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- LoPachin, Richard M.; Geohagen, Brian C.; Nordstroem, Lars U.
- Toxicology 2019 v.418 pp. 62-69
- Lewis acids; Lewis bases; chemical bonding; chemical reactions; hardness; molecular biology; organic chemistry; quantum mechanics; synaptic transmission; toxicity; toxicology; xenobiotics
- ... Electron-deficient chemicals (electrophiles) react with compounds that have one or more unshared valence electron pairs (nucleophiles). The resulting covalent reactions between electrophiles and nucleophiles (e.g., Michael addition, SN2 reactions) are important, not only to Organic Chemistry, but also to the fields of Molecular Biology and Toxicology. Specifically, covalent bond formation is the o ...
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