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- Author:
- Muhammad Ovais; Min You; Jalal Ahmad; Ridha Djellabi; Arbab Ali; Mahmood Hassan Akhtar; Manzar Abbas; Chunying Chen
- Source:
- Trends in analytical chemistry 2022 v.153 pp. 116659
- ISSN:
- 0165-9936
- Subject:
- COVID-19 infection; analytical chemistry; biosensors; carbon nanotubes; chemical bonding; distress; early diagnosis; humans; morbidity; pandemic; viruses
- Abstract:
- ... Viral infections have been proven a severe threat to human beings, and the pandemic of Coronavirus Disease 2019 (COVID-19) has become a societal health concern, including mental distress and morbidity. Therefore, the early diagnosis and differentiation of viral infections are the prerequisite for curbing the local and global spread of viruses. To this end, carbon nanotubes (CNTs) based virus detec ...
- DOI:
- 10.1016/j.trac.2022.116659
- https://doi.org/10.1016/j.trac.2022.116659
- Author:
- Xin Wang; Wenxiu Zhou; Zhenye Gao; Xiaoyuan Lv
- Source:
- Trends in analytical chemistry 2022 v.152 pp. 116625
- ISSN:
- 0165-9936
- Subject:
- S-nitrosylation; analytical chemistry; cysteine; humans; mass spectrometry; pathophysiology; proteomics
- Abstract:
- ... Mass spectrometry (MS) has become an indispensable tool in the study of protein identification, protein interactions, and post-translational modifications (PTMs). S-nitrosylation is a major nitric oxide-dependent covalent PTM that targets specific cysteine residues and affects a variety of processes in diverse biological systems. Nowadays, the significance of protein S-nitrosylation in cellular ph ...
- DOI:
- 10.1016/j.trac.2022.116625
- https://doi.org/10.1016/j.trac.2022.116625
- Author:
- Jasvir Kaur; Prabhat K. Singh
- Source:
- Trends in analytical chemistry 2022 v.146 pp. 116483
- ISSN:
- 0165-9936
- Subject:
- analytical chemistry; anions; biochemical pathways; biosensors; humans; nanomaterials
- Abstract:
- ... Inorganic pyrophosphate (PPi) is a crucial anionic analyte that is involved in various biochemical processes of living systems. The deficiency or excess of this anion leads to several abnormalities in humans. Therefore, PPi has drawn significant attention in the last few years from diagnostic point of view. In this regard, a large number of interesting and exciting research reports have emerged th ...
- DOI:
- 10.1016/j.trac.2021.116483
- https://doi.org/10.1016/j.trac.2021.116483
- Author:
- Danilo M. dos Santos; Rafael M. Cardoso; Fernanda L. Migliorini; Murilo H.M. Facure; Luiza A. Mercante; Luiz H.C. Mattoso; Daniel S. Correa
- Source:
- Trends in analytical chemistry 2022 pp. 116672
- ISSN:
- 0165-9936
- Subject:
- analytical chemistry; food analysis; food contamination; food quality; food supply chain; humans; mycotoxins; pesticides; quality control; risk; spoilage; three-dimensional printing
- Abstract:
- ... Food quality control is of utmost importance for human safety and health, requiring efficient and reliable analytical methods for food analysis. The advantageous features as versatility, simplicity, reproducibility, accuracy, and relatively low cost have enabled 3D printing techniques to be employed in the design of portable sensors for the detection of varied food contaminants. This review aims a ...
- DOI:
- 10.1016/j.trac.2022.116672
- https://doi.org/10.1016/j.trac.2022.116672
- Author:
- Albert Pérez-Alcaraz; Francesc Borrull; Marta Calull; Carme Aguilar
- Source:
- Trends in analytical chemistry 2021 v.143 pp. 116347
- ISSN:
- 0165-9936
- Subject:
- analytical chemistry; blood; chromatography; humans; urine
- Abstract:
- ... In recent years, the consumption of synthetic cathinones has grown continuously as these drugs represent a more affordable and obtainable alternative to amphetamines. After consumption, cathinones have a stimulant effect and can be found in the human organism in their pure form or metabolized. As these compounds are difficult to monitor by routine drug screening it is very important to develop pro ...
- DOI:
- 10.1016/j.trac.2021.116347
- https://doi.org/10.1016/j.trac.2021.116347
- Author:
- Bin Hu; Gangfeng Ouyang
- Source:
- Trends in analytical chemistry 2021 v.143 pp. 116368
- ISSN:
- 0165-9936
- Subject:
- analytical chemistry; biomarkers; chemical species; disease diagnosis; environmental health; forensic sciences; human health; human physiology; humans; mass spectrometry; metabolites; solid phase microextraction
- Abstract:
- ... Human samples offer attractive sources for disease diagnosis and biomarker discovery. In situ sampling and analysis of human samples is of paramount importance in the understanding of human physiological and pathological processes that take place in living human objects, and has been applied in various fields, including clinical diagnosis, forensic science, environmental health, biological chemist ...
- DOI:
- 10.1016/j.trac.2021.116368
- https://doi.org/10.1016/j.trac.2021.116368
- Author:
- Maria Eugênia Costa Queiroz; Israel Donizeti de Souza; Igor Gustavo de Oliveira; Caroline Fernandes Grecco
- Source:
- Trends in analytical chemistry 2022 v.153 pp. 116656
- ISSN:
- 0165-9936
- Subject:
- Macaca mulatta; analytical chemistry; bioaccumulation; biomarkers; blood; brain; cattle; chemical species; drugs; environmental monitoring; frogs; humans; ionization; lipidomics; muscles; pharmacokinetics; saliva; solid phase microextraction; therapeutics
- Abstract:
- ... Solid phase microextraction (SPME) is a rapid, well-established, and solvent-free sample preparation technique. It has usually been hyphenated with GC-MS or LC-MS/MS to separate and to detect enriched analytes. In recent years, ambient ionization techniques have been developed fast. This has allowed MS to be used for direct and straightforward SPME analysis of complex samples, dismissing the need ...
- DOI:
- 10.1016/j.trac.2022.116656
- https://doi.org/10.1016/j.trac.2022.116656
- Author:
- Qiang Zeng; Jean-Baptiste Sirven; Jean-Christophe P. Gabriel; Chor Yong Tay; Jong-Min Lee
- Source:
- Trends in analytical chemistry 2021 v.140 pp. 116280
- ISSN:
- 0165-9936
- Subject:
- analytical chemistry; humans; plastics; quantitative analysis
- Abstract:
- ... The huge consumption of modern plastic with improper disposals has posed a great threat to the environment and human beings. To put these post-consumer plastics into the recycling chain, laser induced breakdown spectroscopy (LIBS) has been established as a potential tool for rapid grading of plastics online. Meanwhile, LIBS is a powerful tool for plastic investigations in the laboratory with the c ...
- DOI:
- 10.1016/j.trac.2021.116280
- https://doi.org/10.1016/j.trac.2021.116280
- Author:
- Clementina Vitali; Ruud Peters; Hans-Gerd Janssen; Michel W.F.Nielen
- Source:
- Trends in analytical chemistry 2022 pp. 116670
- ISSN:
- 0165-9936
- Subject:
- agricultural soils; analytical chemistry; data collection; food chain; food safety; humans; marine environment; nanoplastics; risk
- Abstract:
- ... In recent years, the presence of microplastics (MP) and nanoplastics (NP) has been assessed in several environmental matrices, including the marine environment and agricultural soil, suggesting those pollutants are likely to enter the food web. However, there is still a severe lack of information about the occurrence of plastic particles in our food, partially due to the multidimensionality of the ...
- DOI:
- 10.1016/j.trac.2022.116670
- https://doi.org/10.1016/j.trac.2022.116670
- Author:
- Pramod K. Kalambate; Julaluk Noiphung; Nadnudda Rodthongkum; Nutcha Larpant; Pannawich Thirabowonkitphithan; Theerasak Rojanarata; Mohammed Hasan; Yunhui Huang; Wanida Laiwattanapaisal
- Source:
- Trends in analytical chemistry 2021 v.143 pp. 116403
- ISSN:
- 0165-9936
- Subject:
- analytical chemistry; biosensors; detection limit; electrochemistry; electrodes; fever; humans; inflammation; overdose; pain
- Abstract:
- ... Non-steroidal anti-inflammatory drugs (NSAIDs) are the most frequently administered over-the-counter medicines to treat fever, pain and control inflammation. However, their overdose can cause detrimental effects in the human body, whereas uncontrollable disposable into ecosystems pose significant environmental concerns. Electrochemical (bio) sensors overcome the limitations of traditional detectio ...
- DOI:
- 10.1016/j.trac.2021.116403
- https://doi.org/10.1016/j.trac.2021.116403
- Author:
- María Murcia-Morales; Horacio Heinzen; Piedad Parrilla-Vázquez; María del Mar Gómez-Ramos; Amadeo R. Fernández-Alba
- Source:
- Trends in analytical chemistry 2022 v.146 pp. 116506
- ISSN:
- 0165-9936
- Subject:
- analytical chemistry; apiculture; beeswax; chlorpyrifos; dimethoate; fluvalinate; glyphosate; honey; honey bees; humans; imidacloprid; instrumentation; oxalic acid; pollen; pollution; propolis; tebuconazole; thymol
- Abstract:
- ... Pesticide analysis in bee-related matrices is a well-established methodology mainly based on LC-MS/MS and GC-MS/MS instrumentation that allows the determination of the chemical origin of certain colony disorders, as well as the assessment of the environmental contamination and the safety of apicultural products of human interest. The present work approaches this issue from two different perspectiv ...
- DOI:
- 10.1016/j.trac.2021.116506
- https://doi.org/10.1016/j.trac.2021.116506
- Author:
- Bin Hu
- Source:
- Trends in analytical chemistry 2022 v.151 pp. 116600
- ISSN:
- 0165-9936
- Subject:
- COVID-19 infection; air; analytical chemistry; chemical pollutants; environmental exposure; human health; humans; metabolites
- Abstract:
- ... Since the COVID-19 pandemic, the unprecedented use of facemasks has been requiring for wearing in daily life. By wearing facemask, human exhaled breath aerosols and inhaled environmental exposures can be efficiently filtered and thus various filtration residues can be deposited in facemask. Therefore, facemask could be a simple, wearable, in vivo, onsite and noninvasive sampler for collecting exha ...
- DOI:
- 10.1016/j.trac.2022.116600
- https://doi.org/10.1016/j.trac.2022.116600
- Author:
- Yiwei Shi; Ying Cai; Yuhong Cao; Zhanying Hong; Yifeng Chai
- Source:
- Trends in analytical chemistry 2021 v.134 pp. 116118
- ISSN:
- 0165-9936
- Subject:
- analytical chemistry; antineoplastic agents; cell culture; clinical trials; humans; hydrogels; materials; microarray technology; microfluidic technology; models; neoplasms; organ-on-a-chip; prediction; research; screening
- Abstract:
- ... To accelerate the discovery of anti-cancer drugs, there is an urgent need to establish an inexpensive and simple preclinical model that can simulate the tumor microenvironment and screen the drug candidates. Some widely used screening platforms are high-cost and over-simple to verify the cell-drug interactions for predicting human clinical trial outcomes. As a promising technology, microfluidic ch ...
