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- Werling, D.; Piercy, J.; Coffey, T.J.
- Veterinary immunology and immunopathology 2006 v.112 no.1-2 pp. 2-11
- immunopathology; cattle diseases; cattle; immunomodulators; cell physiology; mycobacterial diseases; receptors; Mycobacterium bovis
- ... Invading pathogens are controlled by the innate and adaptive arms of the immune system. Adaptive immunity, mediated by B and T lymphocytes, recognises pathogens via high affinity receptors. However, the establishment of a primary adaptive immune response is not rapid enough to eradicate invading microorganisms as it involves cell proliferation, gene activation and protein synthesis. More rapid def ...
- Lesellier, S.; Palmer, S.; Dalley, D.J.; Dave, D.; Johnson, L.; Hewinson, R.G.; Chambers, M.A.
- Veterinary immunology and immunopathology 2006 v.112 no.1-2 pp. 24-37
- immunopathology; cattle diseases; immunogenetics; cattle; margin of safety; Mycobacterium bovis BCG; herd health; clinical trials; Meles meles; badgers; BCG vaccine
- ... European badgers (Meles meles) are a wildlife reservoir for Mycobacterium bovis (M. bovis) in Great Britain (GB) and the Republic of Ireland and therefore constitute a potential source of infection for cattle. Reduction of badger densities in the Republic of Ireland has resulted in an associated reduction in the risk of a herd break-down with bovine tuberculosis and a study to determine whether th ...