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Veterinary immunology and immunopathology
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fibrinogen
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- Author:
- McNeil, Heather J.; Shewen, Patricia E.; Lo, Reggie Y.C.; Conlon, Jennifer A.; Miller, Michael W.
- Source:
- Veterinary immunology and immunopathology 2002 v.90 no.1-2 pp. 107-110
- ISSN:
- 0165-2427
- Subject:
- Mannheimia haemolytica serotype 1; Pasteurella trehalosi; Western blotting; disease control; fibrinogen; pneumonia; serotypes; virulence
- Abstract:
- ... Fibrinogen-binding proteins were found in the culture supernatants of Mannheimia haemolytica serotype 1 (ATCC 43270) and Pasteurella trehalosi serotype 10 (ECO-100). Sheep fibrinogen was biotinylated and shown to bind to proteins in the culture supernatants by modified western blot. Fibrinogen-binding proteins in the culture supernatant may be important virulence factors leading to the characteris ...
- DOI:
- 10.1016/S0165-2427(02)00222-2
- https://doi.org/10.1016/S0165-2427(02)00222-2
- Author:
- Keogh, Brian; Sheahan, Brian J.; Atkins, Gregory J.; Mills, Kingston H.G.
- Source:
- Veterinary immunology and immunopathology 2003 v.94 no.3-4 pp. 185-190
- ISSN:
- 0165-2427
- Subject:
- Semliki Forest virus; apoptosis; arthritis; avirulent strains; blood vessels; blood-brain barrier; fibrinogen; metalloproteinases; mice; models; necrosis; neurons
- Abstract:
- ... Semliki Forest virus (SFV) infection of mice is a useful model of viral neuropathogenesis in animals and avirulent strains such as SFV-A7 induce immune-mediated demyelination and death of neurones by necrosis and apoptosis. Matrix metalloproteinases (MMPs) have been implicated in various diseases including arthritis and cancer in many species. In this report, we show that MMP-2 and MMP-9 expressio ...
- DOI:
- 10.1016/S0165-2427(03)00082-5
- https://doi.org/10.1016/S0165-2427(03)00082-5
- Author:
- De Guise, S.; Erickson, K.; Blanchard, M.; DiMolfetto, L.; Lepper, H.D.; Stott, J.L.; Ferrick, D.A.
- Source:
- Veterinary immunology and immunopathology 2004 v.97 no.3-4 pp. 195-206
- ISSN:
- 0165-2427
- Subject:
- Orcinus orca; T-lymphocytes; Tursiops truncatus; binding sites; fibrinogen; flow cytometry; integrins; monoclonal antibodies; monocytes; neutrophils; phagocytosis; precipitin tests; surface antigens
- Abstract:
- ... The specificity of F21.A, a monoclonal antibody raised against bottlenose dolphin leucocytes, was characterized in killer whale on the basis of immunoprecipitation of a protein of 94 kDa, as well as flow cytometric analysis. While minimally expressed on resting cells, F21.A labeled a homologue to β-2 integrin in 89–97% of PMA-activated neutrophils, 53–66% of activated monocytes, and activated B ce ...
- DOI:
- 10.1016/j.vetimm.2003.09.006
- https://doi.org/10.1016/j.vetimm.2003.09.006
- Author:
- Treiber, Kibby; Carter, Rebecca; Gay, Louisa; Williams, Carey; Geor, Ray
- Source:
- Veterinary immunology and immunopathology 2009 v.129 no.3-4 pp. 216-220
- ISSN:
- 0165-2427
- Subject:
- inflammation; horses; laminitis; biomarkers; tumor necrosis factor-alpha; glutathione; glutathione peroxidase; superoxide dismutase; malondialdehyde; apoptosis; fibrinogen; oxidative stress
- Abstract:
- ... Inflammatory and redox signals could render lamellar tissue susceptible to damage and contribute to higher risk for laminitis in obese or insulin resistant ponies just as these factors contribute to health risks in humans with metabolic syndrome. This study evaluated circulating markers of inflammatory and redox status in ponies that had a history of recurrent bouts of pasture-associated laminitis ...