- DOI:
- 10.1016/j.trac.2020.116118
- https://doi.org/10.1016/j.trac.2020.116118
- Author:
- Yanawut Manmana; Takuya Kubo; Koji Otsuka
- Source:
- Trends in analytical chemistry 2021 v.135 pp. 116160
- ISSN:
- 0165-9936
- Subject:
- Coronavirus infections; analytical chemistry; biochemical compounds; case studies; design; developed countries; humans; pandemic; point-of-care systems; researchers; testing
- Abstract:
- ... Point-of-care (POC) testing devices are necessary to improve human life with many aspects both for developing and developed countries. Especially, the specific biomolecules, which are related to particular diseases, are the important targets for POC testing. Recently, many researchers are able to develop POC devices in various platforms and designs due to the discovery and development of new advan ...
- DOI:
- 10.1016/j.trac.2020.116160
- https://doi.org/10.1016/j.trac.2020.116160
- Author:
- U.K. Adarsh; V.B. Kartha; C. Santhosh; V.K. Unnikrishnan
- Source:
- Trends in analytical chemistry 2022 v.149 pp. 116534
- ISSN:
- 0165-9936
- Subject:
- Raman spectroscopy; analytical chemistry; fluorescence emission spectroscopy; humans; industrial wastes; plastics
- Abstract:
- ... 1. The properties of plastics make them highly useful for various purposes in modern life. But the impact of waste produced from the same is raising serious environmental concerns because most of the plastic in use are non-biodegradable. Though there are attempts to develop plastics that are eco-friendly, the production of the same is in the initial stages only. There is thus an urgent need for ef ...
- DOI:
- 10.1016/j.trac.2022.116534
- https://doi.org/10.1016/j.trac.2022.116534
- Author:
- Noelia Caballero-Casero; Lidia Belova; Philippe Vervliet; Jean-Philippe Antignac; Argelia Castaño; Laurent Debrauwer; Marta Esteban López; Carolin Huber; Jana Klanova; Martin Krauss; Arjen Lommen; Hans G.J. Mol; Herbert Oberacher; Olga Pardo; Elliott J. Price; Vera Reinstadler; Chiara Maria Vitale; Alexander L.N. van Nuijs; Adrian Covaci
- Source:
- Trends in analytical chemistry 2021 v.136 pp. 116201
- ISSN:
- 0165-9936
- Subject:
- analytical chemistry; data collection; environmental monitoring; exposome; food analysis; humans; quality control; statistics; terminology; Europe
- Abstract:
- ... Although the exposure assessment of chemicals of emerging concern (CECs) has taken a decisive step forward through advances in (bio)informatics, statistics, and the development of highly sophisticated analytical instruments, the lack of standardisation and harmonisation of analytical workflows and method performance assessment for suspect and non-target screening hampers the interpretation of resu ...
- DOI:
- 10.1016/j.trac.2021.116201
- https://doi.org/10.1016/j.trac.2021.116201
- Author:
- Mariusz Marć; Bożena Zabiegała
- Source:
- Trends in analytical chemistry 2022 v.154 pp. 116669
- ISSN:
- 0165-9936
- Subject:
- adsorption; analytical chemistry; cotton; digestive system; dogs; exposure assessment; humans; respiratory system; risk; silicone; viscose; volatile organic compounds
- Abstract:
- ... The commonly applied solutions used to assess the potential risk of human exposure to semi-volatile organic compounds (SVOCs) are based on the investigation of biological samples collected in an invasive or non-invasive manner. For SVOCs, which are typically introduced to humans through the respiratory system, dermal adsorption, or digestive system, sampling solutions generally used in the indoor ...
- DOI:
- 10.1016/j.trac.2022.116669
- https://doi.org/10.1016/j.trac.2022.116669
- Author:
- Chengjun Sun; Lingli Qu; Ling Wu; Xin Wu; Rui Sun; Yongxin Li
- Source:
- Trends in analytical chemistry 2020 v.127 pp. 115878
- ISSN:
- 0165-9936
- Subject:
- adverse effects; carcinogens; human health; humans; mutagens; physicochemical properties; pollutants; polycyclic aromatic hydrocarbons; toxicity
- Abstract:
- ... Nitrated polycyclic aromatic hydrocarbons (nitro-PAHs) are derivatives of polycyclic aromatic hydrocarbons (PAHs). They are trace pollutants commonly found in the environment and have been widely detected in various matrices. Nitro-PAHs are direct mutagens and carcinogens to humans, so they have attracted increasing public attention. In order to accurately assess the adverse effects of nitro-PAHs ...
- DOI:
- 10.1016/j.trac.2020.115878
- https://doi.org/10.1016/j.trac.2020.115878
- Author:
- Jingjing Yao; Zhongxing Wang; Lingling Guo; Xinxin Xu; Liqiang Liu; Liguang Xu; Shanshan Song; Chuanlai Xu; Hua Kuang
- Source:
- Trends in analytical chemistry 2020 v.131 pp. 116022
- ISSN:
- 0165-9936
- Subject:
- acute toxicity; agriculture; analytical chemistry; antibodies; aquatic organisms; area; detection; extraction; haptens; honey bees; humans; immunoassays; industry; pesticides; pests; public health; pyrethrins; synthesis; water reservoirs
- Abstract:
- ... Organophosphorus (OP) and pyrethroid (PYR) pesticides are widely used to control various vectors and pests in agriculture, multiple industries, public health, green area servicing, and water reservoirs, among others. OP and PYR exposure cause respiratory, myocardial, and neuromuscular impairments in humans and acute toxicity in aquatic organisms and honeybees, respectively. Therefore, rapid, easy, ...
- DOI:
- 10.1016/j.trac.2020.116022
- https://doi.org/10.1016/j.trac.2020.116022
- Author:
- Ana-Maria Dragan; Marc Parrilla; Bogdan Feier; Radu Oprean; Cecilia Cristea; Karolien De Wael
- Source:
- Trends in analytical chemistry 2021 v.145 pp. 116447
- ISSN:
- 0165-9936
- Subject:
- analytical chemistry; human health; humans; law enforcement; markets; mechanism of action; society; toxicology
- Abstract:
- ... This current review focuses on contributions to amphetamine-type substances (ATS) analysis. This type of synthetic illicit drugs has been increasingly present worldwide reaching 5% of the market on illicit drugs in 2019. The increment of their production in many clandestine laboratories and easy distribution among society are two of the main concerns towards the battle against synthetic drugs. The ...
- DOI:
- 10.1016/j.trac.2021.116447
- https://doi.org/10.1016/j.trac.2021.116447
- Author:
- Dorota Turoňová; Lenka Kujovská Krčmová; František Švec
- Source:
- Trends in analytical chemistry 2021 v.143 pp. 116404
- ISSN:
- 0165-9936
- Subject:
- analytical chemistry; forensic sciences; humans; microextraction; solid phase extraction; sorbents; toxicology
- Abstract:
- ... The efficient sample preparation is fundamental in the bioanalysis. Application of solid-phase extraction represents effective sample clean-up and allows final compatibility with selected analytical output. Routine practise desires more efficient and greener approaches. Various μ-solid-phase extraction pipette tips and disposable pipette extraction tips are commercially available. Also, many resea ...
- DOI:
- 10.1016/j.trac.2021.116404
- https://doi.org/10.1016/j.trac.2021.116404
- Author:
- Tutku Beduk; Ceren Durmus; Simge Balaban Hanoglu; Duygu Beduk; Khaled Nabil Salama; Tuncay Goksel; Kutsal Turhan; Suna Timur
- Source:
- Trends in analytical chemistry 2021 v.143 pp. 116329
- ISSN:
- 0165-9936
- Subject:
- analytical chemistry; commercialization; cost effectiveness; diabetes; early diagnosis; gas chromatography; humans; infrared spectroscopy; lung neoplasms; mobile telephones; oxidative stress; point-of-care systems
- Abstract:
- ... Health care monitoring is an enormous field of research that has great potential to solve many problems in human life. In recent years, non-invasive health monitoring has become a prerequisite for early diagnosis of various diseases such as lung cancer, oxidative stress, diabetes, to enable the prompt treatment and screening of crucial chemicals. Although analyzing of exhaled breath has been corre ...
- DOI:
- 10.1016/j.trac.2021.116329
- https://doi.org/10.1016/j.trac.2021.116329
- Author:
- Tahir Rasheed; Adeel Ahmad Hassan; Fahmeeda Kausar; Farooq Sher; Muhammad Bilal; Hafiz M.N. Iqbal
- Source:
- Trends in analytical chemistry 2020 v.132 pp. 116066
- ISSN:
- 0165-9936
- Subject:
- DNA; analytical chemistry; architecture; biodegradability; biosafety; biosensors; carbon nanotubes; commercialization; design; detection; diagnostic techniques; drug delivery systems; ecosystems; gases; glucose; humans; hybrids; monitoring; neoplasm cells; protocols; research; viruses; volatile organic compounds
- Abstract:
- ... The architecture of carbon nanotubes (CNTs) demonstrate phenomenal electronic, mechanical, biological and thermal attributes for highly requisite real-time applications. For instance, electronic and biological features of CNTs are surprisingly striking to engineer robust sensing and/or delivery cues for environmental, analytical diagnostics, and biomedical settings. With CNTs enforcement, several ...
- DOI:
- 10.1016/j.trac.2020.116066
- https://doi.org/10.1016/j.trac.2020.116066
24. Current role of modern chromatography and mass spectrometry in the analysis of mycotoxins in food
- Author:
- Deyber Arley Vargas Medina; João Victor Bassolli Borsatto; Edvaldo Vasconcelos Soares Maciel; Fernando Mauro Lanças
- Source:
- Trends in analytical chemistry 2021 v.135 pp. 116156
- ISSN:
- 0165-9936
- Subject:
- analytical chemistry; carcinogenicity; crops; food matrix; gastrointestinal diseases; humans; ionization; liquid chromatography; mass; mass spectrometry; monitoring; mycotoxins; natural toxicants; nervous system; pesticides; plague; quantitative analysis; sampling; screening; vegetables; veterinary drugs
- Abstract:
- ... The constant surveillance regarding how much safe the food we are intaking has become a critical point in current science since its quality directly affects our health. Several chemicals are used to control plague, diseases, or as health promoters in crops and animals. Although the main classes being controlled are pesticides and veterinary drugs, considerable attention has been targeted to mycoto ...
- DOI:
- 10.1016/j.trac.2020.116156
- https://doi.org/10.1016/j.trac.2020.116156
- Author:
- Aysegul Dogan; Justyna Płotka-Wasylka; Dagmara Kempińska-Kupczyk; Jacek Namieśnik; Agata Kot-Wasik
- Source:
- Trends in analytical chemistry 2020 v.122 pp. 115710
- ISSN:
- 0165-9936
- Subject:
- analytical methods; drug residues; ecosystems; enantiomers; humans; optical isomerism; wastewater
- Abstract:
- ... Chiral pharmaceuticals (CPs) are widely used in different areas of human life, thus they are frequently detected in different ecosystems. However, before CPs reach the environment, wastewater is subjected to different treatment processes in order to remove them. Nevertheless, such processes may affect the chirality of CPs, thus it is very important to monitor CP levels during the wastewater treatm ...
