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You searched for: Journal name Trends in analytical chemistry Remove constraint Journal name: Trends in analytical chemistry Publication year rev 7979-2021 Remove constraint Publication year rev: 7979-2021 Source 2021 v.135 Remove constraint Source: 2021 v.135
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1. A guide to good practice in chemometric methods for vibrational spectroscopy, electrochemistry, and hyphenated mass spectrometry

Author:
Manuel David Peris-Díaz; Artur Krężel
Source:
Trends in analytical chemistry 2021 v.135 pp. 116157
ISSN:
0165-9936
Subject:
chemometrics; data analysis; electrochemistry; experimental design; mass spectrometry; mathematical models; research
Abstract:
... Chemometric methods are powerful tools used in analytical sciences and beyond. Their application is continuously increasing due in part to the technological advances that allow exploration of new issues. This review presents the most common chemometric tools utilized in the most recent research articles (2018 to now), which emerge at the interface between several disciplines and instrumental techn ...
DOI:
10.1016/j.trac.2020.116157

2. Chromatography hyphenated to high resolution mass spectrometry in untargeted metabolomics for investigation of food (bio)markers

Author:
Leticia Lacalle-Bergeron; David Izquierdo-Sandoval; Juan V. Sancho; Francisco J. López; Félix Hernández; Tania Portolés
Source:
Trends in analytical chemistry 2021 v.135 pp. 116161
ISSN:
0165-9936
Subject:
chromatography; food analysis; foods; mass spectrometry; metabolites; metabolomics
Abstract:
... Currently, there is a growing demand by our society, authorities and science to increase the knowledge about the quality of food and its relationship with health and disease. Untargeted metabolomics approaches are emerging as powerful tools for exploring metabolic changes in biological systems under different conditions with great potential in the food field. To this aim, it is necessary to apply ...
DOI:
10.1016/j.trac.2020.116161

3. Chromatography-MS based metabolomics applied to the study of virgin olive oil bioactive compounds: Characterization studies, agro-technological investigations and assessment of healthy properties

Author:
Lucía Olmo-García; Alegría Carrasco-Pancorbo
Source:
Trends in analytical chemistry 2021 v.135 pp. 116153
ISSN:
0165-9936
Subject:
analytical chemistry; bioactive compounds; fields; information; mass spectrometry; metabolomics; phenolic compounds; phytosterols; tocopherols; virgin olive oil
Abstract:
... The potential health benefits of virgin olive oil (VOO) are incontestable and, thus, its consumption and production is spreading all over the world. Among all VOO components, triterpenic and phenolic compounds, tocopherols and phytosterols attract a lot of attention; their determination is analytically challenging but the development of innovative, ambitious, robust, efficient and sensitive analyt ...
DOI:
10.1016/j.trac.2020.116153

4. Electrochemical sensors targeting salivary biomarkers: A comprehensive review

Author:
Veerappan Mani; Tutku Beduk; Walaa Khushaim; Ayse Elcin Ceylan; Suna Timur; Otto S. Wolfbeis; Khaled Nabil Salama
Source:
Trends in analytical chemistry 2021 v.135 pp. 116164
ISSN:
0165-9936
Subject:
Alzheimer disease; accuracy; administrative management; analytical chemistry; assays; biomarkers; cardiovascular diseases; cost effectiveness; diabetes; drug abuse; electrochemistry; forensic sciences; medicine; microfluidic technology; mobile telephones; monitoring; nanomaterials; saliva; sampling; sensors (equipment); toxicology
Abstract:
... The analysis of salivary markers has grown into a promising non-invasive route for easy, safe, and pain-free monitoring and has the potential to alter the existing way of clinical diagnosis and management. Advancements in sensing technology, the arrival of novel materials, the innovative fabrication technologies, and sampling accuracy have made significant progress and establishing saliva as a flu ...
DOI:
10.1016/j.trac.2020.116164

5. Monitoring of electrochemical reactions on different electrode configurations by ambient mass spectrometry

Author:
Weixiang Li; Jianghui Sun; Yixuan Gao; Ying Zhang; Jin Ouyang; Na Na
Source:
Trends in analytical chemistry 2021 v.135 pp. 116180
ISSN:
0165-9936
Subject:
analytical chemistry; batteries; chemical species; design; electrochemistry; electrodes; fields; information; light; mass spectrometry; monitoring; pretreatment; reaction mechanisms; synthesis; voltammetry
Abstract:
... Monitoring of electrochemical (EC) reactions is crucial to obtain efficient, fast and inexpensive reactions for synthesis or analysis. Traditional characterizations by cyclic voltammetry or spectroscopic techniques are usually limited by the lack of detailed structural information on analytes. Without any sample pretreatment, ambient mass spectrometry (AMS) can directly provide structural informat ...
DOI:
10.1016/j.trac.2021.116180

