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- Waters, W.R.
- United States Department of Agriculture patents 2004 no.US 6,673,566 B1
- nitrites; nitric oxide; disease diagnosis; leukocytes; immune response; bacterial antigens; tuberculosis; bacterial infections; cell-mediated immunity; animal pathogenic bacteria; Mycobacterium; Brucella; animal disease models; USDA; patents; mononuclear leukocytes; United States
- ... Peripheral blood mononuclear cells which have been isolated from an animal that is infected with a microbial pathogen produce nitric oxide in response to stimulation with antigens from that pathogen. Determination of nitric oxide production in cultures of peripheral blood mononuclear cells stimulated with a pathogen's antigens may thus provide an indication of infection of the animal. ...