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- Everts, R.E.; Band, M.R.; Liu, Z.L.; Kumar, C.G.; Liu, L.; Loor, J.J.; Oliveira, R.; Lewin, H.A.
- Veterinary immunology and immunopathology 2005 v.105 no.3-4 pp. 235
- microarray technology; complementary DNA; cattle; animal genetics; placenta; spleen; sequence homology; transcription factors; signal transduction; cell cycle; gene expression regulation
- ... The strategy used to create and annotate a 7872 cDNA microarray from cattle placenta and spleen cDNA sequences is described. This microarray contains approximately 6300 unique genes, as determined by BLASTN and TBLASTX similarity search against the human and mouse UniGene and draft human genome sequence databases (build 34). Sequences on the array were annotated with gene ontology (GO) terms, ther ...
- Coussens, P.M.; Pudrith, C.B.; Skovgaard, K.; Ren, X.; Suchyta, S.P.; Stabel, J.R.; Heegaard, P.M.H.
- Veterinary immunology and immunopathology 2005 v.105 no.3-4 pp. 221
- cattle; paratuberculosis; Mycobacterium avium subsp. paratuberculosis; cattle diseases; gene expression; interleukin-5; metalloproteinases; enzyme inhibitors; apoptosis; monocytes; immune response; disease detection; host-pathogen relationships; microarray technology; reverse transcriptase polymerase chain reaction; phenotype
- ... Infection of ruminants with Mycobacterium avium subspecies paratuberculosis (M. paratuberculosis) leads to a chronic and often fatal granulomatous enteritis known as Johne's disease. Most infections with M. paratuberculosis occur during the first 6 months of life, and there is some evidence for transmission in utero. Once established, infections typically exist in a subclinical state for several y ...