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- Yoon, Soo Hun; Waters, Christopher M.
- Trends in microbiology 2019
- Vibrio cholerae; bacteria; biofilm; cell communication; cholera; cholera toxin; developing countries; diarrhea; digestive system; fimbriae; genetic engineering; humans; mice; models; pathogens; quorum sensing; sanitation; virulence; water pollution
- ... Vibrio cholerae is the bacterial pathogen responsible for the disease cholera, plaguing many developing nations and areas of poor sanitation, and causing about 2.9 million cases and ~95,000 deaths annually. It is transmitted through contaminated water and infects the host using two major virulence factors: toxin-coregulated pilus (TCP) and cholera toxin (CT). TCP is important for colonization of t ...