- DOI:
- 10.1016/j.trac.2019.115710
- https://doi.org/10.1016/j.trac.2019.115710
- Author:
- Daniel Blascke Carrão; Icaro Salgado Perovani; Nayara Cristina Perez de Albuquerque; Anderson Rodrigo Moraes de Oliveira
- Source:
- Trends in analytical chemistry 2020 v.122 pp. 115719
- ISSN:
- 0165-9936
- Subject:
- bioaccumulation; enantioselectivity; gas chromatography; humans; liquid chromatography; metabolism; pesticides; soil; supercritical fluid chromatography; toxicity; water pollution
- Abstract:
- ... The potential of chiral pesticides to exhibit stereoselective behavior in regards to activity, toxicity, degradation, bioaccumulation, and/or metabolism has inspired numerous studies, e.g., several works have investigated the contamination of water, food, and soil by chiral pesticides and the consequences of non-targeted species (including human) exposure to these chemicals. As these studies typic ...
- DOI:
- 10.1016/j.trac.2019.115719
- https://doi.org/10.1016/j.trac.2019.115719
- Author:
- Aaron E. Rusheen; Taylor A. Gee; Dong P. Jang; Charles D. Blaha; Kevin E. Bennet; Kendall H. Lee; Michael L. Heien; Yoonbae Oh
- Source:
- Trends in analytical chemistry 2020 v.132 pp. 116049
- ISSN:
- 0165-9936
- Subject:
- Parkinson disease; analytical chemistry; analytical methods; cognition; detection; dopamine; drug abuse; electrochemistry; humans; neurons; quantitative analysis; schizophrenia
- Abstract:
- ... Dysfunction in dopaminergic neuronal systems underlie a number of neurologic and psychiatric disorders such as Parkinson's disease, drug addiction, and schizophrenia. Dopamine systems communicate via two mechanisms, a fast “phasic” release (sub-second to second) that is related to salient stimuli and a slower “tonic” release (minutes to hours) that regulates receptor tone. Alterations in tonic lev ...
- DOI:
- 10.1016/j.trac.2020.116049
- https://doi.org/10.1016/j.trac.2020.116049
- Author:
- Enrique Javier Carrasco-Correa; Julia Ruiz-Allica; Juan Francisco Rodríguez-Fernández; Manuel Miró
- Source:
- Trends in analytical chemistry 2021 v.145 pp. 116446
- ISSN:
- 0165-9936
- Subject:
- absorption; analytical chemistry; biomimetics; blood proteins; humans; intestinal absorption; intestines; lipids; liquid chromatography; permeability; prediction
- Abstract:
- ... Artificial membranes for investigation of the human absorption (oral, dermal or respiratory) of target organic compounds are aimed at mimicking the interactions occurring at and within the cell lipid membrane. Biomolecules such as proteins are also integral components of the lipid membranes and play a pivotal role towards understanding the complex mechanisms of human absorption. In this review, we ...
- DOI:
- 10.1016/j.trac.2021.116446
- https://doi.org/10.1016/j.trac.2021.116446
- Author:
- Yolanda Picó; Damià Barceló
- Source:
- Trends in analytical chemistry 2021 v.145 pp. 116465
- ISSN:
- 0165-9936
- Subject:
- analytical chemistry; biomarkers; epidemiology; humans; wastewater; watersheds
- Abstract:
- ... Wastewater-based epidemiology (WBE) has become popular to estimate the use of drugs of abuse and recently to establish the incidence of CoVID 19 in large cities. However, its possibilities have been expanded recently as a technique that allows to establish a fingerprint of the characteristics of a city, such as state of health/disease, healthy/unhealthy living habits, exposure to different types o ...
- DOI:
- 10.1016/j.trac.2021.116465
- https://doi.org/10.1016/j.trac.2021.116465
- Author:
- Ratnasekhar Ch; Olivier Chevallier; Christopher T. Elliott
- Source:
- Trends in analytical chemistry 2020 v.130 pp. 115986
- ISSN:
- 0165-9936
- Subject:
- Drosophila melanogaster; analytical chemistry; analytical methods; biomarkers; humans; metabolism; metabolites; metabolome; metabolomics; noninsulin-dependent diabetes mellitus; obesity
- Abstract:
- ... Circadian rhythms are a fundamental feature of all organisms from cyanobacteria to humans and govern all aspect of physiology and behaviours. These rhythms exist in individual cells to the entire organism and are driven by cell-autonomous molecular circadian clocks. A significant fraction of cellular metabolome varies according to the time of the day. Disruption of circadian rhythms leads to aberr ...
- DOI:
- 10.1016/j.trac.2020.115986
- https://doi.org/10.1016/j.trac.2020.115986
- Author:
- Yaofeng Zhou; Yuhao Wu; Lu Ding; Xiaolin Huang; Yonghua Xiong
- Source:
- Trends in analytical chemistry 2021 v.145 pp. 116452
- ISSN:
- 0165-9936
- Subject:
- COVID-19 infection; RNA; Severe acute respiratory syndrome coronavirus 2; analytical chemistry; diagnostic techniques; humans; industrialization; pandemic; point-of-care systems; viruses
- Abstract:
- ... Since its first discovery in December 2019, the global coronavirus disease 2019 (COVID-19) pandemic caused by the novel coronavirus (SARS-CoV-2) has been posing a serious threat to human life and health. Diagnostic testing is critical for the control and management of the COVID-19 pandemic. In particular, diagnostic testing at the point of care (POC) has been widely accepted as part of the post re ...
- DOI:
- 10.1016/j.trac.2021.116452
- https://doi.org/10.1016/j.trac.2021.116452
- Author:
- Zhe Feng; Shuyu Ji; Jianfeng Ping; Di Cui
- Source:
- Trends in analytical chemistry 2021 v.143 pp. 116402
- ISSN:
- 0165-9936
- Subject:
- analytical chemistry; antioxidants; chelation; disease diagnosis; ecosystems; edaphic factors; heavy metals; humans; metabolism; metabolites; metabolomics; oxygen; phytoremediation; plant growth; quantitative analysis; toxicology
- Abstract:
- ... Heavy metals (HMs) are affected by natural and human activities and contaminate the soil environment, endanger plant growth and pose a serious threat to the ecosystem. HMs interfere with plant metabolism and some protein activities and cause oxygen stress. Plants combat excess HMs in the environment through a complex array of biological activities (such as antioxidant mechanisms, chelation, and re ...
- DOI:
- 10.1016/j.trac.2021.116402
- https://doi.org/10.1016/j.trac.2021.116402
- Author:
- Ke-Yu Xing; Shan Shan; Dao-Feng Liu; Wei-Hua Lai
- Source:
- Trends in analytical chemistry 2020 v.133 pp. 116087
- ISSN:
- 0165-9936
- Subject:
- analytical chemistry; detection; enzymes; flow; humans; immunoassays; ingestion; luminescence; magnetism; monitoring; mycotoxins; nanoparticles; rapid methods; screening; sensors (equipment); tissues
- Abstract:
- ... Mycotoxins can accumulate in different organs or tissues by ingestion or skin contact and cause several health problems to humans. Thus, developing a rapid detection method for mycotoxins is important. Lateral flow immunoassay (LFI), with outstanding advantages of convenience and rapidity, is especially suitable for on-site monitoring of mycotoxin contamination in food. Some existing LFI have been ...
- DOI:
- 10.1016/j.trac.2020.116087
- https://doi.org/10.1016/j.trac.2020.116087
- Author:
- Jack Rice; Barbara Kasprzyk-Hordern
- Source:
- Trends in analytical chemistry 2019 pp. -
- ISSN:
- 0165-9936
- Subject:
- biomarkers; data collection; environmental monitoring; epidemiology; health effects assessments; humans; illicit drugs; mass spectrometry; models; patients; proteins; proteome; proteomics; public health; surveys; wastewater
- Abstract:
- ... Public health monitoring cannot currently provide real time and comprehensive information about the health of a community as it depends on individual data collection (e.g. surveys) and is limited by the cost of biomonitoring campaigns. To allow for better monitoring of public health the burden of accuracy must move from the participant, whose accuracy cannot always be determined, to an assay or mo ...
- DOI:
- 10.1016/j.trac.2019.115621
- https://doi.org/10.1016/j.trac.2019.115621
- Author:
- Yaser Pashaei; Mona Mehrabi; Maryam Shekarchi
- Source:
- Trends in analytical chemistry 2020 v.130 pp. 115991
- ISSN:
- 0165-9936
- Subject:
- analytical chemistry; cytotoxicity; drug therapy; environmental monitoring; epirubicin; humans; idarubicin; liquid chromatography; metabolites; spectroscopy
- Abstract:
- ... Anthracyclines (ANT), belong to a group of antineoplastic drugs, are commonly used as chemotherapeutic agents in the treatment of various cancers. During the past decade, the number of cancer patients receiving ANT–based chemotherapy drugs has significantly increased. Generally, ANT are very cytotoxic agents and are known to be accompanied by several unpleasant adverse effects. Therefore, the deve ...
- DOI:
- 10.1016/j.trac.2020.115991
- https://doi.org/10.1016/j.trac.2020.115991
- Author:
- Xinglei Yao; Dong Cao; Fengbang Wang; Wenjuan Zhang; Chunyan Ma; Maoyong Song
- Source:
- Trends in analytical chemistry 2019 v.121 pp. 115367
- ISSN:
- 0165-9936
- Subject:
- environmental health; epigenetics; human health; humans; mass spectrometry; metabolomics; microarray technology; nuclear magnetic resonance spectroscopy; perfluorocarbons; proteomics; risk; tissues; transcriptomics; wildlife
- Abstract:
- ... The production and widespread use of perfluoroalkyl substances (PFASs) has led to their presence in the environment, wildlife, and the human body. PFAS exposure has been indicated that could adversely affect human health. PFASs trigger chemical signals to cells, which further emit new signals to tissues and even to organs, and finally cause diseases. Detection of these signals and understanding of ...
- DOI:
- 10.1016/j.trac.2018.12.021
- https://doi.org/10.1016/j.trac.2018.12.021
- Author:
- Justyna Piechocka; Monika Wrońska; Rafał Głowacki
- Source:
- Trends in analytical chemistry 2020 v.126 pp. 115866
- ISSN:
- 0165-9936
- Subject:
- blood; chromatography; clinical examination; cysteine; glutathione; homocysteine; humans; pathogenesis; saliva; thiols; urine
- Abstract:
- ... The number of articles indicating the role of homocysteine and metabolically related compounds, including cysteinyl-glycine, γ-glutamyl-cysteine, cysteine and glutathione, in the pathogenesis of civilization diseases is constantly increasing. Nowadays, blood and urine are the most frequently analyzed biofluids for aminothiols determination. Growing number of people suffering from civilization dise ...
- DOI:
- 10.1016/j.trac.2020.115866
- https://doi.org/10.1016/j.trac.2020.115866
38. Collateral effects of microplastic pollution on aquatic microorganisms: An ecological perspective
- Author:
- Maria Arias-Andres; Keilor Rojas-Jimenez; Hans-Peter Grossart
- Source:
- Trends in analytical chemistry 2019 v.112 pp. 234-240
- ISSN:
- 0165-9936
- Subject:
- antibiotic resistance genes; aquatic ecosystems; biochemical pathways; biofilm; carbon metabolism; ecotoxicology; food webs; horizontal gene transfer; humans; interspersed repetitive sequences; microbial colonization; microbial communities; microbiome; microorganisms; microplastics; organic matter; pathogenicity; pollution
- Abstract:
- ... Microplastics (MP) provide a unique and extensive surface for microbial colonization in aquatic ecosystems. The formation of microorganism-microplastic complexes, such as biofilms, maximizes the degradation of organic matter and horizontal gene transfer. In this context, MP affect the structure and function of microbial communities, which in turn render the physical and chemical fate of MP. This n ...