- DOI:
- 10.1016/j.vetimm.2008.11.004
- https://doi.org/10.1016/j.vetimm.2008.11.004
- Author:
- Mette, Christoffersen; Camilla Dooleweerdt, Baagoe; Stine, Jacobsen; Anders Miki, Bojesen; Morten Roenn, Petersen; Henrik, Lehn-Jensen
- Source:
- Veterinary immunology and immunopathology 2010 v.138 no.1-2 pp. 95-105
- ISSN:
- 0165-2427
- Subject:
- temporal variation; endometritis; anti-inflammatory activity; acute course; biomarkers; fibrinogen; iron; cytokines; female fertility; leukocytes; mares; uterus; immune response; physiological response; horse diseases; bacterial infections; acute phase proteins
- Abstract:
- ... Infectious infertility in the mare is clinically well described, little is however known about the systemic acute phase reaction (APR) and local immunological responses accompanying equine endometritis. The aim of this study was to monitor selected markers of the APR in the systemic circulation and to correlate them to the local innate immune response in the uterus during infectious endometritis. ...
- DOI:
- 10.1016/j.vetimm.2010.07.011
- https://doi.org/10.1016/j.vetimm.2010.07.011
- Author:
- C.J. Piek; B. Brinkhof; E. Teske; J. Rothuizen; A. Dekker; L.C. Penning
- Source:
- Veterinary immunology and immunopathology 2011 v.144 no.3-4 pp. 346-354
- ISSN:
- 0165-2427
- Subject:
- acute phase proteins; coagulation; creatinine; dogs; fibrinogen; gene expression; hemolytic anemia; leukocytes; models; mortality; platelet activation; prognosis; thromboplastin
- Abstract:
- ... A high mortality occurs in dogs with idiopathic immune-mediated haemolytic anaemia (IMHA) during the first 2 weeks after the diagnosis. The aim of this study was to investigate the inflammatory response and coagulation abnormalities in dogs with IMHA in relation to the prognosis and to establish the contribution of whole blood tissue factor (TF) and IL-8 gene expressions. Gene expressions in dogs ...
- DOI:
- 10.1016/j.vetimm.2011.08.010
- PubMed:
- 21899896
- https://doi.org/10.1016/j.vetimm.2011.08.010
- Author:
- M.A. Risalde; V. Molina; P.J. Sánchez-Cordón; M. Pedrera; R. Panadero; F. Romero-Palomo; J.C. Gómez-Villamandos
- Source:
- Veterinary immunology and immunopathology 2011 v.144 no.1-2 pp. 135-143
- ISSN:
- 0165-2427
- Subject:
- secretion; fibrinogen; antibodies; cytotoxicity; cytokines; bovine viral diarrhea; Bovine viral diarrhea virus 1; amyloid; immune response; secondary transmission; calves; pathogens; acute phase proteins
- Abstract:
- ... The aim of this work was to investigate the susceptibility of calves infected with bovine viral diarrhea virus (BVDV) against secondary infections. For this purpose, the profile of cytokines implicated in the immune response of calves experimentally infected with a non-cytopathic strain of BVDV type-1 and challenged with bovine herpesvirus 1.1 (BHV-1.1) was evaluated in comparison with healthy ani ...
- DOI:
- 10.1016/j.vetimm.2011.07.022
- PubMed:
- 21856021
- https://doi.org/10.1016/j.vetimm.2011.07.022
- Author:
- Qiumei You; Chris P. Verschoor; Sameer D. Pant; Joseph Macri; Gordon M. Kirby; Niel A. Karrow
- Source:
- Veterinary immunology and immunopathology 2012 v.148 no.3-4 pp. 243-251
- ISSN:
- 0165-2427
- Subject:
- Holstein; Mycobacterium avium subsp. paratuberculosis; actin; amines; antibodies; binding proteins; biomarkers; chronic diseases; coagulation; complement; computer software; copper; cows; fibrinogen; fluorescence; fluorescent dyes; fluorescent labeling; gel electrophoresis; gels; gene expression regulation; image analysis; isoelectric point; molecular weight; paratuberculosis; peptide mapping; proteome; scanners; screening; thrombin; transferrin; trypsin; typhoons
- Abstract:
- ... Johne's disease (JD) is a widespread and economically important chronic inflammatory disease of the small intestine of ruminants caused by Mycobacterium avium subsp. paratuberculosis (MAP). Although there are several techniques available for diagnosis of JD, their sensitivity is questionable. New proteome profiling methods, such as serum/plasma protein fingerprinting by 2-Dimensional Fluorescence ...
