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- Goodwin, Tyler J.; Huang, Leaf
- Vaccine 2017 v.35 no.19 pp. 2550-2557
- CD8-positive T-lymphocytes; adjuvants; antigens; calcium phosphates; cecum; chemical elements; colorectal neoplasms; encapsulation; immunotherapy; ligands; lipids; liver; metastasis; models; nanoparticles; nucleotides; peptides; population growth; suppressor cells; vaccines
- ... The lipid calcium phosphate nanoparticle is a versatile platform capable of encapsulating a wide range of phosphorylated molecules from single nucleotides to pDNA. The use of this platform has shown great success as an immunotherapeutic vaccine carrier, capable of delivering co-encapsulated phosphorylated adjuvants and peptides. Three potent vaccine formulations were investigated for anti-cancer e ...
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