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- Bergkvist, G.T.; Argyle, D.J.; Morrison, L.; MacIntyre, N.; Hayes, A.; Yool, D.A.
- Veterinary and comparative oncology 2011 v.9 no.2 pp. 106-117
- biomarkers; biopsy; cats; cell proliferation; correlation; epidermal growth factor receptors; immunohistochemistry; screening
- ... The aims of this study were to establish expression of epidermal growth factor receptor (EGFR) and Ki67 in 67 archived biopsy samples of feline oral squamous cell carcinomas (FOSCCs) and to establish if the expression of either markers was predictive of survival. Samples were immunohistochemically labelled for the two proteins and scored. Statistical analyses of data, including Kaplan-Meier surviv ...
- J. A. Garcia; H. L. Ferreira; F. V. Vieira; R. Gameiro; A. L. Andrade; F. R. Eugênio; E. F. Flores; T. C. Cardoso
- Veterinary and comparative oncology 2017 v.15 no.2 pp. 336-344
- correlation; human cell lines; mitochondrial membrane; membrane potential; cell viability; Respirovirus; humans; necrosis; Canine morbillivirus; dogs; mammary neoplasms (animal); therapeutics; gene expression; cytopathogenicity; neoplasm cells; pets; viral load; death; cell proliferation; apoptosis
- ... Oncolytic virotherapy is a novel strategy for treatment of cancer in humans and companion animals as well. Canine distemper virus (CDV), a paramyxovirus, has proven to be oncolytic through induction of apoptosis in canine‐derived tumour cells, yet the mechanism behind this inhibitory action is poorly understood. In this study, three human mammary tumour cell lines and one canine‐derived adenofibro ...