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1. Potential evidence for biotype-specific chemokine profile following BVDV infection of bovine macrophages

Author:
Offord, Victoria,   et al.   ; Burr, Stephen; Thomas, Carole; Brownlie, Joe; Coffey, Tracey J.; Werling, Dirk;     Show all 6 Authors
Source:
Veterinary immunology and immunopathology 2012 v.150 no.1-2 pp. 123-127
ISSN:
0165-2427
Subject:
bovine viral diarrhea; cattle; chemokines; gene expression; immune response; macrophages; messenger RNA; monocytes
Abstract:
... Chemokines play a key role in initiating the innate and subsequently adaptive immune response by recruiting immune cells to the site of an infection. Monocytes/macrophages (MØ) are part of the first line of defence against invading pathogens, and have been shown to release a variety of chemokines in response to infection. Here, we reveal the early transcriptional response of MØ to infection with c ...
DOI:
10.1016/j.vetimm.2012.08.009
PubMed:
22985634
PubMed Central:
PMC3778901