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You searched for: Journal Trends in microbiology Remove constraint Journal: Trends in microbiology Publication Year 2019 Remove constraint Publication Year: 2019 Subject microorganisms Remove constraint Subject: microorganisms Text Availability Citation in PubAg Remove constraint Text Availability: Citation in PubAg
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1. Drivers, Diversity, and Functions of the Solitary-Bee Microbiota

Author:
Voulgari-Kokota, Anna; McFrederick, Quinn S.; Steffan-Dewenter, Ingolf; Keller, Alexander
Source:
Trends in microbiology 2019 v.27 no.12 pp. 1034-1044
ISSN:
0966-842X
Subject:
biodiversity; host specificity; microorganisms; models; solitary bees
Abstract:
... Accumulating reports of global bee declines have drawn much attention to the bee microbiota and its importance. Most research has focused on social bees, while solitary species have received scant attention despite their enormous biodiversity, ecological importance, and agroeconomic value. We review insights from several recent studies on diversity, function, and drivers of the solitary-bee microb ...
DOI:
10.1016/j.tim.2019.07.011

2. Genetic Circuit-Assisted Smart Microbial Engineering

Author:
Gao, Cong; Xu, Peng; Ye, Chao; Chen, Xiulai; Liu, Liming
Source:
Trends in microbiology 2019 v.27 no.12 pp. 1011-1024
ISSN:
0966-842X
Subject:
DNA replication; biosensors; engineering; genetic engineering; microorganisms
Abstract:
... Rapid advances in DNA synthesis, genetic manipulation, and biosensors have greatly improved the ability to engineer microorganisms with complex functions. By accurately integrating quality biosensors and complex genetic circuits, recently emerged smart microorganisms have enabled exciting opportunities for dissecting complex signaling networks and making responses without artificial intervention. ...
DOI:
10.1016/j.tim.2019.07.005

3. Bystander Selection for Antimicrobial Resistance: Implications for Patient Health

Author:
Morley, Valerie J.; Woods, Robert J.; Read, Andrew F.
Source:
Trends in microbiology 2019 v.27 no.10 pp. 864-877
ISSN:
0966-842X
Subject:
antibiotic resistance; antibiotics; drug therapy; microorganisms; pathogens; patients; risk
Abstract:
... Antimicrobial therapy promotes resistance emergence in target infections and in off-target microbiota. Off-target resistance emergence threatens patient health when off-target populations are a source of future infections, as they are for many important drug-resistant pathogens. However, the health risks of antimicrobial exposure in off-target populations remain largely unquantified, making ration ...
DOI:
10.1016/j.tim.2019.06.004

4. Making the Most of Trait-Based Approaches for Microbial Ecology

Author:
Lajoie, Geneviève; Kembel, Steven W.
Source:
Trends in microbiology 2019 v.27 no.10 pp. 814-823
ISSN:
0966-842X
Subject:
case studies; microbial ecology; microorganisms; phenotype
Abstract:
... There is an increasing interest in applying trait-based approaches to microbial ecology, but the question of how and why to do it is still lagging behind. By anchoring our discussion of these questions in a framework derived from epistemology, we broaden the scope of trait-based approaches to microbial ecology from one oriented mostly around explanation towards one inclusive of the predictive and ...
DOI:
10.1016/j.tim.2019.06.003

5. Contribution of the Mucosal Microbiota to Bovine Respiratory Health

Author:
Zeineldin, Mohamed; Lowe, James; Aldridge, Brian
Source:
Trends in microbiology 2019 v.27 no.9 pp. 753-770
ISSN:
0966-842X
Subject:
bovine respiratory disease; cattle; dysbiosis; ecosystems; environmental factors; homeostasis; microbial ecology; microbiome; microorganisms; pathophysiology; respiratory system
Abstract:
... Recognizing the respiratory tract as a dynamic and complex ecosystem has enhanced our understanding of the pathophysiology of bovine respiratory disease (BRD). There is widespread evidence showing that disease-predisposing factors often disrupt the respiratory microbial ecosystem, provoking atypical colonization patterns and a progressive dysbiosis. The ecological factors that shape the respirator ...
DOI:
10.1016/j.tim.2019.04.005