- DOI:
- 10.1016/j.vetimm.2012.05.002
- PubMed:
- 22633222
- https://doi.org/10.1016/j.vetimm.2012.05.002
- Author:
- C.M. Camussone; N. Pujato; M.S. Renna; C.M. Veaute; B. Morein; I.S. Marcipar; L.F. Calvinho
- Source:
- Veterinary immunology and immunopathology 2014 v.162 no.3-4 pp. 96-107
- ISSN:
- 0165-2427
- Subject:
- Staphylococcus aureus; adjuvants; antibodies; binding proteins; bovine mastitis; cytokines; epithelial cells; fibrinogen; fibronectins; heifers; humoral immunity; immune response; mammary glands; milk; models; neutralization; neutrophils; pathogens; phagocytosis; recombinant antigens; vaccines
- Abstract:
- ... Staphylococcus aureus is the most frequently isolated pathogen from bovine intramammary infections worldwide. Commercially available vaccines for mastitis control are composed either of S. aureus lysates or inactivated whole-cells formulated with traditional adjuvants. We recently showed the ability of a S. aureus CP5 lysate vaccine adjuvanted with Iscom Matrix to generate a longer lasting specifi ...
- DOI:
- 10.1016/j.vetimm.2014.10.004
- https://doi.org/10.1016/j.vetimm.2014.10.004
- Author:
- M.K. Nielsen; E.F. Rubinson; T.M. Chambers; D.W. Horohov; B. Wagner; A. Betancourt; S.E. Reedy; S. Jacobsen
- Source:
- Veterinary immunology and immunopathology 2015 v.164 no.3-4 pp. 110-117
- ISSN:
- 0165-2427
- Subject:
- CD4-positive T-lymphocytes; Cyathostominae; West Nile virus; acute phase proteins; amyloid; animal models; anti-inflammatory activity; antibodies; blood serum; eggs; fibrinogen; gender; gene expression; haptoglobins; horses; immune response; inflammation; interferon-gamma; interleukin-10; interleukin-1beta; interleukin-4; iron; ivermectin; keyhole limpet hemocyanin; messenger RNA; mixed breeds; pyrantel; tumor necrosis factors; vaccination; vaccines; yearlings
- Abstract:
- ... Anthelmintics and vaccines are commonly given concurrently in routine equine management, but it is unknown to what extent an interaction between the two exists. Cyathostomins can modulate the local immune response by stimulating a type 2 helper T cell (Th2) response. In addition, anti-inflammatory effects of ivermectin have been found in rodent models. It is unknown whether these anti-inflammatory ...
- DOI:
- 10.1016/j.vetimm.2015.01.009
- https://doi.org/10.1016/j.vetimm.2015.01.009
- Author:
- M.K. Nielsen; A.T. Loynachan; S. Jacobsen; J.C. Stewart; C.R. Reinemeyer; D.W. Horohov
- Source:
- Veterinary immunology and immunopathology 2015 v.168 no.3-4 pp. 203-210
- ISSN:
- 0165-2427
- Subject:
- Cyathostominae; GATA transcription factors; T-lymphocytes; acute phase proteins; amyloid; blood sampling; blood serum; cecum; colon; diarrhea; eosinophils; fenbendazole; fibrinogen; gene expression; grazing; histopathology; horses; interferon-gamma; interleukin-5; iron; juveniles; larvae; larvicides; mortality; moxidectin; necropsy; risk; surface proteins; therapeutics; transforming growth factor beta; tumor necrosis factor-alpha
- Abstract:
- ... Encysted cyathostomin larvae are ubiquitous in grazing horses. Arrested development occurs in this population and can lead to an accumulation of encysted larvae. Large numbers of tissue larvae place the horse at risk for developing larval cyathostominosis. This disease complex is caused by mass emergence of these larvae and is characterized by a generalized acute typhlocolitis and manifests itself ...
- DOI:
- 10.1016/j.vetimm.2015.09.009
- https://doi.org/10.1016/j.vetimm.2015.09.009
- Author:
- Luis G. Fernandes; Gabriela H. Siqueira; Aline R.F. Teixeira; Lucas P. Silva; Jupciana M. Figueredo; Maria R. Cosate; Monica L. Vieira; Ana L.T.O. Nascimento
- Source:
- Veterinary immunology and immunopathology 2016 v.176 pp. 50-57
- ISSN:
- 0165-2427
- Subject:
- Leptospira; adhesins; antigens; bacteria; bacterial adhesion; bacterial colonization; binding proteins; coagulation; complement; death; diagnostic techniques; extracellular matrix; fibrinogen; financial economics; hemorrhage; host-pathogen relationships; humans; immune system; leptospirosis; livestock; milk production; models; nucleotide sequences; pathogenesis; plasmin; plasminogen; proteolysis; receptors; tissues; vaccines; zoonoses
- Abstract:
- ... Leptospirosis is a widespread zoonosis caused by pathogenic Leptospira spp. It is an important infectious disease that affects humans and animals. The disease causes economic losses as it affects livestock, with decreased milk production and death. Our group is investigating the genome sequences of L. interrogans targeting surface-exposed proteins because, due to their location, these proteins are ...