6. Preparation and electrochemical sensing application of porous conducting polymers

Author:
Zhen Song; Yihui Ma; Aoife Morrin; Caifeng Ding; Xiliang Luo
Source:
Trends in analytical chemistry 2021 v.135 pp. 116155
ISSN:
0165-9936
Subject:
active sites; analytical chemistry; electrochemistry; polymers; surface area; synthesis
Abstract:
... Porous conducting polymers (PCPs) are a kind of unique conducting polymers (CPs) material that integrate the excellent electrochemical properties of the material itself and the advantages of the porous structure. Compared with conventional conducting polymers, PCPs have larger specific surface area associated with more active sites, along with higher electrocatalytic activity. PCPs have received i ...
DOI:
10.1016/j.trac.2020.116155

7. Recent developments of point-of-care (POC) testing platform for biomolecules

Author:
Yanawut Manmana; Takuya Kubo; Koji Otsuka
Source:
Trends in analytical chemistry 2021 v.135 pp. 116160
ISSN:
0165-9936
Subject:
Coronavirus infections; analytical chemistry; biochemical compounds; case studies; design; developed countries; humans; pandemic; point-of-care systems; researchers; testing
Abstract:
... Point-of-care (POC) testing devices are necessary to improve human life with many aspects both for developing and developed countries. Especially, the specific biomolecules, which are related to particular diseases, are the important targets for POC testing. Recently, many researchers are able to develop POC devices in various platforms and designs due to the discovery and development of new advan ...
DOI:
10.1016/j.trac.2020.116160

8. Recent electrokinetic strategies for isolation, enrichment and separation of extracellular vesicles

Author:
Marco Morani; Thanh Duc Mai; Zuzana Krupova; Guillaume van Niel; Pierre Defrenaix; Myriam Taverna
Source:
Trends in analytical chemistry 2021 v.135 pp. 116179
ISSN:
0165-9936
Subject:
analytical chemistry; biomarkers; body fluids; drugs; infancy; knowledge; methodology; microfluidic technology; nanocarriers; physicochemical properties; quality control; separation
Abstract:
... Extracellular vesicles (EVs) are a family of cell-derived membrane vesicles that are present in almost all body fluids. EVs have gained significant interest over the last decades as mediators of key functions in numerous patho-physiological condition (clearance, signalling, trophic support, cargo delivery) and as potential prognostic or diagnostic biomarkers. The endogenous delivery capacities of ...
DOI:
10.1016/j.trac.2021.116179

9. Semiconductor photoelectroanalysis and photobioelectroanalysis: A perspective

Author:
Sirlon F. Blaskievicz; Lucia Helena Mascaro; Yuanzhu Zhao; Frank Marken
Source:
Trends in analytical chemistry 2021 v.135 pp. 116154
ISSN:
0165-9936
Subject:
analytical chemistry; detection; electrodes; light intensity; materials; semiconductors; sensors (equipment)
Abstract:
... Electrochemical sensor signal output, when recorded as a current, is primarily related to the target analyte concentration, but often also related to additional experimental or control parameters. When employing photo-active semiconductor electrodes, light intensity offers an additional control parameter for sensors and opportunities for new reaction/detection or signal amplification pathways. Lig ...
DOI:
10.1016/j.trac.2020.116154

10. Soil spectroscopy with the use of chemometrics, machine learning and pre-processing techniques in soil diagnosis: Recent advances–A review

Author:
Issam Barra; Stephan M. Haefele; Ruben Sakrabani; Fassil Kebede
Source:
Trends in analytical chemistry 2021 v.135 pp. 116166
ISSN:
0165-9936
Subject:
artificial intelligence; chemometrics; cost effectiveness; diagnostic techniques; estimation; fertilizers; laboratories; physicochemical properties; prediction; soil; spectroscopy; sustainable technology
Abstract:
... Over the past two decades soil spectroscopy, particularly, in the infrared range, is becoming a powerful technique to simplify analysis relative to the traditional chemical methods. It is known as a rapid, cost-effective, quantitative and eco-friendly technique, which can provide hyperspectral data with narrow and numerous wavebands, both in the laboratory and in the field. In this context, the pr ...
DOI:
10.1016/j.trac.2020.116166