6. Early-Life Microbiota Perturbations and Behavioral Effects

Author:
Francis, Antonia P.; Dominguez-Bello, Maria Gloria
Source:
Trends in microbiology 2019 v.27 no.7 pp. 567-569
ISSN:
0966-842X
Subject:
cognitive development; maternal behavior; microorganisms; postpartum period; progeny
Abstract:
... The maternal environment, during the prenatal and postnatal periods, is a determinant of offspring development and health. Perturbations during these periods can affect maternal behaviors and maternal–infant bonding, and also impair transmission of maternal microbiota to the offspring. Impaired microbiota has been associated with alterations of offspring cognitive development and behavior. ...
DOI:
10.1016/j.tim.2019.04.004

7. Experimental Evolution as a Tool to Investigate Natural Processes and Molecular Functions

Author:
Remigi, Philippe; Masson-Boivin, Catherine; Rocha, Eduardo P.C.
Source:
Trends in microbiology 2019 v.27 no.7 pp. 623-634
ISSN:
0966-842X
Subject:
antibiotic resistance; directed evolution; evolution; genes; host-pathogen relationships; microorganisms; mutation; natural history; phenotype; phenotypic plasticity
Abstract:
... The experimental evolution (EE) of microbes has allowed evolutionary biologists to examine adaptive processes in real time, generating novel insights into fundamental laws of evolution. Less appreciated is the potential of this approach to advance our understanding of microbial cells and molecular processes as a complement to traditional molecular genetics. The tracking of mutations underlying phe ...
DOI:
10.1016/j.tim.2019.02.003

8. The Macroalgal Holobiont in a Changing Sea

Author:
van der Loos, Luna M.; Eriksson, Britas Klemens; Falcão Salles, Joana
Source:
Trends in microbiology 2019 v.27 no.7 pp. 635-650
ISSN:
0966-842X
Subject:
climate change; coastal ecosystems; ecosystem services; guidelines; hosts; macroalgae; microorganisms
Abstract:
... When studying the effects of climate change on eukaryotic organisms we often oversee a major ecological process: the interaction with microbes. Eukaryotic hosts and microbes form functional units, termed holobionts, where microbes play crucial roles in host functioning. Environmental stress may disturb these complex mutualistic relations. Macroalgae form the foundation of coastal ecosystems worldw ...
DOI:
10.1016/j.tim.2019.03.002

9. Engineering Robust Production Microbes for Large-Scale Cultivation

Author:
Wehrs, Maren; Tanjore, Deepti; Eng, Thomas; Lievense, Jeff; Pray, Todd R.; Mukhopadhyay, Aindrila
Source:
Trends in microbiology 2019 v.27 no.6 pp. 524-537
ISSN:
0966-842X
Subject:
bioreactors; dissolved gases; microorganisms; nutrients; synthetic biology
Abstract:
... Systems biology and synthetic biology are increasingly used to examine and modulate complex biological systems. As such, many issues arising during scaling-up microbial production processes can be addressed using these approaches. We review differences between laboratory-scale cultures and larger-scale processes to provide a perspective on those strain characteristics that are especially important ...
DOI:
10.1016/j.tim.2019.01.006

10. Host, Symbionts, and the Microbiome: The Missing Tripartite Interaction

Author:
Brinker, Pina; Fontaine, Michael C.; Beukeboom, Leo W.; Falcao Salles, Joana
Source:
Trends in microbiology 2019 v.27 no.6 pp. 480-488
ISSN:
0966-842X
Subject:
Wolbachia; endosymbionts; microbiome; microorganisms; phenotype; symbiosis
Abstract:
... Symbiosis between microbial associates and a host is a ubiquitous feature of life on earth, modulating host phenotypes. In addition to endosymbionts, organisms harbour a collection of host-associated microbes, the microbiome that can impact important host traits. In this opinion article we argue that the mutual influences of the microbiome and endosymbionts, as well as their combined influence on ...
DOI:
10.1016/j.tim.2019.02.002