- DOI:
- 10.1016/j.vetimm.2015.12.004
- https://doi.org/10.1016/j.vetimm.2015.12.004
- Author:
- Z.R. Karalyan; Z.R. Ter-Pogossyan; N.Yu. Karalyan; Z.B. Semerjyan; M.R. Tatoyan; S.A. Karapetyan; E.M. Karalova
- Source:
- Veterinary immunology and immunopathology 2017 v.187 pp. 64-68
- ISSN:
- 0165-2427
- Subject:
- African swine fever; African swine fever virus; blood serum; bone marrow; fever; fibrinogen; genotype; granulocyte-macrophage colony-stimulating factor; histology; humans; hypertriglyceridemia; lymph nodes; macrophage colony-stimulating factor; macrophages; spleen; splenomegaly; swine
- Abstract:
- ... Hemophagocytic lymphohistiocytosis (HLH) usually has been defined as the combination of a proliferation of cytologically benign, actively phagocytic macrophages in bone marrow, spleen, lymph nodes, etc. in association with fever, cytopenia, splenomegaly, and hypertriglyceridemia. HLH is often triggered by viral infection. The aim of this study was to ascertain the features of HLH involvement in Af ...
- DOI:
- 10.1016/j.vetimm.2017.03.008
- https://doi.org/10.1016/j.vetimm.2017.03.008
- Author:
- André M. Santana; Daniela G. Silva; Funmilola C. Thomas; Priscila A. Bernardes; Lucas J.L. Pizauro; Clarissa H. Santana; Richard J.S. Burchmore; Peter D. Eckersall; José J. Fagliari
- Source:
- Veterinary immunology and immunopathology 2018 v.203 pp. 30-39
- ISSN:
- 0165-2427
- Subject:
- Salmonella Dublin; acute phase proteins; biomarkers; blood serum; buffaloes; calves; clinical examination; databases; diarrhea; electrophoresis; ferroxidase; fever; fibrinogen; haptoglobins; iron; salmonellosis; signs and symptoms (animals and humans); tandem mass spectrometry; transferrin
- Abstract:
- ... The study aimed to evaluate clinical signs, blood serum acute phase proteins (APP) and iron dynamics during the acute phase response (APR) of Salmonella Dublin experimentally infected Murrah buffalo calves. Six buffalo calves constituted the control group (CNT) and six were orally inoculate with 108 CFU of S. Dublin (INF). Clinical evaluation was performed, rectal swabs to detect S. Dublin strains ...
- DOI:
- 10.1016/j.vetimm.2018.07.014
- https://doi.org/10.1016/j.vetimm.2018.07.014
- Author:
- R. Hoikhman; H. Kudlackova; V. Babak; M. Faldyna; P. Jahn
- Source:
- Veterinary immunology and immunopathology 2018 v.202 pp. 141-146
- ISSN:
- 0165-2427
- Subject:
- antibodies; blood serum; enzyme-linked immunosorbent assay; fibrinogen; horses; humans; immunoglobulin M; rheumatoid arthritis; signs and symptoms (animals and humans); veterinary medicine
- Abstract:
- ... Rheumatoid factor (RF) is used in human and veterinary medicine in the form of IgM RF traditionally to support the diagnosis of rheumatoid arthritis (RA). In the latest diagnostic criteria, presence of anti – citrullinated protein antibodies (ACPA) was added to the grading system for the diagnosis of RA in humans. A change which is not integrated or routinely used in veterinary medicine. The crite ...
- DOI:
- 10.1016/j.vetimm.2018.07.008
- https://doi.org/10.1016/j.vetimm.2018.07.008
- Author:
- Aleksandra Pliszczak-Król; Marianna Gemra; Roland Kozdrowski; Dariusz Zalewski; Alicja Iwaszko
- Source:
- Veterinary immunology and immunopathology 2020 v.230 pp. 110128
- ISSN:
- 0165-2427
- Subject:
- adults; allergens; asthma; chronic diseases; coagulation; fibrin; fibrinogen; fibrinolysis; hay; hemostasis; immunopathology; pathophysiology; prothrombin; straw; thrombin; thromboplastin
- Abstract:
- ... Recurrent Airway Obstruction (RAO), also called severe asthma or heaves, is a chronic disease in adult horses caused by aeroallergens from straw or hay. Disturbances in hemostasis (intensified coagulation and depressed fibrinolysis) are considered one of the prominent reasons of inflammatory process, injury and dysfunction of the lungs. The aim of the study was to evaluate chosen parameters of hem ...
- DOI:
- 10.1016/j.vetimm.2020.110128
- https://doi.org/10.1016/j.vetimm.2020.110128