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- Shimp, Richard L.; Rowe, Christopher; Reiter, Karine; Chen, Beth; Nguyen, Vu; Aebig, Joan; Rausch, Kelly M.; Kumar, Krishan; Wu, Yimin; Jin, Albert J.; Jones, David S.; Narum, David L.
- Vaccine 2013 v.31 no.28 pp. 2954-2962
- Culicidae; Pseudomonas aeruginosa; amino acid composition; antibodies; clinical trials; cyclic GMP; humans; immune response; infectious diseases; light scattering; malaria; manufacturing; mice; molecular weight; nanoparticles; parasites; pathogenicity; surface proteins; vaccines; United States
- ... Successful efforts to control infectious diseases have often required the use of effective vaccines. The current global strategy for control of malaria, including elimination and eradication will also benefit from the development of an effective vaccine that interrupts malaria transmission. To this end, a vaccine that disrupts malaria transmission within the mosquito host has been investigated for ...
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- Heine, Shannon J.; Diaz-McNair, Jovita; Martinez-Becerra, Francisco J.; Choudhari, Shyamal P.; Clements, John D.; Picking, Wendy L.; Pasetti, Marcela F.
- Vaccine 2013 v.31 no.28 pp. 2919-2929
- Escherichia coli; Shigella; animal models; antigens; blood serum; heat; humans; immune response; immunization; immunoglobulin A; immunoglobulin G; interleukin-10; interleukin-17; interleukin-2; interleukin-5; lungs; mice; morbidity; mortality; mutants; oral administration; pathogens; plasmids; shigellosis; spleen; type III secretion system; vaccines
- ... Shigella spp. are food- and water-borne pathogens that cause shigellosis, a severe diarrheal and dysenteric disease that is associated with a high morbidity and mortality in resource-poor countries. No licensed vaccine is available to prevent shigellosis. We have recently demonstrated that Shigella invasion plasmid antigens (Ipas), IpaB and IpaD, which are components of the bacterial type III secr ...
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