Jump to Main Content
- Roberts, Lydia M.; Wehrly, Tara D.; Crane, Deborah D.; Bosio, Catharine M.
- Vaccine 2017 v.35 no.19 pp. 2575-2581
- CD4-positive T-lymphocytes; Francisella tularensis; bacteria; breathing; epitopes; immunity; live vaccines; longevity; pathogens; secondary immunization; tularemia; vaccination; virulence; United States
- ... Francisella tularensis subsp. tularensis strain SchuS4 (Ftt) is a highly virulent intracellular bacterium. Inhalation of 10 or fewer organisms results in an acute and potentially lethal disease called pneumonic tularemia. Ftt infections occur naturally in the U.S. and Ftt was developed as a bioweapon. Thus, there is a need for vaccines that protect against this deadly pathogen. Although a live vac ...