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You searched for: Journal Vaccine Remove constraint Journal: Vaccine Publication Year 2014 Remove constraint Publication Year: 2014 Source 2014 v.32 no.41 Remove constraint Source: 2014 v.32 no.41
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1. Concomitant administration of live attenuated Japanese encephalitis chimeric virus vaccine (JE-CV) and measles, mumps, rubella (MMR) vaccine: Randomized study in toddlers in Taiwan

Author:
Huang, Li-Min; Lin, Tzou-Yien; Chiu, Cheng-Hsun; Chiu, Nan-Chang; Chen, Po-Yen; Yeh, Shu-Jen; Boaz, Mark; Hutagalung, Yanee; Bouckenooghe, Alain; Feroldi, Emmanuel
Source:
Vaccine 2014 v.32 no.41 pp. 5363-5369
ISSN:
0264-410X
Subject:
antigens; children; chimerism; immune response; neutralization; neutralizing antibodies; seroconversion; seroprevalence; toddlers; vaccination; vaccines; viral encephalitis; viruses; Taiwan
Abstract:
... Japanese encephalitis (JE) is the most important cause of viral encephalitis in Asia.In this randomized, open-label, multicenter trial in 550 children aged 12 to 18 months in Taiwan, children received one dose of JE-CV and one dose of MMR vaccine. Vaccines were either administered separately 6 weeks apart (Groups ‘JE-CV’ and ‘MMR’, named after which vaccine was given first), or concomitantly (Grou ...
DOI:
10.1016/j.vaccine.2014.02.085

2. Development of serum antibodies during early infancy in rhesus macaques: Implications for humoral immune responses to vaccination at birth

Author:
Shen, Chanjuan; Xu, Huanbin; Liu, David; Veazey, Ronald S.; Wang, Xiaolei
Source:
Vaccine 2014 v.32 no.41 pp. 5337-5342
ISSN:
0264-410X
Subject:
Macaca mulatta; antibodies; antigens; blood serum; dose response; environmental exposure; humans; humoral immunity; immune response; immune system; immunoglobulin A; immunoglobulin G; immunoglobulin M; infancy; neonates; vaccination; vaccines
Abstract:
... A better understanding of immune responses in human infants could lead to more effective immunization and vaccination strategies in early life.Since antibodies are key components of protective vaccine responses, we examined developmental changes in serum levels of immunoglobulins (IgG, IgA, IgM) in infant rhesus macaques from birth through 6 months of age.As in human infants, macaques are born wit ...
DOI:
10.1016/j.vaccine.2014.07.036
PubMed:
25092633
PubMed Central:
PMC4143459

3. Evaluation of nonspreading Rift Valley fever virus as a vaccine vector using influenza virus hemagglutinin as a model antigen

Author:
Oreshkova, N.; Cornelissen, L.A.H.M.; de Haan, C.A.M.; Moormann, R.J.M.; Kortekaas, J.
Source:
Vaccine 2014 v.32 no.41 pp. 5323-5329
ISSN:
0264-410X
Subject:
replicon; virion; antigens; genome; Influenza A virus; vaccination; Rift Valley fever phlebovirus; gene expression; hemagglutinins; mice; viruses; immune response; progeny; vector vaccines
Abstract:
... Virus replicon particles are capable of infection, genome replication and gene expression, but are unable to produce progeny virions, rendering their use inherently safe. By virtue of this unique combination of features, replicon particles hold great promise for vaccine applications. We previously developed replicon particles of Rift Valley fever virus (RVFV) and demonstrated their high efficacy a ...
DOI:
10.1016/j.vaccine.2014.07.051

4. Experiences with provider and parental attitudes and practices regarding the administration of multiple injections during infant vaccination visits: Lessons for vaccine introduction

Author:
Wallace, Aaron S.; Mantel, Carsten; Mayers, Gill; Mansoor, Osman; Gindler, Jacqueline S.; Hyde, Terri B.
Source:
Vaccine 2014 v.32 no.41 pp. 5301-5310
ISSN:
0264-410X
Subject:
adverse effects; attitudes and opinions; childhood; children; developing countries; health care workers; income; pain; parents; psychological stress; systematic review; uncertainty; vaccination; vaccines; United States
Abstract:
... An increasing proportion of childhood immunization visits include administration of multiple injections. Future introduction of vaccines to protect against multiple diseases will further increase the number of injections at routine immunization childhood visits, particularly in developing countries that are still scaling up introductions. Parental and healthcare provider attitudes toward multiple ...
DOI:
10.1016/j.vaccine.2014.07.076

