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- Sparger, Ellen E.; Murphy, Brian G.; Kamal, Farina Mustaffa; Arzi, Boaz; Naydan, Diane; Skouritakis, Chrisoula T.; Cox, Darren P.; Skorupski, Katherine
- Veterinary immunology and immunopathology 2018 v.202 pp. 52-62
- biopsy, etc ; B-lymphocytes; CD4-positive T-lymphocytes; adults; cats; epithelium; head; humans; immunohistochemistry; immunomodulators; immunotherapy; mouth neoplasms; neck; patients; pets; prostaglandin synthase; squamous cell carcinoma; staining; transcription factors; Show all 19 Subjects
- ... Squamous cell carcinoma is the most common oral cancer in the cat and presents as a locally aggressive lesion for which an effective therapeutic protocol remains elusive. Feline oral squamous cell carcinoma (OSCC) shares many clinical characteristics with human head and neck squamous cell carcinoma (HNSCC). Accordingly, present studies were conducted to determine similarities for immune markers sh ...
- White, Amelia G.; Santoro, Domenico; Ahrens, Kim; Marsella, Rosanna
- Veterinary immunology and immunopathology 2018 v.197 pp. 93-101
- biopsy, etc ; Beagle; allergens; analysis of variance; animal disease models; atopic dermatitis; caspases; cyclosporine; dogs; fluorescent antibody technique; immune response; interleukins; messenger RNA; multiple comparison test; pathogenesis; placebos; protein synthesis; reverse transcriptase polymerase chain reaction; transforming growth factor beta; tumor necrosis factor-alpha; Show all 20 Subjects
- ... Ciclosporin (CsA) is a common treatment for canine atopic dermatitis (cAD). cAD is a very common skin disease with a multifactorial pathogenesis due to complex interactions between the host and the environment. The purpose of this study was to describe the physical and immunological effects of CsA in cAD using a canine model of AD. Fourteen beagles were enrolled; seven received CsA orally every 24 ...