Journal: Veterinary immunology and immunopathology / Publication Year: 2021 / Source: 2021 v.238

Author:: Zhu, Mengting; Cao, Shaoqi; Zheng, Wei; Zhai, Mengting; Wang, Mingyuan; Blair, Hugh T.; Morris, Stephen Todd; Zhang, Hongmei; Zhao, Zongsheng
Source:: Veterinary immunology and immunopathology 2021 v.238 pp. 110275
ISSN:: 0165-2427
Subject:: Mycoplasma ovipneumoniae; apoptosis; bioinformatics; epithelium; gene expression regulation; genes; immune response; immunopathology; inflammation; luciferase; microRNA; pneumonia; sheep; signal transduction
Abstract:: ... MicroRNAs play a key role in Mannan-binding lectin-mediated resistance to Mycoplasma ovipneumoniae pneumonia, by regulating the translation of mRNAs of target genes, thereby regulating the immune response. Additionally, TRAF6 is a key molecule in Toll-like receptor signal transduction, which mediates inflammation and apoptosis signaling pathways and is widely involved in inflammation and immune re ...
DOI:: 10.1016/j.vetimm.2021.110275
: https://dx.doi.org/10.1016/j.vetimm.2021.110275

Author:: Novoa, María Belén; Sarli, Macarena; Reidel, Ivana Gabriela; Veaute, Carolina; Valentini, Beatriz; Primo, María Evangelina
Source:: Veterinary immunology and immunopathology 2021 v.238 pp. 110285
ISSN:: 0165-2427
Subject:: Escherichia coli; Neospora caninum; adjuvants; cattle production; humoral immunity; immunization; immunoglobulin G; immunopathology; oligodeoxyribonucleotides; recombinant vaccines; tachyzoites
Abstract:: ... Abortions caused by Neospora caninum are a serious problem in cattle production and require effective immunoprophylaxis. The objective of this work was to assess the humoral immune response to four recombinant (r) N. caninum antigens in cattle after immunisation and challenge. MIC1 and MIC3 proteins from the micronemes, SRS2 from the surface of tachyzoites, and GRA7 from the dense granules were ex ...
DOI:: 10.1016/j.vetimm.2021.110285
: https://dx.doi.org/10.1016/j.vetimm.2021.110285

Author:: Schnabel, Christiane L.; Babasyan, Susanna; Freer, Heather; Larson, Elisabeth M.; Wagner, Bettina
Source:: Veterinary immunology and immunopathology 2021 v.238 pp. 110284
ISSN:: 0165-2427
Subject:: biomarkers; flow cytometry; fluorescence; horses; immunopathology; inflammation; monocytes; necrosis; neoplasms
Abstract:: ... Tumor necrosis factor-α (TNF-α) is a pleiotropic cytokine, that is involved in acute inflammation and is employed as a biomarker of inflammatory diseases in several species for which reliable quantification is available. We aimed to develop suitable tools to quantify TNF-α in equine samples. We generated two new mAbs against equine TNF-α (clones 48 and 292), evaluated their specificity for this cy ...
DOI:: 10.1016/j.vetimm.2021.110284
: https://dx.doi.org/10.1016/j.vetimm.2021.110284

Author:: Weerts, Erik A.W.S.; Matthijs, Mieke G.R.; Bonhof, Josette; van Haarlem, Daphne A.; Dwars, R. Marius; Gröne, Andrea; Verheije, M. Hélène; Jansen, Christine A.
Source:: Veterinary immunology and immunopathology 2021 v.238 pp. 110276
ISSN:: 0165-2427
Subject:: Avian metapneumovirus; Avian orthoavulavirus 1; Escherichia coli; Infectious bronchitis virus; air; bacterial antigens; body weight; broiler chickens; euthanasia; gene expression; immune response; immunohistochemistry; immunopathology; interleukin-10; interleukin-17; interleukin-6; lungs; macrophages; models; monocytes; pneumonia; tracheitis
Abstract:: ... Colibacillosis in chickens caused by avian pathogenic Escherichia coli (APEC) is known to be aggravated by preceding infections with infectious bronchitis virus (IBV), Newcastle disease virus (NDV) and avian metapneumovirus (aMPV). The mechanism behind these virus-induced predispositions for secondary bacterial infections is poorly understood. Here we set out to investigate the immunopathogenesis ...
DOI:: 10.1016/j.vetimm.2021.110276
: https://dx.doi.org/10.1016/j.vetimm.2021.110276

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