- DOI:
- 10.1016/j.trac.2018.11.041
- https://doi.org/10.1016/j.trac.2018.11.041
- Author:
- María J. Trujillo-Rodríguez; María Rosende; Manuel Miró
- Source:
- Trends in analytical chemistry 2020 v.132 pp. 116040
- ISSN:
- 0165-9936
- Subject:
- absorption; adhesion; analytical chemistry; animal models; bioassays; bioavailability; cell lines; cytotoxicity; ecotoxicology; estimation; extraction; extracts; gastrointestinal system; humans; risk assessment; sampling; testing; xenobiotics
- Abstract:
- ... In vitro physiologically-based extraction tests (PBETs) play a key role in human risk assessment/exposure of xenobiotics from environmental and food samples. These methods are aimed at determining potential bioaccessible species in the human gastrointestinal tract and, thus, might serve as the first step for correct estimation of average daily intakes in oral exposition studies. However, the use o ...
- DOI:
- 10.1016/j.trac.2020.116040
- https://doi.org/10.1016/j.trac.2020.116040
40. Determination of polycyclic aromatic hydrocarbons in human biological samples: A critical review
- Author:
- Patricia Martín Santos; Miguel del Nogal Sánchez; José Luis Pérez Pavón; Bernardo Moreno Cordero
- Source:
- Trends in analytical chemistry 2019 v.113 pp. 194-209
- ISSN:
- 0165-9936
- Subject:
- blood serum; breast milk; carcinogenicity; cerebrospinal fluid; follicular fluid; humans; placenta; polycyclic aromatic hydrocarbons; saliva; sampling; urine
- Abstract:
- ... Polycyclic aromatic hydrocarbons (PAHs) have raised great concern all over the world due to their carcinogenicity and persistence in nature. Exposure to these analytes can be estimated by determining their concentration in biological matrices, allowing PAH levels in the corresponding samples to be extrapolated to those in the environment. In this article we offer a critical review of the methods u ...
- DOI:
- 10.1016/j.trac.2019.02.010
- https://doi.org/10.1016/j.trac.2019.02.010
- Author:
- Miguel Zea; Francesca G. Bellagambi; Hamdi Ben Halima; Nadia Zine; Nicole Jaffrezic-Renault; Rosa Villa; Gemma Gabriel; Abdelhamid Errachid
- Source:
- Trends in analytical chemistry 2020 v.132 pp. 116058
- ISSN:
- 0165-9936
- Subject:
- analytical chemistry; analytical methods; anti-inflammatory activity; blood pressure; blood serum; carbohydrates; cortisol; detection; electrochemistry; human health; humans; immune system; immunochemistry; metabolism; sampling; sensors (equipment); sweat; technology
- Abstract:
- ... Mostly known as “the stress hormone”, cortisol has many essential functions in humans due to its involvement in regulation of blood pressure, immune system, metabolism of protein, carbohydrate, adipose, and anti-inflammatory action. Since a right cortisol balance is essential for human health, many efforts are currently being made to monitor the cortisol level in the human body. Cortisol levels ar ...
- DOI:
- 10.1016/j.trac.2020.116058
- https://doi.org/10.1016/j.trac.2020.116058
- Author:
- H. Fiedler; I. van der Veen; J. de Boer
- Source:
- Trends in analytical chemistry 2020 v.124 pp. 115459
- ISSN:
- 0165-9936
- Subject:
- air; breast milk; fish; geographical distribution; humans; interleukin-2; monitoring; perfluorocarbons; perfluorooctane sulfonic acid; persistent organic pollutants; sediments; statistical models; Africa; Asia; Caribbean; Europe; Western European region
- Abstract:
- ... The Global Monitoring Plan (GMP) according to article 16 of the Stockholm Convention on Persistent Organic Pollutants (POPs) requires that POP laboratories must be capable – at any time – to analyse samples for POPs within a variation of ±25%. Based on this target error of 25%, a statistical model using z-scores was applied to assess the performance of analytical laboratories for POPs and a number ...
- DOI:
- 10.1016/j.trac.2019.03.023
- https://doi.org/10.1016/j.trac.2019.03.023
- Author:
- Si Ying Lim; Bao Hui Ng; Sam F.Y. Li
- Source:
- Trends in analytical chemistry 2020 v.133 pp. 116084
- ISSN:
- 0165-9936
- Subject:
- age; alcohol abuse; analytical chemistry; bioinformatics; biomarkers; blood; blood sampling; crime; experts; forensic sciences; gender; glycomics; glycosylation; harvesting; humans; information; lifestyle; nationalities and ethnic groups; polysaccharides; research; risk; scientists; smoking (habit)
- Abstract:
- ... Research thus far has ascertained the potential of glycans as biomarkers of disease. Recent developments in glycan analysis also suggests connections between glycosylation traits and physiological states as well as lifestyle habits. The trends in recent reports thus allowed us to discern the applicability of harvesting glycomic information from one of the most common crime scene evidence – blood. ...
- DOI:
- 10.1016/j.trac.2020.116084
- https://doi.org/10.1016/j.trac.2020.116084
- Author:
- Paul T.J. Scheepers; John Cocker
- Source:
- Trends in analytical chemistry 2019 v.113 pp. 116-123
- ISSN:
- 0165-9936
- Subject:
- bioavailability; biomarkers; blood; environmental exposure; environmental monitoring; health effects assessments; human health; humans; lungs; mass spectrometry; metabolites; tissues; toxicity; urine; xenobiotics
- Abstract:
- ... The analysis of body tissues for xenobiotics from occupational and environmental exposures is a rapidly growing field with much societal impact. This use of biomarkers, outside the clinical setting, is referred to as biomonitoring. It informs human health risk assessment by providing information on uptake, bioavailability and bio-activation. Some toxic species are analyzed in tissues of first cont ...
- DOI:
- 10.1016/j.trac.2019.02.001
- https://doi.org/10.1016/j.trac.2019.02.001
- Author:
- Jing Xu; Qin-Feng Zhang; Jie Zheng; Bi-Feng Yuan; Yu-Qi Feng
- Source:
- Trends in analytical chemistry 2019 v.112 pp. 161-174
- ISSN:
- 0165-9936
- Subject:
- absorption; capillary electrophoresis; carcinogenesis; diet; digestion; feces; gas chromatography-mass spectrometry; homeostasis; human health; human physiology; humans; ingestion; intestinal microorganisms; intestines; lifestyle; liquid chromatography; metabolites; metabolome; metabolomics; symbiosis
- Abstract:
- ... The past decade has witnessed remarkable progress in our understanding of the important roles that gut microbial metabolites play in modulating the human health. The dynamic interplay between the host and gut microbiota is critical for maintaining the host homeostasis. The gut microbial metabolites are increasingly being recognized as an important part of human physiology. The symbiosis between hu ...
- DOI:
- 10.1016/j.trac.2018.12.027
- https://doi.org/10.1016/j.trac.2018.12.027
- Author:
- Chang Tian; Qin Tu; Wenming Liu; Jinyi Wang
- Source:
- Trends in analytical chemistry 2019 v.117 pp. 146-156
- ISSN:
- 0165-9936
- Subject:
- biomimetics; cytokines; humans; microfluidic technology; nutrients; organ-on-a-chip; paper; physiology; spinning; tissue engineering; wastes
- Abstract:
- ... Organ-on-a-chip (OOC) systems were developed by combining microfluidic technologies and tissue engineering to mimic physiological conditions in the body. OOC systems can recreate key aspects of the complex human physiological microenvironment, such as critical tissue interfaces; spatiotemporal cell–cell/extracellular matrix interactions; and concentration gradients involving nutrients, metabolic w ...
- DOI:
- 10.1016/j.trac.2019.06.005
- https://doi.org/10.1016/j.trac.2019.06.005
- Author:
- Wojciech Filipiak; Barbara Bojko
- Source:
- Trends in analytical chemistry 2019 v.115 pp. 203-213
- ISSN:
- 0165-9936
- Subject:
- antibiotic resistance; biomarkers; biomedical research; diagnostic techniques; human cell lines; humans; in vitro studies; industry; medicine; metabolome; models; new drugs; solid phase microextraction
- Abstract:
- ... Growing threats in modern medicine, e.g., antibiotic resistance, along with urgent need for rapid diagnostic techniques and introduction of new drugs, induced intensive clinical and basic research. Model in vitro experiments with bacteria cultures and human cell lines, ex vivo experiments with tissues and in vivo animal or human study put more light into mechanism of cellular processes and biomark ...
- DOI:
- 10.1016/j.trac.2019.02.029
- https://doi.org/10.1016/j.trac.2019.02.029
- Author:
- Bruce Petrie; Maria Dolores Camacho Muñoz; Julia Martín
- Source:
- Trends in analytical chemistry 2019 v.110 pp. 249-258
- ISSN:
- 0165-9936
- Subject:
- analytical chemistry; environmental assessment; humans; liquid chromatography; monitoring; pesticides; stereoselectivity; tandem mass spectrometry; toxicity
- Abstract:
- ... Chiral pesticides can exert stereospecific toxicity in contaminated environmental compartments. Therefore, measuring pesticides at the enantiomeric level is essential to assess the risk posed to exposed organisms, including humans. In recent years, there has been rapid progress on the development and application of stereoselective liquid chromatography–tandem mass spectrometry (LC–MS/MS) methodolo ...
- DOI:
- 10.1016/j.trac.2018.11.010
- https://doi.org/10.1016/j.trac.2018.11.010
- Author:
- Ning Yi; Mingzhou Shen; Daniel Erdely; Huanyu Cheng
- Source:
- Trends in analytical chemistry 2020 v.133 pp. 116085
- ISSN:
- 0165-9936
- Subject:
- analytical chemistry; biomarkers; deformation; design; detection; environment; humans; nanoparticles; nanowires; serpentine; thickness; toxicity
- Abstract:
- ... The recent advent of stretchable gas sensors demonstrates their capabilities to detect not only gaseous biomarkers from the human body but also toxic gas species from the exposed environment. To ensure accurate gas detection without device breakdown from the mechanical deformations, the stretchable gas sensors often rely on the direct integration of gas-sensitive nanomaterials on the stretchable s ...
- DOI:
- 10.1016/j.trac.2020.116085
- https://doi.org/10.1016/j.trac.2020.116085
- Author:
- Rachel Rui Xia Lim; Alessandra Bonanni
- Source:
- Trends in analytical chemistry 2020 v.133 pp. 116081
- ISSN:
- 0165-9936
- Subject:
- Orthocoronavirinae; administrative management; analytical chemistry; antibodies; antigens; detection; diagnostic techniques; electrochemistry; environment; etiology; gold; humans; pandemic; point-of-care systems; portable equipment; respiratory tract diseases; strains; therapeutics; viruses
- Abstract:
- ... Human coronaviruses (HCoV) are no stranger to the global environment. The etiology of previous outbreaks with reported symptoms of respiratory tract infections was attributed to different coronavirus strains, with the latest global pandemic in 2019 also belonging to the coronavirus family. Timely detection, effective therapeutics and future prevention are stake key holders in the management of cor ...