11. Untargeted approaches in food-omics: The potential of comprehensive two-dimensional gas chromatography/mass spectrometry

Author:
Federico Stilo; Carlo Bicchi; Albert Robbat; Stephen E. Reichenbach; Chiara Cordero
Source:
Trends in analytical chemistry 2021 v.135 pp. 116162
ISSN:
0165-9936
Subject:
analytical chemistry; comprehensive two-dimensional gas chromatography; data analysis; foodomics; gas chromatography-mass spectrometry; information; information processing; literature; olfactometry; sensory evaluation
Abstract:
... The contribution focuses on untargeted data processing/analysis approaches that are currently adopted to explore the 4D-data matrices produced by comprehensive two-dimensional gas chromatography-mass spectrometry (GC × GC-MS) in food-omics. Strategies for untargeted explorations are rationalized through the type of features adopted (i.e., visual, datapoint, peak, and peak-regions) at the data proc ...
DOI:
10.1016/j.trac.2020.116162

12. Current role of modern chromatography and mass spectrometry in the analysis of mycotoxins in food

Author:
Deyber Arley Vargas Medina; João Victor Bassolli Borsatto; Edvaldo Vasconcelos Soares Maciel; Fernando Mauro Lanças
Source:
Trends in analytical chemistry 2021 v.135 pp. 116156
ISSN:
0165-9936
Subject:
analytical chemistry; carcinogenicity; crops; food matrix; gastrointestinal diseases; humans; ionization; liquid chromatography; mass; mass spectrometry; monitoring; mycotoxins; natural toxicants; nervous system; pesticides; plague; quantitative analysis; sampling; screening; vegetables; veterinary drugs
Abstract:
... The constant surveillance regarding how much safe the food we are intaking has become a critical point in current science since its quality directly affects our health. Several chemicals are used to control plague, diseases, or as health promoters in crops and animals. Although the main classes being controlled are pesticides and veterinary drugs, considerable attention has been targeted to mycoto ...
DOI:
10.1016/j.trac.2020.116156

13. Recent advances of 3D printing in analytical chemistry: Focus on microfluidic, separation, and extraction devices

Author:
Lujun Wang; Martin Pumera
Source:
Trends in analytical chemistry 2021 v.135 pp. 116151
ISSN:
0165-9936
Subject:
analytical chemistry; biosensors; chemists; extraction; fields; materials; pretreatment; separation; three-dimensional printing
Abstract:
... 3D printing has attracted the attention of analytical chemists. 3D printing possesses the merits of fast and low-cost fabrication of geometrically complex 3D structures and has been employed in the fields of microfluidic devices, electrochemical sensors and biosensors, separation sciences, sample pretreatment, and wearable sensors. We focus on the applications and materials of 3D printing in micro ...
DOI:
10.1016/j.trac.2020.116151

14. Recent advances of bimetallic nanomaterials and its nanocomposites for biosensing applications

Author:
Ruth Stephanie; Min Woo Kim; Sung Hyun Kim; Jang-Kyo Kim; Chan Yeong Park; Tae Jung Park
Source:
Trends in analytical chemistry 2021 v.135 pp. 116159
ISSN:
0165-9936
Subject:
analytical chemistry; behavior; biomimetics; biosensors; chemical species; detection; electrodes; information; nanocomposites; nanomaterials; synthesis
Abstract:
... Biosensors hold prominent role in the detection of various analytes related to bioanalytical applications, i.e., biosensing. One of the strategies used to increase the biosensing capability of a biosensor is by decorating the sensing electrode with advanced material, one of which is bimetallic nanomaterials and its nanocomposites, that greatly enhance the specificity and sensitivity of biosensors. ...
DOI:
10.1016/j.trac.2020.116159

15. Review of sensing technologies for measuring powder density variations during pharmaceutical solid dosage form manufacturing

Author:
S. Stranzinger; D. Markl; J.G. Khinast; A. Paudel
Source:
Trends in analytical chemistry 2021 v.135 pp. 116147
ISSN:
0165-9936
Subject:
X-radiation; acoustics; analytical chemistry; density; drug formulations; drugs; image analysis; information processing; manufacturing; measurement; monitoring; near-infrared spectroscopy; particles; particulates; processing time; tomography; ultrasonic treatment
Abstract:
... Oral solid dosage forms, the most widely used pharmaceutical products, are typically manufactured through a series of processes that transform a blend of drug and excipient particles into a densified product with consistent quality attributes. While the densification of powder during processing is crucial and directly impacts the quality of the drug product, there is still scarcity of non-destruct ...
DOI:
10.1016/j.trac.2020.116147

