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- Victoria Offord, et al. Show all 7 Authors
- Veterinary immunology and immunopathology 2016 v.169 pp. 10-14
- Mirounga; endangered species; methicillin-resistant Staphylococcus aureus; marine mammals; population dynamics; Brucella; risk; Toll-like receptor 6; methicillin; bacterial infections; pathogens; Phoca vitulina; disease outbreaks; mortality; antibiotic resistance; innate immunity; Influenza A virus; environmental health; Phocine morbillivirus; vaccine adjuvants; Toll-like receptor 1
- ... Pinnipeds are a diverse clade of semi-aquatic mammals, which act as key indicators of ecosystem health. Their transition from land to marine environments provides a complex microbial milieu, making them vulnerable to both aquatic and terrestrial pathogens, thereby contributing to pinniped population decline. Indeed, viral pathogens such as influenza A virus and phocine distemper virus (PDV) have b ...
- Victoria Offord, et al. Show all 6 Authors
- Veterinary immunology and immunopathology 2012 v.150 no.1-2 pp. 123-127
- bovine viral diarrhea; cattle; chemokines; gene expression; immune response; macrophages; messenger RNA; monocytes
- ... Chemokines play a key role in initiating the innate and subsequently adaptive immune response by recruiting immune cells to the site of an infection. Monocytes/macrophages (MØ) are part of the first line of defence against invading pathogens, and have been shown to release a variety of chemokines in response to infection. Here, we reveal the early transcriptional response of MØ to infection with c ...
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