- DOI:
- 10.1016/j.trac.2020.116081
- https://doi.org/10.1016/j.trac.2020.116081
- Author:
- Patrick Cesar Ferreira; Vanessa Neiva Ataíde; Cyro Lucas Silva Chagas; Lúcio Angnes; Wendell Karlos Tomazelli Coltro; Thiago Regis Longo Cesar Paixão; William Reis de Araujo
- Source:
- Trends in analytical chemistry 2019 pp. -
- ISSN:
- 0165-9936
- Subject:
- biomarkers; chemical species; electrochemistry; extracellular fluids; forensic sciences; health status; humans; monitoring; saliva; sensors (equipment); sweat; tears; toxic substances
- Abstract:
- ... Electrochemical sensors are powerful analytical tools that, in the last few years, have attracted tremendous attention in coupling with wearable devices due to their incomparable properties, such as instrumental simplicity, low cost, flexibility, and miniaturization. These outstanding characteristics fit with the desired features for continuous on-body analyses. Wearable electrochemical sensors en ...
- DOI:
- 10.1016/j.trac.2019.115622
- https://doi.org/10.1016/j.trac.2019.115622
- Author:
- M. Oliveira; M. Almeida; I. Miguel
- Source:
- Trends in analytical chemistry 2019 v.112 pp. 196-200
- ISSN:
- 0165-9936
- Subject:
- air; beverages; exposure pathways; food contamination; humans; microplastics; water currents; wind
- Abstract:
- ... Plastics are an integral but largely inconspicuous part of human daily routines. Associated with a high production and single use nature of several products, small plastic particles became ubiquitous. Due to processes like water currents and winds, plastics may occur far from their place of origin and affect biota at different environmental compartments. In the environment plastics can degrade int ...
- DOI:
- 10.1016/j.trac.2019.01.005
- https://doi.org/10.1016/j.trac.2019.01.005
- Author:
- Francisca Ribeiro; Jake W. O'Brien; Tamara Galloway; Kevin V. Thomas
- Source:
- Trends in analytical chemistry 2019 v.111 pp. 139-147
- ISSN:
- 0165-9936
- Subject:
- aquatic invertebrates; birds; environmental impact; humans; insects; marine mammals; mechanism of action; nanoplastics; sea turtles; tissues
- Abstract:
- ... Following a decade of research on the environmental impacts of microplastics, a knowledge gap remains on the processes by which micro and nanoplastics pass across biological barriers, enter cells and are subject to biological mechanisms. Here we summarize available literature on the accumulation of microplastics and their associated contaminants in a variety of organisms including humans. Most dat ...
- DOI:
- 10.1016/j.trac.2018.12.010
- https://doi.org/10.1016/j.trac.2018.12.010
- Author:
- Vahid Shafiei-Irannejad; Jafar Soleymani; Sajjad Azizi; Maryam KhoubnasabJafari; Abolghasem Jouyban; Mohammad Hasanzadeh
- Source:
- Trends in analytical chemistry 2019 v.116 pp. 1-12
- ISSN:
- 0165-9936
- Subject:
- analytical methods; biosensors; blood glucose; carbon; diabetes; electrochemistry; gold; humans; insulin; insulin secretion; magnetism; myocardial infarction; nanogold; nanosilver; neurodegenerative diseases; obesity; peptide hormones; point-of-care systems; polymers; quartz crystal microbalance; renal failure; silver
- Abstract:
- ... Insulin is one of the most important peptide hormones with a critical role in the control of human blood glucose level. Any changes in insulin secretion level can be resulted in various diseases including diabetes, kidney failure, obesity, neurodegenerative disease and myocardial infarctions. Thus, ultrasensitive and specific recognition of insulin is crucial for early stage diagnosis and treatmen ...
- DOI:
- 10.1016/j.trac.2019.04.020
- https://doi.org/10.1016/j.trac.2019.04.020
- Author:
- Maolin Tu; Shuzhen Cheng; Weihong Lu; Ming Du
- Source:
- Trends in analytical chemistry 2018 v.105 pp. 7-17
- ISSN:
- 0165-9936
- Subject:
- bioinformatics; chronic diseases; functional foods; health promotion; humans; ingredients; metabolism; peptides; toxicity
- Abstract:
- ... Food-derived bioactive peptides, as potential ingredients in health-promoting functional foods targeting diet-related chronic diseases, have attracted increasing attention because of their high biological activities, low toxicity, and easy of metabolism in human body. However, conventional methods for analyzing the bioactive peptides are not only expensive but also time-consuming; these drawbacks ...
- DOI:
- 10.1016/j.trac.2018.04.005
- https://doi.org/10.1016/j.trac.2018.04.005
56. Carbon based nanomaterials - A promising electrochemical sensor toward persistent toxic substance
- Author:
- Feng Xie; Meng Yang; Min Jiang; Xing-Jiu Huang; Wen-Qing Liu; Pin-Hua Xie
- Source:
- Trends in analytical chemistry 2019 pp. -
- ISSN:
- 0165-9936
- Subject:
- carbon nanotubes; detection limit; electrochemistry; electrodes; graphene; humans; sensors (equipment); surface area; toxicity
- Abstract:
- ... Persistent toxic substance (PTS) poses a great threat to the ecological environment and human beings because of its difficult degradation and strong toxicity. Therefore, developing a safe and simple method to detect PTS is significance. Among many detection methods, the electrochemical method shows a lot of advantages, including high sensitivity, low limit of detection (LOD) and low cost. Meanwhil ...
- DOI:
- 10.1016/j.trac.2019.115624
- https://doi.org/10.1016/j.trac.2019.115624
- Author:
- B. Gruber; B.A. Weggler; R. Jaramillo; K.A. Murrell; P.K. Piotrowski; F.L. Dorman
- Source:
- Trends in analytical chemistry 2018 v.105 pp. 292-301
- ISSN:
- 0165-9936
- Subject:
- comprehensive two-dimensional gas chromatography; data collection; forensic sciences; humans; information processing; odors; processing technology
- Abstract:
- ... Comprehensive two-dimensional gas chromatography (GC × GC) has become accepted as one of the most powerful separation techniques in several application areas. In forensic investigations, however, it has not yet been entirely established due to limitations regarding standardized methodology, data interpretation and consistency of results. Nevertheless, GC × GC allows for target analysis, compound c ...
- DOI:
- 10.1016/j.trac.2018.05.017
- https://doi.org/10.1016/j.trac.2018.05.017
- Author:
- Pramod K. Kalambate; Dhanjai; Zhimei Huang; Yankai Li; Yue Shen; Meilan Xie; Yunhui Huang; Ashwini K. Srivastava
- Source:
- Trends in analytical chemistry 2019 v.115 pp. 147-161
- ISSN:
- 0165-9936
- Subject:
- deformation; food analysis; humans; monitoring; nanomaterials; sensors (equipment); surface area
- Abstract:
- ... Core-shell nanomaterials (CSNs) have achieved huge popularity due to multifunctional properties achieved by manipulation of core or shell materials. This review highlights recent development in CSNs based sensing devices such as electrochemical sensors, optical sensors, wearable sensing devices, and gas adsorptive sensors, which find potential applications in numerous fields ranging from industria ...
- DOI:
- 10.1016/j.trac.2019.04.002
- https://doi.org/10.1016/j.trac.2019.04.002
- Author:
- Alicia Robles; Magdalena Fabjanowicz; Tomasz Chmiel; Justyna Płotka-Wasylka
- Source:
- Trends in analytical chemistry 2019 pp. -
- ISSN:
- 0165-9936
- Subject:
- acidity; aesthetics; analytical methods; anti-inflammatory activity; antioxidant activity; humans; organic acids and salts; winemaking; wines
- Abstract:
- ... For long time, organic acids were underestimated. However, during last two decades there is an increasing interest of natural compounds having antioxidant, antimicrobial and anti-inflammatory properties thus organic acids are very preferable. Wine stands as one of the sources of organic acids since they are responsible for its organoleptic and aesthetic character. Nevertheless, it is important to ...
- DOI:
- 10.1016/j.trac.2019.115630
- https://doi.org/10.1016/j.trac.2019.115630
- Author:
- Andrew D. Turner; Robert G. Hatfield; Benjamin H. Maskrey; Myriam Algoet; Jim F. Lawrence
- Source:
- Trends in analytical chemistry 2019 v.113 pp. 124-139
- ISSN:
- 0165-9936
- Subject:
- European Union; bioassays; chromatography; health promotion; humans; mice; monitoring; oxidation; paralytic shellfish poisoning; quality control; saxitoxins; screening; shellfish
- Abstract:
- ... Naturally-occurring saxitoxins periodically accumulate in shellfish giving rise to Paralytic Shellfish Poisoning. For decades a mouse bioassay has been used for public health protection, but in 2019 a pre-column oxidation LC-FLD method became the official reference method in the European Union. Laboratories are now required to use this method for regulatory monitoring, which will prove challenging ...
- DOI:
- 10.1016/j.trac.2019.02.005
- https://doi.org/10.1016/j.trac.2019.02.005
- Author:
- Li Zhang; Dong Peng; Ru-Ping Liang; Jian-Ding Qiu
- Source:
- Trends in analytical chemistry 2018 v.102 pp. 280-289
- ISSN:
- 0165-9936
- Subject:
- biosensors; graphene; graphene oxide; heavy metals; humans; metal ions; pollution; quantum dots
- Abstract:
- ... Heavy metal ion pollution has threatened environmental and human safety. Therefore, there is a remarkable demand to detect heavy metal ions in a fast, sensitive, and selective way. Although conventional sensors have been designed and widely applied in heavy metal ion determination, they present many limitations and challenges. Graphene-based nanotechnology overcomes these challenges and endows the ...
- DOI:
- 10.1016/j.trac.2018.02.010
- https://doi.org/10.1016/j.trac.2018.02.010
- Author:
- Yanna Liu; Lisa A. D'Agostino; Guangbo Qu; Guibin Jiang; Jonathan W. Martin
- Source:
- Trends in analytical chemistry 2019 v.121 pp. 115420
- ISSN:
- 0165-9936
- Subject:
- fluorine; hazard characterization; humans; mass spectrometry; monitoring; pollution
- Abstract:
- ... Widespread environmental contamination of legacy long-chain poly- and per-fluoroalkyl substances (PFASs) has triggered chemical regulatory action and a global transitioning to alternative PFASs. More than 5000 PFASs are now recognized on various lists, but few have been monitored despite ample evidence of unidentified organic fluorine in human and environmental samples. Nevertheless, our review of ...
- DOI:
- 10.1016/j.trac.2019.02.021
- https://doi.org/10.1016/j.trac.2019.02.021
- Author:
- Christian W. Klampfl
- Source:
- Trends in analytical chemistry 2019 v.111 pp. 13-26
- ISSN:
- 0165-9936
- Subject:
- biosolids; drug residues; environmental assessment; fertilizers; humans; irrigation; metabolites; sewage treatment; soil
- Abstract:
- ... Residues of pharmaceuticals are ubiquitous in the environment, due to the increased use of drugs for treating humans and animals. If in agriculture water or biosolids from sewage treatment plants or manure from treated animals are used for irrigation or as a fertilizer respectively, drug residues may come into contact with plants. Subsequently these substances may be taken up, be translocated and ...