5. Genetic polymorphisms of CXCR5 and CXCL13 are associated with non-responsiveness to the hepatitis B vaccine

Author:
Duan, Zhaojun; Chen, Xiangmei; Liang, Zhenglun; Zeng, Ying; Zhu, Fengcai; Long, Lu; McCrae, Malcolm A.; Zhuang, Hui; Shen, Tao; Lu, Fengmin
Source:
Vaccine 2014 v.32 no.41 pp. 5316-5322
ISSN:
0264-410X
Subject:
CD4-positive T-lymphocytes; CXCR5 receptor; Hepatitis B virus; alleles; chemokine CXCL13; gene expression; haplotypes; hepatitis B; interleukin-21; luciferase; single nucleotide polymorphism; vaccination; vaccines; volunteers
Abstract:
... A cohort based study has been undertaken to investigate the possible association of genetic polymorphisms in genes functionally related to follicular T helper (TfH) cells with non-responsiveness to hepatitis B virus (HBV) vaccination. A total of 24 single nucleotide polymorphisms (SNPs) in 6 TfH related genes (CXCR5, ICOS, CXCL13, IL-21, BCL6 and CD40L) were investigated in 20 non-responders and 4 ...
DOI:
10.1016/j.vaccine.2014.07.064

6. Global vaccine supply. The increasing role of manufacturers from middle income countries

Author:
Francis, Donald P.; Du, Yu-Ping; Precioso, Alexander R.
Source:
Vaccine 2014 v.32 no.41 pp. 5259-5265
ISSN:
0264-410X
Subject:
childhood; developing countries; hepatitis B; income; morbidity; mortality; recombinant vaccines; smallpox
Abstract:
... Hallmarks in the remarkable evolution of vaccines and their application include the eradication of smallpox, the development and delivery of the early childhood vaccines and the emergence of recombinant vaccines initiated by the hepatitis B vaccine. Now we enter a most exciting era as vaccines are increasingly produced and delivered in less developed countries. The results are dramatic decreases i ...
DOI:
10.1016/j.vaccine.2014.07.069

7. Hemozoin as a novel adjuvant for inactivated whole virion influenza vaccine

Author:
Uraki, Ryuta; Das, Subash C.; Hatta, Masato; Kiso, Maki; Iwatsuki-Horimoto, Kiyoko; Ozawa, Makoto; Coban, Cevayir; Ishii, Ken J.; Kawaoka, Yoshihiro
Source:
Vaccine 2014 v.32 no.41 pp. 5295-5300
ISSN:
0264-410X
Subject:
Influenza A virus; adjuvants; animal models; antibodies; humans; immune response; inactivated vaccines; influenza; mice; vaccination; virion; viruses
Abstract:
... Because vaccination is an effective means to protect humans from influenza viruses, extensive efforts have been made to develop not only new vaccines, but also for new adjuvants to enhance the efficacy of existing inactivated vaccines. Here, we examined the adjuvanticity of synthetic hemozoin, a synthetic version of the malarial by-product hemozoin, on the vaccine efficacy of inactivated whole inf ...
DOI:
10.1016/j.vaccine.2014.07.079

8. Influenza vaccine effectiveness against medically-attended influenza illness during the 2012–2013 season in Beijing, China

Author:
Yang, Peng; Thompson, Mark G.; Ma, Chunna; Shi, Weixian; Wu, Shuangsheng; Zhang, Daitao; Wang, Quanyi
Source:
Vaccine 2014 v.32 no.41 pp. 5285-5289
ISSN:
0264-410X
Subject:
Influenza A virus; adults; children; influenza; monitoring; parents; patients; vaccination; vaccines; China
Abstract:
... Influenza vaccine coverage remains low in China, and there is limited information on the preventive value of local vaccination programs.As part of influenza virological surveillance in Beijing, China during the 2012–2013 influenza season, we assessed the vaccine effectiveness (VE) of one or more doses of trivalent inactivated influenza vaccine (IIV3) in preventing medically-attended influenza-like ...
DOI:
10.1016/j.vaccine.2014.07.083

9. Is the adjuvanted influenza vaccine more effective than the trivalent inactivated vaccine in the elderly population? Results of a case–control study

Author:
Spadea, A.; Unim, B.; Colamesta, V.; Meneghini, A.; D’Amici, A.M.; Giudiceandrea, B.; La Torre, G.
Source:
Vaccine 2014 v.32 no.41 pp. 5290-5294
ISSN:
0264-410X
Subject:
case-control studies; databases; educational status; elderly; females; influenza; pneumonia; public health; risk; vaccination; vaccines
Abstract:
... Influenza illness is an important public health problem and annual vaccination is globally recommended for high risk populations.The aim was to evaluate and compare the effectiveness of influenza vaccines in reducing hospitalizations for influenza or pneumonia during two influenza seasons in the elderly.A case–control study was performed, using administrative database of the Local Health Unit Roma ...
DOI:
10.1016/j.vaccine.2014.07.077

