshi, Noriyuki; Goda, Toshinao; Morita, Akihito; Miura, Shinji
Source:
The Journal of nutritional biochemistry 2017 v.50 pp. 83-94
ISSN:
0955-2863
Subject:
peroxisome proliferator-activated receptors,   etc   ; Japanese people; biomarkers; cross-sectional studies; diet history; dieting; fatty acid metabolism; fatty acids; glucose; high carbohydrate diet; high fat diet; humans; ligands; lipogenesis; lipoproteins; liquid chromatography; liver; mass spectrometry; men; mice; phosphatidylcholines; questionnaires;     Show all 22 Subjects
Abstract:
... Phosphatidylcholines (PCs), a major class of human plasma phospholipids, are composed of highly diverse fatty acids. Because the dietary carbohydrate–fat ratio alters the hepatic fatty acid metabolism, plasma fatty acids that bind PCs, which are secreted as lipoproteins from the liver, may be affected by long-term consumption of a high-carbohydrate diet or a high-fat diet. Therefore, in this study ...
DOI:
10.1016/j.jnutbio.2017.08.018

20. Resveratrol prevents the combined maternal plus postweaning high-fat-diets-induced hypertension in male offspring

Author:
Tain, You-Lin; Lin, Yu-Ju; Sheen, Jiunn-Ming; Lin, I-Chun; Yu, Hong-Ren; Huang, Li-Tung; Hsu, Chien-Ning
Source:
The Journal of nutritional biochemistry 2017 v.48 pp. 120-127
ISSN:
0955-2863
Subject:
peroxisome proliferator-activated receptors,   etc   ; AMP-activated protein kinase; adults; antioxidants; autophagy; drinking water; females; high fat diet; hypertension; kidneys; lactation; males; nitric oxide; oxidative stress; pregnancy; progeny; protective effect; rats; renin-angiotensin system; resveratrol; risk; vasodilation; weaning;     Show all 23 Subjects
Abstract:
... Maternal high-fat (HF) diet is believed to induce oxidative stress and activate nutrient-sensing signals, which increase the risk of adult offspring to develop hypertension. We investigated whether resveratrol prevents the combined maternal plus postweaning HF-diets-induced hypertension in adult male offspring, with a focus on the kidney. Female Sprague–Dawley rats received either a normal diet (N ...
DOI:
10.1016/j.jnutbio.2017.06.007