- DOI:
- 10.1016/j.trac.2018.11.042
- https://doi.org/10.1016/j.trac.2018.11.042
- Author:
- Huaying Chen; Zhihang Yu; Siwei Bai; Huaxiu Lu; Dong Xu; Chang Chen; Di Liu; Yonggang Zhu
- Source:
- Trends in analytical chemistry 2019 v.117 pp. 186-199
- ISSN:
- 0165-9936
- Subject:
- cell biology; cell culture; drug development; exposure duration; humans; image analysis; microfluidic technology; microscopy; models; shear stress
- Abstract:
- ... Shear stress of physiological flows in the human body plays a critical role in maintaining the structure and functions of single cells and multicellular organs. Recently, the wide-spreading microfluidic technologies have made significant contributions to the in-vitro recapitulation of complex biochemical and mechanical cues. Microfluidic approaches are of inherent advantages in modeling of flow sh ...
- DOI:
- 10.1016/j.trac.2019.06.023
- https://doi.org/10.1016/j.trac.2019.06.023
- Author:
- Paul Miggiels; Bert Wouters; Gerard J.P. van Westen; Anne-Charlotte Dubbelman; Thomas Hankemeier
- Source:
- Trends in analytical chemistry 2018 pp. -
- ISSN:
- 0165-9936
- Subject:
- automation; biomarkers; cohort studies; computer software; humans; mass spectrometry; metabolome; metabolomics; nuclear magnetic resonance spectroscopy; precision medicine; prediction
- Abstract:
- ... The human metabolome provides a direct physiological read-out of an individual's actual health state and includes biomarkers that may predict disease or response to a treatment. The discovery and validation of these metabolomic biomarkers requires large-scale cohort studies, typically involving thousands of samples. This analytical challenge drives novel technological developments to enable faster ...
- DOI:
- 10.1016/j.trac.2018.11.021
- https://doi.org/10.1016/j.trac.2018.11.021
- Author:
- Li Zhang; Xiao-Rong Chen; Shao-Hua Wen; Ru-Ping Liang; Jian-Ding Qiu
- Source:
- Trends in analytical chemistry 2019 v.118 pp. 869-879
- ISSN:
- 0165-9936
- Subject:
- arsenates; arsenic; arsenites; colorimetry; fluorometry; humans; nanomaterials
- Abstract:
- ... The measurement of arsenic has received considerable attention due to its contaminant to environment and harm on human safety. This paper provides an overview of optical methods on the measurement of inorganic arsenic (arsenite and arsenate). We present and discuss the colorimetric, scattering, and fluorimetric strategies for inorganic arsenic detection based on the organic/biological molecules an ...
- DOI:
- 10.1016/j.trac.2019.07.013
- https://doi.org/10.1016/j.trac.2019.07.013
- Author:
- Daming Dong; Leizi Jiao; Chuanxia Li; Chunjiang Zhao
- Source:
- Trends in analytical chemistry 2019 v.110 pp. 410-416
- ISSN:
- 0165-9936
- Subject:
- biomarkers; biomedical research; food processing; food quality; gas chromatography-mass spectrometry; gases; humans; metabolomics; monitoring; patients; volatile compounds
- Abstract:
- ... The analysis of gases exhaled in human breath is of great interest in medical research for assessing patient health. Foods also ‘breathe’, releasing volatile compounds whose composition and concentration can indicate the properties of the food. Recently, food metabolomics has seen rapid development, with advanced methods, such as GC-MS, used to analyze volatiles and identify biomarkers. On the con ...
- DOI:
- 10.1016/j.trac.2018.11.039
- https://doi.org/10.1016/j.trac.2018.11.039
- Author:
- Yueyao Zhang; Guoliang Li; Di Wu; Xiuting Li; Yanxin Yu; Pengjie Luo; Jian Chen; Chunji Dai; Yongning Wu
- Source:
- Trends in analytical chemistry 2019 v.121 pp. 115669
- ISSN:
- 0165-9936
- Subject:
- coordination compounds; food matrix; food safety; foods; humans; molecular imprinting; nanomaterials; public health; quantitative analysis
- Abstract:
- ... Food safety has been a global public health concern. Humans are seriously endangered by numerous contaminants in foodstuffs. Owning to the complexity of food matrices, sample pretreatment is an essential step both in qualitative and quantitative analysis of trace contaminants. Thus, the effective food pretreatment method is of great importance. Recently, development of nanomaterials has greatly pr ...
- DOI:
- 10.1016/j.trac.2019.115669
- https://doi.org/10.1016/j.trac.2019.115669
- Author:
- Shuo Yin; Yi Yang; Ling Wu; Yongxin Li; Chengjun Sun
- Source:
- Trends in analytical chemistry 2019 v.110 pp. 204-220
- ISSN:
- 0165-9936
- Subject:
- absorption; analytical methods; biochemical pathways; bone metabolism; calcium; chronic diseases; developed countries; drugs; foods; humans; metabolism; musculoskeletal diseases; nutritional status; phosphates; quality control; risk; vitamin D; vitamin D deficiency
- Abstract:
- ... Vitamin D plays an important role in decreasing the risk of various musculoskeletal diseases and chronic illnesses by participating in the calcium, phosphate absorption, bone metabolism and many other metabolic pathways. Vitamin D deficiency among populations of different ages is common throughout the world, even in the developed countries. Accurate vitamin D analysis is crucial for quality contro ...
- DOI:
- 10.1016/j.trac.2018.11.008
- https://doi.org/10.1016/j.trac.2018.11.008
70. Recent developments in carbon nanomaterial-enabled electrochemical sensors for nitrite detection
- Author:
- Xunjia Li; Jianfeng Ping; Yibin Ying
- Source:
- Trends in analytical chemistry 2019 v.113 pp. 1-12
- ISSN:
- 0165-9936
- Subject:
- carbon nanofibers; carbon nanotubes; graphene; graphene oxide; human health; humans; nanodiamonds; nanopores; nitrites; sensors (equipment); toxicity
- Abstract:
- ... Nitrite is widely found in the natural environment and human life, but the abuse and potential toxicity of nitrite poses a great threat to human health. Therefore, it is necessary to develop effective, robust, and reliable methods for nitrite detection. Carbon nanomaterials have shown their great potential in the development of high-performance electrochemical sensors in view of their numerous fas ...
- DOI:
- 10.1016/j.trac.2019.01.008
- https://doi.org/10.1016/j.trac.2019.01.008
- Author:
- Allison J. Levy; Nicholas R. Oranzi; Atiye Ahmadireskety; Robin H.J. Kemperman; Michael S. Wei; Richard A. Yost
- Source:
- Trends in analytical chemistry 2019 v.116 pp. 274-281
- ISSN:
- 0165-9936
- Subject:
- chromatography; desorption; disease progression; humans; image analysis; instrumentation; ionization; isomers; lipids; metabolites; metabolomics; spectroscopy
- Abstract:
- ... In recent years, metabolomics and lipidomics approaches have become increasingly popular for use in the analysis of human heath, molecular mechanisms, and disease progression. Despite the growth in applications and advances in instrumentation, metabolomics and lipidomics are limited by factors including interference from matrix effects, the need for lengthy for chromatographic analysis, and struct ...
- DOI:
- 10.1016/j.trac.2019.05.001
- https://doi.org/10.1016/j.trac.2019.05.001
- Author:
- Reza Eivazzadeh-Keihan; Paria Pashazadeh-Panahi; Behzad Baradaran; Miguel de la Guardia; Maryam Hejazi; Hessamaddin Sohrabi; Ahad Mokhtarzadeh; Ali Maleki
- Source:
- Trends in analytical chemistry 2018 v.103 pp. 184-197
- ISSN:
- 0165-9936
- Subject:
- Clostridium botulinum; acetylcholine; biosensors; botulinum toxin; botulism; cost effectiveness; diagnostic techniques; electrochemistry; enzyme activity; humans; monitoring; nerve tissue; neurotoxicity; paralysis; synapse
- Abstract:
- ... Botulinum toxin is a neurotoxic protein which produced from Clostridium botulinum and related species and it block acetylcholine release from presynaptic nerve terminals at the neuromuscular junctions. This toxin is life threatening for millions of people and growing menace to society since causing human botulism. Enzymatic activity of Botulinum neurotoxin within the cell made it hazardous and lea ...
- DOI:
- 10.1016/j.trac.2018.03.019
- https://doi.org/10.1016/j.trac.2018.03.019
73. Recent progress in the sensing techniques for the detection of human thyroid stimulating hormone
- Author:
- Rajesh; Krishan Kumar; Sujeet K. Mishra; Poonam Dwivedi; Gajjala Sumana
- Source:
- Trends in analytical chemistry 2019 v.118 pp. 666-676
- ISSN:
- 0165-9936
- Subject:
- biosensors; blood serum; commercialization; eyes; heart rate; humans; hyperthyroidism; hypothyroidism; infants; neoplasms; thyrotropin
- Abstract:
- ... Thyroid-stimulating hormone (TSH) protein in the human serum is considered as a most sensitive indicator for the diagnosis of several diseases related to hyperthyroidism and hypothyroidism. Hypothyroidism due to high TSH levels cause pituitary tumors, congenital hypothyroidism in infants and chronic lymphatic thyroiditis, whereas hyperthyroidism caused by low TSH levels lead to rapid and irregular ...
- DOI:
- 10.1016/j.trac.2019.06.033
- https://doi.org/10.1016/j.trac.2019.06.033
- Author:
- Małgorzata Rutkowska; Justyna Płotka-Wasylka; Tomasz Majchrzak; Wojciech Wojnowski; Hanna Mazur-Marzec; Jacek Namieśnik
- Source:
- Trends in analytical chemistry 2019 v.112 pp. 112-122
- ISSN:
- 0165-9936
- Subject:
- action potentials; analytical methods; anatoxins; aquatic ecosystems; ciguatoxin; humans; isomers; nervous system; neurotoxins; saxitoxins
- Abstract:
- ... Anatoxins, saxitoxins, ciguatoxins, beta-N-methylamino-l-alanine and its isomers are groups of neurotoxins which have a highly specific effect on the nervous system of animals, including humans, by interfering with the transmission of nerve impulses. In order to assess the human exposure to these neurotoxins, selective, interlaboratory-validated analytical methods are being developed to facilitate ...
- DOI:
- 10.1016/j.trac.2019.01.001
- https://doi.org/10.1016/j.trac.2019.01.001
- Author:
- Rita Triebskorn; Thomas Braunbeck; Tamara Grummt; Lisa Hanslik; Sven Huppertsberg; Martin Jekel; Thomas P. Knepper; Stefanie Krais; Yanina K. Müller; Marco Pittroff; Aki S. Ruhl; Hannah Schmieg; Christoph Schür; Claudia Strobel; Martin Wagner; Nicole Zumbülte; Heinz-R. Köhler
- Source:
- Trends in analytical chemistry 2019 v.110 pp. 375-392
- ISSN:
- 0165-9936
- Subject:
- freshwater; freshwater ecosystems; humans; nanoplastics; rivers; toxicity
- Abstract:
- ... The current paper critically reviews the state-of-the-science on (1) microplastics (MP) types and particle concentrations in freshwater ecosystems, (2) MP and nanoplastics (NP) uptake and tissue translocation, (3) MP/NP-induced effects in freshwater organisms, and (4) capabilities of MP/NP to modulate the toxicity of environmental chemicals. The reviewed literature as well as new data on MP and NP ...