16. Solid-state NMR spectroscopy in pharmaceutical sciences

Author:
Mingyue Li; Wei Xu; Yongchao Su
Source:
Trends in analytical chemistry 2021 v.135 pp. 116152
ISSN:
0165-9936
Subject:
analytical chemistry; drugs; knowledge; materials; nuclear magnetic resonance spectroscopy; solids
Abstract:
... Solid-state NMR (ssNMR) spectroscopy analyzes a wide range of pharmaceutical materials in a non-disruptive and non-invasive manner. The obtained molecular properties at macroscopic and microscopic scales offer critical knowledge on the physiochemical stability of drug substances and drug products. ssNMR is well suited to characterize multicomponent solids, providing insight into the formulation pr ...
DOI:
10.1016/j.trac.2020.116152

17. Advanced nanomaterials as sample technique for bio-analysis

Author:
Nianrong Sun; Hailong Yu; Hao Wu; Xizhong Shen; Chunhui Deng
Source:
Trends in analytical chemistry 2021 v.135 pp. 116168
ISSN:
0165-9936
Subject:
analytical chemistry; cells; environment; metabolites; nanomaterials; nucleic acids; peptides; proteins; salts; therapeutics
Abstract:
... The biological compositions including cells, proteins/peptides, nucleic acids, extracellular vesicles (EVs) and metabolites are no doubt closely related to almost all physiological and pathological events in organism. Parts of them with specific characteristics can serve as therapeutic target or even disease indicator at early stage. However, all of them especially the specific portion associated ...
DOI:
10.1016/j.trac.2020.116168

18. Assessing reactive oxygen and nitrogen species in atmospheric and aquatic environments: Analytical challenges and opportunities

Author:
Eliana F.C. Simões; Antoine S. Almeida; Armando C. Duarte; Regina M.B.O. Duarte
Source:
Trends in analytical chemistry 2021 v.135 pp. 116149
ISSN:
0165-9936
Subject:
aerosols; air; air pollution; analytical chemistry; aquatic environment; carbon nanoparticles; chemical composition; climate; detection; nitrogen; oxygen; particles; particulates; surface water
Abstract:
... Reactive oxygen and nitrogen species (ROS and RNS) play a crucial role in biotic and abiotic processes. In the atmosphere, ROS/RNS are usually associated with air pollution. The ability of certain air particulate matter constituents to influence the formation and cycling of ROS/RNS at the atmosphere-biosphere-hydrosphere interfaces is important for the observed linkages between atmospheric aerosol ...
DOI:
10.1016/j.trac.2020.116149

19. Chemometric applications in metabolomic studies using chromatography-mass spectrometry

Author:
Alessandra Paul; Peter de Boves Harrington
Source:
Trends in analytical chemistry 2021 v.135 pp. 116165
ISSN:
0165-9936
Subject:
artificial intelligence; chemometrics; data analysis; data collection; experimental design; mass spectrometry; metabolome; metabolomics; models; pipelines; research; researchers; solutions; statistical analysis
Abstract:
... Metabolomic studies generate large and exceptionally complex datasets. The chemical diversity that exists within the metabolome presents an immense analytical challenge. Chemometric methods are frequently used to analyze such data because these approaches offer an efficient route to meaningful interpretation of results. The techniques used in recent research fall into three general categories: sta ...
DOI:
10.1016/j.trac.2020.116165

20. Microneedle based electrochemical (Bio)Sensing: Towards decentralized and continuous health status monitoring

Author:
Juan José García-Guzmán; Clara Pérez-Ràfols; Maria Cuartero; Gaston A. Crespo
Source:
Trends in analytical chemistry 2021 v.135 pp. 116148
ISSN:
0165-9936
Subject:
accuracy; analytical chemistry; assays; biomarkers; blood; calibration; chemical species; electrochemistry; electronics; extraction; glucose; health status; hematologic tests; information sources; laboratories; monitoring; neonates; paper; protocols; publications
Abstract:
... Microneedle (MN) based electrochemical (bio)sensing has become a growing field within the discipline of analytical chemistry as a result of its unique capacity for continuous, decentralized health status monitoring. There are two significant advantages to this exclusive feature: i) the ability to directly analyze interstitial fluid (ISF), a body fluid with a similar enough composition to plasma (a ...
DOI:
10.1016/j.trac.2020.116148