10. Neutralizing and cross-neutralizing antibody titres induced by bivalent and quadrivalent human papillomavirus vaccines in the target population of organized vaccination programmes

Author:
Barzon, Luisa; Squarzon, Laura; Masiero, Serena; Pacenti, Monia; Marcati, Giorgia; Mantelli, Barbara; Gabrielli, Liliana; Pascucci, Maria Grazia; Lazzarotto, Tiziana; Caputo, Antonella; Palù, Giorgio
Source:
Vaccine 2014 v.32 no.41 pp. 5357-5362
ISSN:
0264-410X
Subject:
adolescents; antibodies; blood serum; girls; humans; neutralization; neutralization tests; vaccination; vaccines
Abstract:
... Aim of this investigator-initiated study was to evaluate and compare the titres of neutralizing and cross-neutralizing antibodies (NAbs) induced by the bivalent (Cervarix®) and quadrivalent (Gardasil®) HPV vaccines in a cohort of girls aged 11–13 years from organized vaccination programmes. To this aim, HPV16 and HPV18 NAbs were measured by pseudovirion-based neutralization assays in serum collect ...
DOI:
10.1016/j.vaccine.2014.07.014

11. No significant differences in the breadth of the foot-and-mouth disease serotype A vaccine induced antibody responses in cattle, using different adjuvants, mixed antigens and different routes of administration

Author:
Tekleghiorghis, Tesfaalem; Weerdmeester, Klaas; van Hemert-Kluitenberg, Froukje; Moormann, Rob J.M.; Dekker, Aldo
Source:
Vaccine 2014 v.32 no.41 pp. 5330-5336
ISSN:
0264-410X
Subject:
Foot-and-mouth disease virus; adjuvants; aluminum hydroxide; antibodies; antibody formation; cattle; cross reaction; enzyme-linked immunosorbent assay; foot-and-mouth disease; genetic variation; mixing; serotypes; vaccines; viral antigens
Abstract:
... Inactivated whole virus foot-and-mouth disease (FMD) vaccines are used worldwide for protection against FMD, but not all vaccines induce protection against all genetic variants of the same FMD virus serotype. The aim of this study is to investigate whether the “breadth” of the antibody response against different strains of the same FMD virus serotype in cattle could be improved by using a differen ...
DOI:
10.1016/j.vaccine.2014.07.033

12. Safety and preliminary immunogenicity of Cuban pneumococcal conjugate vaccine candidate in healthy children: A randomized phase I clinical trial

Author:
Dotres, Carlos P.; Puga, Rinaldo; Ricardo, Yariset; Broño, Carmen R.; Paredes, Beatriz; Echemendía, Vladimir; Rosell, Sandra; González, Nadezhda; García-Rivera, Dagmar; Valdés, Yury; Goldblatt, David; Vérez-Bencomo, Vicente
Source:
Vaccine 2014 v.32 no.41 pp. 5266-5270
ISSN:
0264-410X
Subject:
children; clinical trials; immune response; immunoglobulin G; infants; serotypes; tetanus; vaccination; vaccines; Cuba
Abstract:
... A new heptavalent conjugate vaccine (PCV7-TT) is under development in Cuba. PCV7-TT contains 2μg of serotypes 1, 5, 14, 18C, 19F, 23F and 4μg of 6B, each one conjugated to tetanus toxoid (TT). This vaccine was designed with the serotypes that cause most invasive pneumococcal diseases (IPD) worldwide. In the present study, we investigated the safety and explored the immunogenicity of PCV7-TT during ...
DOI:
10.1016/j.vaccine.2014.06.094

13. Seroprevalence of IgG antibodies to pertussis toxin in children and adolescents in Estonia

Author:
Jõgi, Piia; Oona, Marje; Toompere, Karolin; Leedo, Sirje; Epstein, Jevgenia; Lutsar, Irja
Source:
Vaccine 2014 v.32 no.41 pp. 5311-5315
ISSN:
0264-410X
Subject:
Bordetella pertussis; adolescents; antibodies; blood serum; children; enzyme-linked immunosorbent assay; hospitals; immunization; immunoglobulin G; pertussis toxin; seroprevalence; vaccines; Estonia
Abstract:
... Despite high immunisation coverage and frequent booster doses, the national notification rates of pertussis in Estonia have been increasing. The peak of 97/100,000 was reached in 2010 which is the highest incidence rate since 1962 (210/100,000).We aimed to measure the prevalence of pertussis toxin (PT) IgG type antibodies in subjects of <18 years and to estimate the pertussis infection activity in ...
DOI:
10.1016/j.vaccine.2014.07.066