- DOI:
- 10.1016/j.trac.2018.11.023
- https://doi.org/10.1016/j.trac.2018.11.023
- Author:
- Tomasz Majchrzak; Wojciech Wojnowski; Grażyna Piotrowicz; Jacek Gębicki; Jacek Namieśnik
- Source:
- Trends in analytical chemistry 2018 v.108 pp. 38-49
- ISSN:
- 0165-9936
- Subject:
- best available technology; diagnostic techniques; digestive system diseases; headspace analysis; humans; volatile organic compounds
- Abstract:
- ... The analysis of the human volatilome can be successfully used for rapid and non-invasive diagnostics of gastrointestinal diseases. However, the introduction of techniques based on detection of volatiles is limited, among other factors, by difficulties which arise during the sampling stage and instrumental analysis. The aim of this article was to review and discuss medical and analytical literature ...
- DOI:
- 10.1016/j.trac.2018.08.020
- https://doi.org/10.1016/j.trac.2018.08.020
- Author:
- Vishal Sharma; Raj Kumar
- Source:
- Trends in analytical chemistry 2018 v.107 pp. 181-195
- ISSN:
- 0165-9936
- Subject:
- analytical methods; blood; chemometrics; crime; forensic sciences; humans; models; multivariate analysis
- Abstract:
- ... The potential to ascertain the origin and aging of bloodstains have various important applications in the forensic serological investigation. The individualization of bloodstain is necessary as both human and animals can be involved in the crimes. The foremost advantages of these types of investigation are: the expert significantly differentiates between human and animal blood which ultimately hel ...
- DOI:
- 10.1016/j.trac.2018.08.006
- https://doi.org/10.1016/j.trac.2018.08.006
- Author:
- Phil M. Choi; Ben J. Tscharke; Erica Donner; Jake W. O'Brien; Sharon C. Grant; Sarit L. Kaserzon; Rachel Mackie; Elissa O'Malley; Nicholas D. Crosbie; Kevin V. Thomas; Jochen F. Mueller
- Source:
- Trends in analytical chemistry 2018 v.105 pp. 453-469
- ISSN:
- 0165-9936
- Subject:
- alcohol drinking; antibiotic resistance; biomarkers; drug therapy; epidemiology; human health; humans; illicit drugs; infectious diseases; pathogens; smoking (habit); tobacco; wastewater; watersheds
- Abstract:
- ... Wastewater is a complex matrix containing a wide range of chemical and biological markers of human activity. Relating concentrations of these “waste” materials in wastewater influent streams to population-scale use, consumption, or rates of exposure, can provide important qualitative or quantitative information on the activity of inhabitants within a given wastewater catchment. Many publications i ...
- DOI:
- 10.1016/j.trac.2018.06.004
- https://doi.org/10.1016/j.trac.2018.06.004
79. Analysis of emerging contaminants and nanomaterials in plant materials following uptake from soils
- Author:
- Yolanda Picó; Ahmed Alfarham; Damià Barceló
- Source:
- Trends in analytical chemistry 2017 v.94 pp. 173-189
- ISSN:
- 0165-9936
- Subject:
- European Union; analytical methods; biochar; biosolids; climate change; engineering; food chain; humans; irrigation water; nanomaterials; particle size distribution; river water; soil; soil amendments; wastewater
- Abstract:
- ... The reuse of treated wastewater or wastewater-impacted river water is growing, particularly in arid areas, due to the climate change. As well, the disposal of sludges, biosolids or biochar as soil amendments to improve agricultural output is widely implemented in the EU. These practices can be a source of emerging contaminants and engineering nanomaterials (ENMs) to the environment and condition t ...
- DOI:
- 10.1016/j.trac.2017.07.016
- https://doi.org/10.1016/j.trac.2017.07.016
- Author:
- Olga Vvedenskaya; Yuting Wang; Jacobo Miranda Ackerman; Oskar Knittelfelder; Andrej Shevchenko
- Source:
- Trends in analytical chemistry 2018 pp. -
- ISSN:
- 0165-9936
- Subject:
- biomarkers; blood lipids; diagnostic techniques; epidemiological studies; humans; lipids; monitoring
- Abstract:
- ... Human plasma lipidome has been extensively studied in many pathophysiological contexts with the hope of identifying biomarkers for early diagnostics and monitoring the progression and treatment of a broad spectrum of diseases. However, despite remarkable progress in lipidomics technologies, the concordance of lipidomics measurements between independent laboratories remains limited and not fulfilli ...
- DOI:
- 10.1016/j.trac.2018.10.013
- https://doi.org/10.1016/j.trac.2018.10.013
- Author:
- Nadeem Raza; Beshare Hashemi; Ki-Hyun Kim; Sang-Hun Lee; Akash Deep
- Source:
- Trends in analytical chemistry 2018 v.103 pp. 56-73
- ISSN:
- 0165-9936
- Subject:
- air; aromatic hydrocarbons; humans; risk; soil
- Abstract:
- ... The co-occurrence of various aromatic hydrocarbon compounds (AHs) in all major environmental compartments (e.g., air, water, and soil) and the escalating risks they present to humans and animals highlight the significance of understanding the cycling of these compounds in and across systems. To precisely monitor the behavior of AHs and routes of their exposure, it is critical to obtain accurate me ...
- DOI:
- 10.1016/j.trac.2018.03.012
- https://doi.org/10.1016/j.trac.2018.03.012
- Author:
- Ana Cerúlia Moraes do Carmo; Raphael Sanches Pereira; Tais Gratieri
- Source:
- Trends in analytical chemistry 2017 pp. -
- ISSN:
- 0165-9936
- Subject:
- Food and Drug Administration; World Health Organization; analytical methods; drugs; environmental factors; guidelines; humans; medicine; shelf life; United States
- Abstract:
- ... Stability studies guarantees that quality attributes will be maintained during a period under the influence of a variety of environmental factors, consequently maintaining drug product efficacy and safety. In this context, stability indicating analytical methods (SIAM) appears as a regulatory requirement to detect common observed impurities and those likely to appear during product shelf-life due ...
- DOI:
- 10.1016/j.trac.2017.10.017
- https://doi.org/10.1016/j.trac.2017.10.017
83. Detecting semen stains on fabrics using near infrared hyperspectral images and multivariate models
- Author:
- Carolina S. Silva; Maria Fernanda Pimentel; José Manuel Amigo; Ricardo S. Honorato; Celio Pasquini
- Source:
- Trends in analytical chemistry 2017 pp. -
- ISSN:
- 0165-9936
- Subject:
- absorption; breast milk; children; color; crime; experts; fabrics; forensic sciences; humans; hyperspectral imagery; lubricants; multivariate analysis; principal component analysis; semen
- Abstract:
- ... Identification of semen stains is a critical step in evidence analysis in cases of sexual assaults (rape, child molestation, sexual harassments, etc). Presumptive and confirmatory methodologies that are nondestructive and can be used at crime scenes are extremely needed to help forensic experts to collect useful evidences without compromising the integrity of the samples. In this work, we put forw ...
- DOI:
- 10.1016/j.trac.2017.07.026
- https://doi.org/10.1016/j.trac.2017.07.026
84. Forensic decomposition odour profiling: A review of experimental designs and analytical techniques
- Author:
- Mohammad A. Iqbal; Katie D. Nizio; Maiken Ueland; Shari L. Forbes
- Source:
- Trends in analytical chemistry 2017 v.91 pp. 112-124
- ISSN:
- 0165-9936
- Subject:
- analytical methods; byproducts; experimental design; forensic sciences; humans; instrumentation; odors; people; volatile organic compounds
- Abstract:
- ... The complex process of cadaveric decomposition releases diverse volatile organic compounds (VOCs) as by-products. These VOCs are significant in forensic science as the odour they comprise can be tracked by trained canines when searching for human remains in cases of missing persons, homicide, or mass disaster. Although this is an emerging area of research, numerous studies have been conducted to f ...
- DOI:
- 10.1016/j.trac.2017.04.009
- https://doi.org/10.1016/j.trac.2017.04.009
- Author:
- William J. Nash; Warwick B. Dunn
- Source:
- Trends in analytical chemistry 2018 pp. -
- ISSN:
- 0165-9936
- Subject:
- computational methodology; data collection; humans; liquid chromatography; mass spectrometry; metabolites; metabolomics
- Abstract:
- ... The relatively unbiased study of metabolites in biological systems is called untargeted metabolomics and the application of liquid chromatography-mass spectrometry platforms for data acquisition is now common across the world. When operating in its most unbiased form, this experimental strategy starts from assuming no knowledge of the metabolites to be detected and instead the data acquired is use ...
- DOI:
- 10.1016/j.trac.2018.11.022
- https://doi.org/10.1016/j.trac.2018.11.022
- Author:
- Myrsini Papageorgiou; Dimitra Lambropoulou; Calum Morrison; Ewa Kłodzińska; Jacek Namieśnik; Justyna Płotka-Wasylka
- Source:
- Trends in analytical chemistry 2017 pp. -
- ISSN:
- 0165-9936
- Subject:
- amino acids; analytical methods; biogenic amines; breathing; cheeses; control methods; decarboxylation; fish products; freshness; humans; hypertension; liquids; meat; monitoring; vomiting; wines
- Abstract:
- ... Biogenic amines (BAs) have been reported in a variety of foods, such as fish, meat, cheese, and wines. The formation of BAs in food by the microbial decarboxylation of amino acids can result in human allergic reactions, characterized by difficulty in breathing, rash, vomiting, and hypertension. Control measures to prevent biogenic amine formation in foods and/or reduce their levels should be consi ...
- DOI:
- 10.1016/j.trac.2017.11.001
- https://doi.org/10.1016/j.trac.2017.11.001
- Author:
- Ulrich Höller; Stephan J.L. Bakker; Andre Düsterloh; Balz Frei; Josef Köhrle; Tobias Konz; Georg Lietz; Adrian McCann; Alexander J. Michels; Anne M. Molloy; Hitoshi Murakami; Dietrich Rein; Wim H.M. Saris; Karlheinz Schmidt; Kazutaka Shimbo; Soeren Schumacher; Cees Vermeer; Jim Kaput; Peter Weber; Manfred Eggersdorfer; Serge Rezzi
- Source:
- Trends in analytical chemistry 2018 v.102 pp. 110-122
- ISSN:
- 0165-9936
- Subject:
- detection limit; diagnostic techniques; humans; nutrition research; nutritional status; quality of life
- Abstract:
- ... Micronutrients are essential to health at every life stage and their deficiencies are associated with increased incidence of various pathophysiological states and poor quality of life. Efficient methods are therefore needed to monitor micronutrient status of individuals and to improve evidenced-based recommendations for populations. This review (i) reports current approaches to assess the vitamin ...
