Journal: Toxicon / Publication Year: 2019 / Source: 2019 v.169

Author:: Kote, Sachin; Faktor, Jakub; Dapic, Irena; Mayordomo, Marcos Yebenes; Kocikowski, Mikołaj; Kagansky, Alexander; Goodlett, David; Vojtesek, Borivoj; Hupp, Ted; Wilcockson, David; Piper, Ross
Source:: Toxicon 2019 v.169 pp. 1-4
ISSN:: 0041-0101
Subject:: Cerceris; mass spectrometry; parasitic wasps; proteome; proteomics; transcriptome; venoms; wasps
Abstract:: ... Solitary aculeate wasps are abundant and diverse hymenopteran insects that disable prey using venom. The venom may possess neuromodulation, immunomodulatory, metabolic-modulatory and antimicrobial functions. Venom analysis of transcriptomes and proteomes has been previously performed in social and parasitoid wasp species. We develop methodologies including mass spectrometry-based shotgun proteomic ...
DOI:: 10.1016/j.toxicon.2019.07.012
: https://dx.doi.org/10.1016/j.toxicon.2019.07.012

Author:: Melo, Fabrício Gomes; Ocarino, Natália Melo; Sena Reis, Amanda Maria; Gomes, Lorenna Alves; Magalhães Cardoso, Kênia Mara; Gimeno, Eduardo Juan; Massone, Adriana Raquel; Melo, Marília Martins; Machado Botelho, Ana Flávia; Serakides, Rogéria
Source:: Toxicon 2019 v.169 pp. 25-33
ISSN:: 0041-0101
Subject:: Solanum glaucophyllum; bone formation; bone marrow; cell culture; culture media; genes; liquid chromatography; mesenchymal stromal cells; metaplasia; mineralization; models; pathogenesis; plant extracts; poisoning; rats
Abstract:: ... The hypothesis of this experiment is that mesenchymal stem cells (MSCs) are involved in the genesis of the bone metaplasia caused by Solanum glaucophyllum intoxication. We determined using liquid chromatography that 1 mL of plant extract contained 3.8 μl of 1,25(OH)2D3. The ability of 100 μL, 1 mL and 5 mL of extract/L, containing 1 nM (0.4 μg/L), 10 nM (4 μg/L) and 50 nM (20 μg/L) of 1,25(OH)2D3, ...
DOI:: 10.1016/j.toxicon.2019.08.003
: https://dx.doi.org/10.1016/j.toxicon.2019.08.003

Author:: Witharana, E.W.R.A.; Gnanathasan, A.; Dissanayake, A.S.; Wijesinghe, S.K.J.; Kadahetti, S.C.L.; Rajapaksha, R.M.J.K.
Source:: Toxicon 2019 v.169 pp. 34-37
ISSN:: 0041-0101
Subject:: Trimeresurus trigonocephalus; blisters; blood; feet; hands; hospitals; lymphatic diseases; morbidity; nephrotoxicity; neurotoxicity; observational studies; pain; patients; photographs; plantations; risk factors; shoulders; snake bites; snakes; tea; thighs; tropical rain forests; villages; Sri Lanka
Abstract:: ... Green pit viper (Trimeresurus trigonocephalus) is endemic to Sri Lanka and bites are reported from tropical rain forest and plantation areas. As scant data exists on clinico-epidemiological features of Sri Lankan green pit viper bite, objective of this study was to address this knowledge gap. A prospective observational study was conducted in Base Hospital Deniyaya from October 2013 to September 2 ...
DOI:: 10.1016/j.toxicon.2019.07.011
: https://dx.doi.org/10.1016/j.toxicon.2019.07.011

Author:: Rincón-Cortés, Clara Andrea; Olamendi-Portugal, Timoteo; Carcamo-Noriega, Edson Norberto; Santillán, Edmundo González; Zuñiga, Fernando Zamudio; Reyes-Montaño, Edgar Antonio; Vega Castro, Nohora Angélica; Possani, Lourival Domingos
Source:: Toxicon 2019 v.169 pp. 5-11
ISSN:: 0041-0101
Subject:: Centruroides; Orthoptera; Tityus; amino acids; chromatography; disulfide bonds; disulfides; humans; insects; molecular weight; peptides; phylogeny; sodium channels; topology; toxicity; toxins; venoms
Abstract:: ... The soluble venom of the scorpion Tityus macrochirus was separated by chromatographic procedures and three homogeneous peptides were obtained and their primary structures were determined. They were called: Tma1-Tma3, from the abbreviated name of the scorpion. Tma1 is a peptide containing 65 amino acids with four disulfide linkages and a molecular weight of 7386.2 Da. It is a mammalian toxin, shown ...
DOI:: 10.1016/j.toxicon.2019.07.013
: https://dx.doi.org/10.1016/j.toxicon.2019.07.013

Main content area