11. The Road Not Taken: The Rumen Microbiome, Functional Groups, and Community States

Author:
Moraïs, Sarah; Mizrahi, Itzhak
Source:
Trends in microbiology 2019 v.27 no.6 pp. 538-549
ISSN:
0966-842X
Subject:
biochemical pathways; ecosystems; microbiome; microorganisms; plant fibers; rumen; symbiosis
Abstract:
... The rumen ecosystem represents a classic example of host–microbiome symbiosis. In this obligatory relationship, the host feeds on plant fibers that can only be degraded through a set of complex metabolic cascades, exclusively encoded in rumen-associated microbes. These various metabolic pathways are distributed across a multitude of microbial populations. Application of basic ecological principles ...
DOI:
10.1016/j.tim.2018.12.011

12. Embracing Environmental Genomics and Machine Learning for Routine Biomonitoring

Author:
Cordier, Tristan; Lanzén, Anders; Apothéloz-Perret-Gentil, Laure; Stoeck, Thorsten; Pawlowski, Jan
Source:
Trends in microbiology 2019 v.27 no.5 pp. 387-397
ISSN:
0966-842X
Subject:
algorithms; artificial intelligence; biotechnology; diagnostic techniques; ecological function; environmental monitoring; metagenomics; microbial ecology; microorganisms
Abstract:
... Genomics is fast becoming a routine tool in medical diagnostics and cutting-edge biotechnologies. Yet, its use for environmental biomonitoring is still considered a futuristic ideal. Until now, environmental genomics was mainly used as a replacement of the burdensome morphological identification, to screen known morphologically distinguishable bioindicator taxa. While prokaryotic and eukaryotic mi ...
DOI:
10.1016/j.tim.2018.10.012

13. An Evolutionary Perspective on Ethylene Sensing in Microorganisms

Author:
Papon, Nicolas; Binder, Brad M.
Source:
Trends in microbiology 2019 v.27 no.3 pp. 193-196
ISSN:
0966-842X
Subject:
ethylene; microorganisms; receptors; signal transduction
Abstract:
... Ethylene is a gas and a plant hormone with wide ranging effects and a well defined signaling pathway. The recent identification of ethylene receptors in various microorganisms provides new insights into the early propagation of the ethylene signaling pathway in the course of evolution. ...
DOI:
10.1016/j.tim.2018.12.002

14. Bacterial Excretion of Cytoplasmic Proteins (ECP): Occurrence, Mechanism, and Function

Author:
Ebner, Patrick; Götz, Friedrich
Source:
Trends in microbiology 2019 v.27 no.2 pp. 176-187
ISSN:
0966-842X
Subject:
cell walls; energy; eukaryotic cells; excretion; immune system; microorganisms; pathogenicity; pathogens; proteins; wastes
Abstract:
... The excretion of cytoplasmic and signal-peptide-less proteins (ECP) by microorganisms and eukaryotes remains a fascinating topic. In principle, it appears to be a waste of energy. However, it turns out that – extracellularly – some cytoplasmic proteins (CPs) exert a completely different function such as contributing to pathogenicity or evasion of the immune system. Such CPs have been referred to a ...
DOI:
10.1016/j.tim.2018.10.006

15. Maternal Vertical Transmission Affecting Early-life Microbiota Development

Author:
Wang, Shaopu; Ryan, C. Anthony; Boyaval, Patrick; Dempsey, Eugene M.; Ross, R. Paul; Stanton, Catherine
Source:
Trends in microbiology 2019
ISSN:
0966-842X
Subject:
adults; human development; human genetics; humans; infancy; microbiome; microorganisms; pregnancy; therapeutics
Abstract:
... The association of the human microbiome with health outcomes has attracted much interest toward its therapeutic manipulation. The likelihood of modulating the human microbiome in early life is high and offers great potential to exert profound effects on human development since the early microbiota shows more flexibility compared to that of adults. The human microbiota, being similar to human genet ...
DOI:
10.1016/j.tim.2019.07.010