- DOI:
- 10.1016/j.trac.2018.02.001
- https://doi.org/10.1016/j.trac.2018.02.001
- Author:
- Gulyaim N. Sagandykova; Paweł P. Pomastowski; Roman Kaliszan; Bogusław Buszewski
- Source:
- Trends in analytical chemistry 2018 v.109 pp. 198-213
- ISSN:
- 0165-9936
- Subject:
- bioactive compounds; bioactive properties; clinical trials; computers; drug design; drugs; genes; humans; mutation; spectroscopy
- Abstract:
- ... Due to the structural diversity of natural compounds in plants kingdom and a wide range of beneficial properties for health, they are attractive to use for various applications. Natural bioactivity means pharmacological effects induced by compounds of interest, which can be a subject of change under different conditions and dependent on individual organism. Development of supercomputers, spectrosc ...
- DOI:
- 10.1016/j.trac.2018.10.012
- https://doi.org/10.1016/j.trac.2018.10.012
- Author:
- Andrew N. Lane; Richard M. Higashi; Teresa W-M. Fan
- Source:
- Trends in analytical chemistry 2018 pp. -
- ISSN:
- 0165-9936
- Subject:
- biochemical pathways; chemoselectivity; derivatization; human diseases; humans; isotope labeling; mass spectrometry; metabolic studies; metabolism; metabolites; metabolomics; neoplasms; nuclear magnetic resonance spectroscopy; stable isotopes; tissues
- Abstract:
- ... There is considerable interest in defining metabolic reprogramming in human diseases, which is recognized as a hallmark of human cancer. Although radiotracers have a long history in specific metabolic studies, stable isotope-enriched precursors coupled with modern high resolution mass spectrometry and NMR spectroscopy have enabled systematic mapping of metabolic networks and fluxes in cells, tissu ...
- DOI:
- 10.1016/j.trac.2018.11.020
- https://doi.org/10.1016/j.trac.2018.11.020
90. Opportunities and challenges of isotopic analysis by laser ablation ICP-MS in biological studies
- Author:
- Lara Lobo; Rosario Pereiro; Beatriz Fernández
- Source:
- Trends in analytical chemistry 2018 v.105 pp. 380-390
- ISSN:
- 0165-9936
- Subject:
- corals; evolution; humans; mass spectrometry; otoliths; paleoecology; provenance; stable isotopes; tissues; vegetables
- Abstract:
- ... Measurement of natural isotopic abundances and isotope ratio variations in hard tissues (such as bone, tooth, coral skeletons and otoliths) either from radiogenic and/or stable isotopes can provide important information about human evolution, palaeoenvironmental reconstructions and provenance. Besides, the addition of stable isotopically-enriched isotopes to vegetables, animals, or even humans, al ...
- DOI:
- 10.1016/j.trac.2018.05.020
- https://doi.org/10.1016/j.trac.2018.05.020
91. Recent developments in analytical quantitation approaches for parabens in human-associated samples
- Author:
- Nadeem Raza; Ki-Hyun Kim; Muhammad Abdullah; Waseem Raza; Richard J.C. Brown
- Source:
- Trends in analytical chemistry 2017 pp. -
- ISSN:
- 0165-9936
- Subject:
- anti-infective agents; breasts; estrogenic properties; exposure pathways; human health; humans; hypersensitivity; metabolites; preservatives; tissues; toxicity
- Abstract:
- ... Parabens are an important class of antimicrobial compounds used as preservatives. Although they are considered to be safe when used within specified concentration limits, concerns about their potential toxicity have been raised due to their presence in cancerous breast tissues and their association with estrogenic activity, various kinds of allergies, and the malfunctioning of reproductive organs. ...
- DOI:
- 10.1016/j.trac.2017.11.009
- https://doi.org/10.1016/j.trac.2017.11.009
- Author:
- Chengmei Jiang; Lingyi Lan; Yao Yao; Fengnian Zhao; Jianfeng Ping
- Source:
- Trends in analytical chemistry 2018 v.102 pp. 236-249
- ISSN:
- 0165-9936
- Subject:
- biosensors; electrochemistry; foods; humans; ochratoxin A; signal transduction; thermal stability
- Abstract:
- ... Ochratoxins are the major components of mycotoxin that exist extensively in plant origin food. In the ochratoxins group, ochratoxin A (OTA) as the most toxic compound, which possesses a high chemical and thermal stability in foodstuff and would do harm to human beings. Hence, it is imperative to develop a simple, rapid, sensitive, robust, and accurate way to determine OTA. Nanomaterial-based biose ...
- DOI:
- 10.1016/j.trac.2018.02.007
- https://doi.org/10.1016/j.trac.2018.02.007
- Author:
- Abdelmonaim Azzouz; Suresh Kumar Kailasa; Sang Soo Lee; Andrés J. Rascón; Evaristo Ballesteros; Ming Zhang; Ki-Hyun Kim
- Source:
- Trends in analytical chemistry 2018 v.108 pp. 347-369
- ISSN:
- 0165-9936
- Subject:
- carbon nanotubes; composite polymers; dendrimers; detection limit; ecosystems; fullerene; graphene; graphene oxide; humans; magnetism; nanocomposites; silicon; solid phase extraction; sorbents; sorption
- Abstract:
- ... Anthropogenic organic contaminants (AOCs) are found to exert significant impacts on the human ecosystem, even at low or trace-level concentrations. To meet the growing demand for their quantitation in diverse environmental media, the use of preconcentration approaches (such as solid phase extraction) has become an essential component to practically upgrade both procedural efficiency and the analyt ...
- DOI:
- 10.1016/j.trac.2018.08.009
- https://doi.org/10.1016/j.trac.2018.08.009
- Author:
- Qingqing Liu; Xiufen Lu; Hanyong Peng; Aleksandra Popowich; Jeffrey Tao; Jagdeesh S. Uppal; Xiaowen Yan; Dana Boe; X. Chris Le
- Source:
- Trends in analytical chemistry 2018 v.104 pp. 171-182
- ISSN:
- 0165-9936
- Subject:
- arsenic; atomic absorption spectrometry; electrospray ionization mass spectrometry; high performance liquid chromatography; humans; metabolites; proteins; risk
- Abstract:
- ... Environmental and health studies of arsenic require the determination of arsenic species of diverse properties and toxicities. This review summarizes recent analytical advances in speciation of phenylarsenicals. Arsenic speciation techniques have taken advantage of high performance liquid chromatography (HPLC) separation with inductively coupled plasma mass spectrometry (ICPMS) and electrospray io ...
- DOI:
- 10.1016/j.trac.2017.10.006
- https://doi.org/10.1016/j.trac.2017.10.006
- Author:
- Julia Bornhorst; Anna P. Kipp; Hajo Haase; Sören Meyer; Tanja Schwerdtle
- Source:
- Trends in analytical chemistry 2018 v.104 pp. 183-190
- ISSN:
- 0165-9936
- Subject:
- Adequate Intakes; biomarkers; copper; health status; homeostasis; humans; manganese; risk factors; selenium; zinc
- Abstract:
- ... Nowadays, the role of trace elements (TE) is of growing interest because dyshomeostasis of selenium (Se), manganese (Mn), zinc (Zn), and copper (Cu) is supposed to be a risk factor for several diseases. Thereby, research focuses on identifying new biomarkers for the TE status to allow for a more reliable description of the individual TE and health status. This review mirrors a lack of well-defined ...
- DOI:
- 10.1016/j.trac.2017.11.007
- https://doi.org/10.1016/j.trac.2017.11.007
- Author:
- Panteleimon G. Takis; Veronica Ghini; Leonardo Tenori; Paola Turano; Claudio Luchinat
- Source:
- Trends in analytical chemistry 2018 pp. -
- ISSN:
- 0165-9936
- Subject:
- automation; cohort studies; humans; inorganic ions; metabolites; metabolome; metabolomics; nuclear magnetic resonance spectroscopy; phenotype; screening; urine
- Abstract:
- ... NMR measures a relatively small portion of the human metabolome, which roughly corresponds to all free small molecules present in concentrations ≥1 μM. However, the method is intrinsically quantitative and highly reproducible and, whenever standardized pre-analytical and analytical procedures are used, it allows for fast fingerprinting and profiling of a variety of biosamples. While developing met ...
- DOI:
- 10.1016/j.trac.2018.10.036
- https://doi.org/10.1016/j.trac.2018.10.036
- Author:
- Sahar Saleem Bhat; Ahsanulhaq Qurashi; Firdous Ahmad Khanday
- Source:
- Trends in analytical chemistry 2017 v.86 pp. 1-13
- ISSN:
- 0165-9936
- Subject:
- DNA; adhesion; angiotensin II; biocompatibility; biosafety; biosensors; bovine serum albumin; crystal structure; diagnostic techniques; drug delivery systems; electrical properties; fluorescence; human serum albumin; humans; infectious diseases; nanomaterials; neoplasms; surface area; synthesis; tissue engineering; zinc oxide
- Abstract:
- ... ZnO nanostructures have attracted great attention from researchers due to their fascinating properties that include high surface-area, better crystallinity, and improved optical and electrical properties. These intriguing properties make them highly desirable for various applications including biosensors, tissue engineering, drug delivery system and cancer diagnostics. Various interesting techniqu ...
- DOI:
- 10.1016/j.trac.2016.10.001
- https://doi.org/10.1016/j.trac.2016.10.001
- Author:
- Mauro Tomassetti; Federico Marini; Remo Bucci; Luigi Campanella
- Source:
- Trends in analytical chemistry 2016 v.79 pp. 371-379
- ISSN:
- 0165-9936
- Subject:
- biosensors; bones; chemometrics; electrochemistry; fossils; humans; surveys; thermogravimetry
- Abstract:
- ... Recently proposed innovative methods for dating archaeological finds reported in the literature are reviewed, together with the researches carried out in this field by our team, using several instrumental techniques (sensor, biosensor, electrochemical, thermal-analytical, and so on). In this framework, particular attention was then focused on examining the main currently adopted methods for bones ...
- DOI:
- 10.1016/j.trac.2015.11.017
- https://doi.org/10.1016/j.trac.2015.11.017
- Author:
- Manjunatha D. Hadagali; Chua L. Suan
- Source:
- Trends in analytical chemistry 2017 v.97 pp. 153-158
- ISSN:
- 0165-9936
- Subject:
- biomarkers; biosensors; cost effectiveness; electronic sensing; explosives; flowers; food contamination; honey bees; humans; nectar; odors; pollen; propolis; researchers; travel
- Abstract:
- ... Humans are being substantially benefitting from the use of honeybees. Honeybees are natural foragers; they travel long distances in search for water, nectar, propolis and pollen. Researchers aim to use these factors for the welfare of mankind, taking advantage of the behavioral characteristics of honeybees to use them as a basis for developing natural biosensors. Through the use of a honeybee sens ...
- DOI:
- 10.1016/j.trac.2017.09.006
- https://doi.org/10.1016/j.trac.2017.09.006
- Author:
- Przemysław Drzewicz; Lucyna Natkaniec-Nowak; Dominika Czapla
- Source:
- Trends in analytical chemistry 2016 v.85 pp. 75-84
- ISSN:
- 0165-9936
- Subject:
- adulterated products; amber; analytical methods; climate change; equipment; evolution; fossils; humans; physicochemical properties; provenance
- Abstract:
- ... Knowledge on fossil resins (including amber and all their various types) has started to develop significantly since the second half of the 20th century mainly due to advancement of analytical methods and equipment. Nowadays, many researchers are focused on investigation of the resins due to not only their decorative appearance and its utilization in jewelry but also unique physicochemical features ...
- DOI:
- 10.1016/j.trac.2016.06.022
- https://doi.org/10.1016/j.trac.2016.06.022