14. The effectiveness of influenza vaccination in preventing hospitalizations in children in Hong Kong, 2009–2013

Author:
Cowling, Benjamin J.; Chan, Kwok-Hung; Feng, Shuo; Chan, Eunice L.Y.; Lo, Janice Y.C.; Peiris, J.S. Malik; Chiu, Susan S.
Source:
Vaccine 2014 v.32 no.41 pp. 5278-5284
ISSN:
0264-410X
Subject:
Influenza A virus; children; hospitals; influenza; patients; regression analysis; vaccination; vaccines; China
Abstract:
... Influenza vaccination is widely recommended every year to protect individuals against influenza virus infection and illness. There are few published estimates of influenza vaccine effectiveness against hospitalization in children or from subtropical regions.We conducted a test-negative year-round study between October 2009 and September 2013, recruiting children 6months to 17years of age admitted ...
DOI:
10.1016/j.vaccine.2014.07.084
PubMed:
25092636
PubMed Central:
PMC4165553

15. Therapeutic efficacy of the multi-epitope vaccine CTB-UE against Helicobacter pylori infection in a Mongolian gerbil model and its microRNA-155-associated immuno-protective mechanism

Author:
Lv, Xiaobo; Yang, Jue; Song, Hui; Li, Tong; Guo, Le; Xing, Yingying; Xi, Tao
Source:
Vaccine 2014 v.32 no.41 pp. 5343-5352
ISSN:
0264-410X
Subject:
Helicobacter pylori; Meriones unguiculatus; blood serum; cholera toxin; epitopes; humans; humoral immunity; immune response; immunoglobulin G; infectious diseases; inflammation; interferon-gamma; interleukin-8; lymphocytes; models; spleen; tumor necrosis factor-alpha; urease; vaccination; vaccines
Abstract:
... Vaccination is an effective means of preventing infectious diseases, including those caused by Helicobacter pylori. In this study, we constructed a novel multi-epitope vaccine, CTB-UE, composed of the cholera toxin B subunit and tandem copies of the B and Th cell epitopes from the H. pylori urease A and B subunits. We evaluated the therapeutic efficacy of the multi-epitope vaccine CTB-UE against H ...
DOI:
10.1016/j.vaccine.2014.07.041

16. The vaccine efficacy of recombinant duck enteritis virus expressing secreted E with or without PrM proteins of duck tembusu virus

Author:
Chen, Pucheng; Liu, Jinxiong; Jiang, Yongping; Zhao, Yuhui; Li, Qimeng; Wu, Li; He, Xijun; Chen, Hualan
Source:
Vaccine 2014 v.32 no.41 pp. 5271-5277
ISSN:
0264-410X
Subject:
ducks; vaccines; Tembusu virus; viruses; neutralizing antibodies; glycoproteins; Anatid alphaherpesvirus 1; China
Abstract:
... A newly emerged tembusu virus that causes egg-drop has been affecting ducks in China since 2010. Currently, no vaccine is available for this disease. A live attenuated duck enteritis virus (DEV; a herpesvirus) vaccine has been used routinely to control lethal DEV in ducks since the 1960s. Here, we constructed two recombinant DEVs by transfecting overlapping fosmid DNAs. One virus, rDEV-TE, express ...
DOI:
10.1016/j.vaccine.2014.07.082

17. Varicella hospitalizations in Los Angeles during the varicella vaccination era, 2003–2011: Are they preventable?

Author:
Agopian, Anya; Lopez, Adriana; Wilson, Dulmini; Peralta, Vi; Amin, Alvin Nelson El; Bialek, Stephanie
Source:
Vaccine 2014 v.32 no.41 pp. 5353-5356
ISSN:
0264-410X
Subject:
burden of disease; death; disease severity; people; vaccination; vaccines
Abstract:
... Characteristics of varicella-related hospitalizations in the mature varicella vaccination era, including the proportion vaccinated and the severity of disease, are not well described. We present the vaccination status, severity and reasons for hospitalization of the hospitalized varicella cases reported to the Los Angeles County Health Department from 2003 to 2011, the period which includes the la ...
DOI:
10.1016/j.vaccine.2014.07.035
PubMed:
25087675
PubMed Central:
PMC4855290