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- Takamatsu, H.H.; Denyer, M.S.; Stirling, C.; Cox, S.; Aggarwal, N.; Dash, P.; Wileman, T.E.; Barnett, P.V.
- Veterinary immunology and immunopathology 2006 v.112 no.1-2 pp. 49-61
- immunopathology; antigens; T-lymphocytes; swine diseases; vaccines; foot-and-mouth disease; immune response; swine
- ... γδ T cells recognise different types of antigen in alternative ways to αβ T cells, and thus appear to play a complementary role in the immune response. However, unlike αβ T cells, the role or function of γδ T cells is still unclear. As pigs possess a high proportion of circulating γdelta T cells, they are suitable large animal model to study γδ T cell functions. This as yet has not been fully expl ...
- Baigent, S.J.; Smith, L.P.; Nair, V.K.; Currie, R.J.W.
- Veterinary immunology and immunopathology 2006 v.112 no.1-2 pp. 78-86
- immunology; immunopathology; Marek disease; vaccines; disease control; chickens; oncogenic viruses; feathers; vaccine development; vaccination
- ... Marek's disease is an economically important lymphoid neoplasm of chickens, caused by oncogenic strains of Marek's disease herpesvirus. The disease can be successfully controlled by vaccination with attenuated or non-pathogenic MDV strains. However, vaccine failures do occur as field strains continue to evolve towards pathotypes of greater virulence, and this evolution is likely to be driven by th ...