Jump to Main Content
- Brosnan, Robert J.
- Veterinary anaesthesia and analgesia 2011 v.38 no.3 pp. 231-239
- isoflurane, etc ; action potentials; anesthesia; antagonists; aspartic acid; atmosphere; catheters; experimental design; gamma-aminobutyric acid; prospective studies; rats; receptors; tail; Show all 13 Subjects
- ... Objective At the minimum alveolar concentration (MAC), isoflurane potentiates GABAA receptor currents and inhibits NMDA receptor currents, and these actions may be important for producing anesthesia. However, isoflurane modulates GABAA receptors more potently than NMDA receptors. The objective of this study was to test whether isoflurane would function as a more potent NMDA receptor antagonist if ...
- PubMed Central: