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- Author:
- Esteve, L.O.; Saz, S.V.; Hosein, S.; Solano-Gallego, L.
- Source:
- Veterinary parasitology 2015 v.209 no.3-4 pp. 157-163
- ISSN:
- 0304-4017
- Subject:
- Leishmania infantum, etc ; Toll-like receptor 2; adaptive immunity; biopsy; cutaneous leishmaniasis; dermatitis; descriptive studies; dogs; granuloma; histopathology; immune response; immunohistochemistry; innate immunity; parasites; pathogenesis; patients; skin lesions; Show all 17 Subjects
- Abstract:
- ... A broad spectrum of clinical manifestations ranging from a chronic subclinical infection to a non-self-limiting illness has been described for canine leishmaniosis (CanL). This clinical variation is determined by a variable immune response, presumably genetically determined, against the infection. Although different types of adaptive immune response in dogs with CanL have been investigated in seve ...
- DOI:
- 10.1016/j.vetpar.2015.03.004
-
https://dx.doi.org/10.1016/j.vetpar.2015.03.004
- Author:
- de Amorim, I.F.G.; Freitas, E.; Alves, C.F.; Tafuri, W.L.; Melo, M.N.; Michalick, M.S.M.; da Costa-Val, A.P.
- Source:
- Veterinary parasitology 2010 v.173 no.1-2 pp. 55-63
- ISSN:
- 0304-4017
- Subject:
- Leishmania donovani, etc ; dogs; dog diseases; visceral leishmaniasis; disease prevention; vaccination; vaccines; humoral immunity; biomarkers; immunoglobulins; validity; strains; xenodiagnosis; immunohistochemistry; polymerase chain reaction; etiology; parasitemia; Brazil; Show all 18 Subjects
- Abstract:
- ... Dogs represent the major reservoir of Leishmaniao chagasi and vaccination against the canine disease is a potential control strategy. However, seroconversion occurs post-vaccine and hence, there is need to discriminate between the former group and naturally infected dogs. The present study represents a comparison of the humoral immunological profiles of both groups using Leishmania soluble antigen ...
- DOI:
- 10.1016/j.vetpar.2010.06.021
-
http://dx.doi.org/10.1016/j.vetpar.2010.06.021
- Author:
- Yisaschar-Mekuzas, Yael; Jaffe, Charles L.; Pastor, Josep; Cardoso, Luís; Baneth, Gad
- Source:
- Veterinary parasitology 2013 v.191 no.3-4 pp. 367-373
- ISSN:
- 0304-4017
- Subject:
- Leishmania infantum, etc ; Babesia canis; Babesia gibsoni; Dermacentor reticulatus; Ehrlichia canis; Hepatozoon canis; Theileria; blood; blood sampling; detection limit; dogs; hybridization; pathogens; polymerase chain reaction; rural areas; taxonomy; ticks; Israel; Middle East; Show all 19 Subjects
- Abstract:
- ... Canine infection by vector-borne hemoparasites is frequent in tropical and sub-tropical areas where exposure to hematophageous ectoparasites is intensive. A reverse line blot (RLB) assay was designed to improve the simultaneous detection of all named canine piroplasm species combined with other vector-borne pathogens of dogs including Ehrlichia canis, Hepatozoon canis and Leishmania infantum commo ...
- DOI:
- 10.1016/j.vetpar.2012.09.002
- PubMed:
- 23017370
-
https://dx.doi.org/10.1016/j.vetpar.2012.09.002
- Author:
- Lopes, Valeriana Valadares; Belo, Vinícius Silva; Pereira, Diego Andrade; Coelho, Marina Bellico; Pena, Heber Paulino; Alves, Natália Ribeiro; de Carvalho Júnior, Clovis Gomes; Werneck, Guilherme Loureiro; Paz, Gustavo Fontes; de Azambuja Ribeiro, Rosy Iara Maciel; da Silva, Eduardo Sergio; Teixeira-Neto, Rafael Gonçalves
- Source:
- Veterinary parasitology 2018 v.261 pp. 96-103
- ISSN:
- 0304-4017
- Subject:
- Leishmania infantum, etc ; Anaplasma platys; Babesia canis subsp. vogeli; Ehrlichia canis; Hepatozoon canis; biomarkers; blood serum; death; disease course; dog diseases; dogs; histopathology; hyperkeratosis; immunoglobulin G; mixed infection; monitoring; mucosa; probability; regression analysis; signs and symptoms (animals and humans); urea; visceral leishmaniasis; weight loss; Show all 23 Subjects
- Abstract:
- ... Canine visceral leishmaniosis (CVL), a parasitic disease caused by Leishmania infantum, may evolve to a chronic condition and lead to death. Evaluation of infected dogs is important to establish the clinical and laboratory parameters involved in the evolution of the disease. The objectives of the present study were to discriminate a canine population (n = 52) into sub-clinical and clinically affec ...
- DOI:
- 10.1016/j.vetpar.2018.08.016
-
https://dx.doi.org/10.1016/j.vetpar.2018.08.016
- Author:
- Oliveira, Trícia M.F.S.; Mineo, Tiago W.P.; Bason, Melina; Day, Michael J.; Machado, Rosangela Z.
- Source:
- Veterinary parasitology 2009 v.162 no.1-2 pp. 16-22
- ISSN:
- 0304-4017
- Subject:
- Leishmania donovani, etc ; disease reservoirs; immunoglobulin G; zoonoses; seroprevalence; dog diseases; dogs; emerging diseases; animal pathogens; visceral leishmaniasis; enzyme-linked immunosorbent assay; monoclonal antibodies; seroconversion; immune response; vaccination; signs and symptoms (animals and humans); Brazil; Show all 17 Subjects
- Abstract:
- ... Leishmaniosis is a zoonotic disease that is caused by Leishmania chagasi and transmitted by sandflies. In Brazil, canine visceral leishmaniosis (CVL) is an emerging disease in urban areas and dogs are the main reservoir host. The aim of the present study was to analyze IgG seroconversion of dogs to L. chagasi and to determine whether there was dominance of any particular IgG subclasses in this imm ...
- DOI:
- 10.1016/j.vetpar.2009.02.018
- PubMed:
- 19345019
-
http://dx.doi.org/10.1016/j.vetpar.2009.02.018
- Author:
- Pereira, Bernardo Acácio Santini; Alves, Carlos Roberto
- Source:
- Veterinary parasitology 2008 v.158 no.4 pp. 239-255
- ISSN:
- 0304-4017
- Subject:
- Leishmania amazonensis, etc ; mice; leishmaniasis; animal models; inoculum; immune response; zoonoses; Show all 7 Subjects
- Abstract:
- ... The murine models of Leishmania infection are well-studied and suitable models for studying this disease, which, despite its incidence of nearly 2 million new cases worldwide per year and its prevalence of 12 million cases, has been a somewhat neglected disease. Data obtained using such models are important for a better understanding of the disease in humans due to similarities in physiology and t ...
- DOI:
- 10.1016/j.vetpar.2008.09.015
- PubMed:
- 18922635
-
http://dx.doi.org/10.1016/j.vetpar.2008.09.015
- Author:
- Shahbazi, Mehdi; Zahedifard, Farnaz; Saljoughian, Noushin; Doroud, Delaram; Jamshidi, Shahram; Mahdavi, Niousha; Shirian, Sadegh; Daneshbod, Yahya; Hamid Zarkesh-Esfahani, Sayyed; Papadopoulou, Barbara; Rafati, Sima
- Source:
- Veterinary parasitology 2015 v.212 no.3-4 pp. 130-139
- ISSN:
- 0304-4017
- Subject:
- Leishmania donovani; Leishmania infantum, etc ; DNA; antigens; cysteine proteinases; delayed hypersensitivity; dog diseases; dogs; electroporation; humans; immune response; immunoglobulin G; interferon-gamma; interleukin-10; nanoparticles; parasites; recombinant vaccines; tumor necrosis factor-alpha; vaccination; vaccine development; visceral leishmaniasis; Show all 21 Subjects
- Abstract:
- ... Visceral leishmaniasis (VL) is a fatal disease caused by the intracellular protozoan parasite Leishmania infantum. Dogs are the primary reservoirs of this parasite, and vaccination of dogs could be an effective method to reduce its transfer to humans. In order to develop a vaccine against VL (apart from the choice of immunogenic candidate antigens), it is necessary to use an appropriate delivery s ...
- DOI:
- 10.1016/j.vetpar.2015.07.005
-
https://dx.doi.org/10.1016/j.vetpar.2015.07.005
- Author:
- de Almeida Leal, Gleisiane Gomes; Roatt, Bruno Mendes; de Oliveira Aguiar-Soares, Rodrigo Dian; Carneiro, Cláudia Martins; Giunchetti, Rodolfo Cordeiro; Teixeira-Carvalho, Andréa; Martins-Filho, Olindo Assis; Francisco, Amanda Fortes; Cardoso, Jamille Mirelle; Mathias, Fernando Augusto Siqueira; Correa-Oliveira, Rodrigo; Carneiro, Mariângela; Coura-Vital, Wendel; Reis, Alexandre Barbosa
- Source:
- Veterinary parasitology 2014 v.205 no.3-4 pp. 472-482
- ISSN:
- 0304-4017
- Subject:
- Leishmania infantum, etc ; B-lymphocytes; T-lymphocytes; anemia; antigens; disease course; dog diseases; dogs; eosinophils; flow cytometry; hematologic tests; immune response; interferons; interleukins; monocytes; neutrophils; parasites; polymerase chain reaction; public health; seroprevalence; visceral leishmaniasis; Brazil; Show all 22 Subjects
- Abstract:
- ... Visceral leishmaniasis has a great impact on public health, and dogs are considered the main domestic reservoir of Leishmania infantum, the causal parasite. In this study, 159 animals naturally infected by L. infantum from an endemic area of Brazil were evaluated through an analysis of cellular responses, using flow cytometry, and of the hematological parameters. The results confirmed that disease ...
- DOI:
- 10.1016/j.vetpar.2014.08.022
-
https://dx.doi.org/10.1016/j.vetpar.2014.08.022
- Author:
- Lima, B.S.S.; Fialho, L.C.; Pires, S.F.; Tafuri, W.L.; Andrade, H.M.
- Source:
- Veterinary parasitology 2016 v.223 pp. 115-119
- ISSN:
- 0304-4017
- Subject:
- Leishmania amazonensis; Leishmania braziliensis; Leishmania infantum, etc ; Western blotting; antibodies; antibody detection; antigen detection; bioinformatics; blood serum; diagnostic techniques; dogs; hosts; mass spectrometry; protein secretion; proteins; pyruvate dehydrogenase (lipoamide); screening; Show all 17 Subjects
- Abstract:
- ... Leishmania spp have a wide range of hosts, and each host can harbor several Leishmania species. Dogs, for example, are frequently infected by Leishmania infantum, where they constitute its main reservoir, but they also serve as hosts for L. braziliensis and L. amazonensis. Serological tests for antibody detection are valuable tools for diagnosis of L. infantum infection due to the high levels of a ...
- DOI:
- 10.1016/j.vetpar.2016.04.019
-
https://dx.doi.org/10.1016/j.vetpar.2016.04.019
- Author:
- Montoya, A.; García, M.; Gálvez, R.; Checa, R.; Marino, V.; Sarquis, J.; Barrera, J.P.; Rupérez, C.; Caballero, L.; Chicharro, C.; Cruz, I.; Miró, G.
- Source:
- Veterinary parasitology 2018 v.251 pp. 125-130
- ISSN:
- 0304-4017
- Subject:
- Leishmania infantum, etc ; Cestoda; Feline immunodeficiency virus; Feline leukemia virus; Giardia lamblia; Otodectes cynotis; Siphonaptera; Toxocara cati; Toxoplasma gondii; animal welfare; antibodies; blood sampling; case-control studies; cats; control methods; definitive hosts; disease transmission; endoparasites; feces; oocysts; polymerase chain reaction; predation; public health; seroprevalence; ticks; urban areas; wild animals; zoonoses; Spain; Show all 29 Subjects
- Abstract:
- ... Cats are definitive hosts and reservoirs for several parasites, some of which are responsible for serious zoonotic diseases. We conducted a case-control study of data from a trap-neuter-return (TNR) programme (years 2014–2017) designed to examine the prevalence of zoonotic parasites in free-roaming cats living in urban areas of central Spain. In the animal population tested (n = 263), we detected ...
- DOI:
- 10.1016/j.vetpar.2018.01.009
-
https://dx.doi.org/10.1016/j.vetpar.2018.01.009
- Author:
- Martín-Sánchez, J.; Acedo, C.; Munoz-Perez, M.; Pesson, B.; Marchal, O.; Morillas-Márquez, F.
- Source:
- Veterinary parasitology 2007 v.145 no.3-4 pp. 267-273
- ISSN:
- 0304-4017
- Subject:
- Leishmania infantum, etc ; epidemiological studies; disease detection; seroprevalence; cats; immunosuppression; antibody detection; leishmaniasis; Feline leukemia virus; mixed infection; parasitemia; Feline immunodeficiency virus; Spain; Show all 13 Subjects
- DOI:
- 10.1016/j.vetpar.2006.11.005
-
http://dx.doi.org/10.1016/j.vetpar.2006.11.005
- Author:
- Maroli, M.; Pennisi, M.G.; Di Muccio, T.; Khoury, C.; Gradoni, L.; Gramiccia, M.
- Source:
- Veterinary parasitology 2007 v.145 no.3-4 pp. 357-360
- ISSN:
- 0304-4017
- Subject:
- Leishmania infantum, etc ; cats; leishmaniasis; xenodiagnosis; disease transmission; infection; Phlebotomus perniciosus; insect vectors; pathogen identification; genotype; restriction fragment length polymorphism; Show all 11 Subjects
- DOI:
- 10.1016/j.vetpar.2006.11.009
-
http://dx.doi.org/10.1016/j.vetpar.2006.11.009
- Author:
- Michalsky, E.M.; Rocha, M.F.; Lima, A.C.V.M. da R.; França-Silva, J.C.; Pires, M.Q.; Oliveira, F.S.; Pacheco, R.S.; Santos, S.L. dos; Barata, R.A.; Romanha, A.J.
- Source:
- Veterinary parasitology 2007 v.147 no.1-2 pp. 67-76
- ISSN:
- 0304-4017
- Subject:
- Leishmania infantum, etc ; dogs; visceral leishmaniasis; seroprevalence; pathogen identification; pathogenicity; signs and symptoms (animals and humans); insect vectors; Lutzomyia longipalpis; xenodiagnosis; disease detection; polymerase chain reaction; epidemiological studies; Brazil; Show all 14 Subjects
- DOI:
- 10.1016/j.vetpar.2007.03.004
-
http://dx.doi.org/10.1016/j.vetpar.2007.03.004
- Author:
- Moreira, Pamela Rodrigues Reina; de Barros Bandarra, Marcio; Magalhães, Geórgia Modé; Munari, Danísio Prado; Machado, Gisele Fabrino; Prandini, Marcelo Martinasso; Alessi, Antonio Carlos; de Oliveira Vasconcelos, Rosemeri
- Source:
- Veterinary parasitology 2013 v.192 no.1-3 pp. 149-157
- ISSN:
- 0304-4017
- Subject:
- Leishmania, etc ; T-lymphocytes; apoptosis; atrophy; clinical examination; dermis; dogs; ears; immune evasion; immunohistochemistry; inflammation; insect vectors; lymph nodes; lymphadenitis; macrophages; parasite load; parasites; skin lesions; visceral leishmaniasis; Brazil; Show all 20 Subjects
- Abstract:
- ... In canine visceral leishmaniasis (CVL), the abnormalities most commonly observed in clinical examination on the animals are lymphadenomegaly and skin lesions. Dogs are the main domestic reservoir for the protozoon Leishmania (L.) chagasi and the skin is the main site of contamination by the vector insect. Some protozoa use apoptosis as an immunological escape mechanism. The aim of this study was t ...
- DOI:
- 10.1016/j.vetpar.2012.09.029
- PubMed:
- 23084537
-
https://dx.doi.org/10.1016/j.vetpar.2012.09.029
- Author:
- Rosypal, A.C.; Hall, J.E.; Bakunova, S.; Patrick, D.A.; Bakunov, S.; Stephens, C.E.; Kumar, A.; Boykin, D.W.; Tidwell, R.R.
- Source:
- Veterinary parasitology 2007 v.145 no.3-4 pp. 207-216
- ISSN:
- 0304-4017
- Subject:
- Leishmania infantum, etc ; leishmaniasis; antiprotozoal agents; aromatic compounds; amidines; cations; medicinal properties; promastigotes; dogs; in vitro studies; Show all 10 Subjects
- DOI:
- 10.1016/j.vetpar.2007.01.005
-
http://dx.doi.org/10.1016/j.vetpar.2007.01.005
- Author:
- Rondon, Fernanda C.M.; Bevilaqua, Claudia M.L.; Accioly, Marina P.; Morais, Selene M.; Andrade-Junior, Heitor F.; Machado, Lyeghyna K.A.; Cardoso, Roselaine P.A.; Almeida, Camila A.; Queiroz-Junior, Eudson M.; Rodrigues, Ana Caroline M.
- Source:
- Veterinary parasitology 2011 v.178 no.3-4 pp. 235-240
- ISSN:
- 0304-4017
- Subject:
- Leishmania infantum, etc ; Aloe vera; Coriandrum sativum; Lutzomyia longipalpis; Ricinus communis; acetates; amastigotes; amphotericin B; bromides; chloroform; colorimetry; control methods; cytotoxicity; dogs; enzyme-linked immunosorbent assay; humans; in vitro studies; in vivo studies; methanol; mice; parasites; promastigotes; tetrazolium dyes; urban areas; viability; visceral leishmaniasis; zoonoses; Brazil; Show all 28 Subjects
- Abstract:
- ... In South America, visceral leishmaniasis is a zoonosis caused by the protozoan species Leishmania infantum (syn. L. chagasi) and is primarily transmitted through the bite of the female Lutzomyia longipalpis. Its main reservoir in urban areas is the dog. The application of control measures recommended by health agencies have not achieved significant results in reducing the incidence of human cases, ...
- DOI:
- 10.1016/j.vetpar.2011.01.007
- PubMed:
- 21320755
-
http://dx.doi.org/10.1016/j.vetpar.2011.01.007
- Author:
- Tunon, Gabriel Isaias Lee; de Moura, Tatiana Rodrigues; de Jesus, Amelia Ribeiro; de Almeida, Roque Pacheco
- Source:
- Veterinary parasitology 2015 v.212 no.3-4 pp. 417-421
- ISSN:
- 0304-4017
- Subject:
- Leishmania infantum, etc ; Cerdocyon thous; amastigotes; blood; blood sampling; disease control; dogs; foxes; macrophages; promastigotes; visceral leishmaniasis; zoonoses; zoos; Brazil; Show all 14 Subjects
- Abstract:
- ... Wild canids are natural reservoirs of visceral leishmaniais (VL). In Brazil, only the crab-eating fox (Cerdocyon thous) is a natural reservoir of this zoonotic disease, but there is still a lack of understanding regarding the sylvatic transmission of the Leishmania infantum infection. This is the first study on the isolation, cultivation and infection with L. infantum in the peripheral blood monon ...
- DOI:
- 10.1016/j.vetpar.2015.06.027
-
https://dx.doi.org/10.1016/j.vetpar.2015.06.027
- Author:
- Aït-Oudhia, K.; Gazanion, E.; Sereno, D.; Oury, B.; Dedet, J.P.; Pratlong, F.; Lachaud, L.
- Source:
- Veterinary parasitology 2012 v.187 no.3-4 pp. 386-393
- ISSN:
- 0304-4017
- Subject:
- Leishmania infantum, etc ; amphotericin B; antimony; dogs; parasites; urban areas; Show all 6 Subjects
- Abstract:
- ... The aim of this study was to evaluate the susceptibility to anti-leishmanial agents of 24 strains isolated from dogs living in the urban area of Alger lacking drug selection pressure. Two different Leishmania infantum zymodemes, MON-1 and MON-281, were identified in these dogs. The in vitro susceptibility to the main forms of antimonial and amphotericin were assessed on promastigote and amastigote ...
- DOI:
- 10.1016/j.vetpar.2012.01.034
- PubMed:
- 22349936
-
http://dx.doi.org/10.1016/j.vetpar.2012.01.034
- Author:
- Patel, Jay M.; Rosypal, Alexa C.; Zimmerman, Kurt L.; Monroe, William E.; Sriranganathan, Nammalwar; Zajac, Anne M.; Yabsley, Michael J.; Lindsay, David S.
- Source:
- Veterinary parasitology 2012 v.187 no.3-4 pp. 394-398
- ISSN:
- 0304-4017
- Subject:
- Leishmania, etc ; Cocker Spaniel; DNA; Procyon lotor; Trypanosoma cruzi; antibodies; blood; dogs; epimastigotes; females; genotype; genotyping; heart; immunoaffinity chromatography; mice; parasites; pathogenicity; promastigotes; Virginia; Show all 19 Subjects
- Abstract:
- ... Trypanosoma cruzi was demonstrated in blood smears and heart tissue from a 5-year old, female, English Cocker Spaniel that had never been outside of the state of Virginia, USA. Plasma from the dog was positive in a commercially available immunochromatographic dipstick assay for T. cruzi and negative in an immunochromatographic dipstick assay for visceral Leishmania spp. The plasma from the dog had ...
- DOI:
- 10.1016/j.vetpar.2012.01.031
- PubMed:
- 22341614
-
http://dx.doi.org/10.1016/j.vetpar.2012.01.031
- Author:
- Santos, Roseclea Chagas dos; Pinho, Flaviane Alves de; Passos, Gabriela Porfírio; Larangeira, Daniela Farias; Barrouin-Melo, Stella Maria
- Source:
- Veterinary parasitology 2018 v.257 pp. 10-14
- ISSN:
- 0304-4017
- Subject:
- Leishmania infantum, etc ; blood; chickens; culture media; dog diseases; dogs; horses; microscopy; oxen; parasite load; parasites; quantitative polymerase chain reaction; rabbits; sheep; spleen; visceral leishmaniasis; Show all 16 Subjects
- Abstract:
- ... The most commonly used culture medium for the in vitro isolation of Leishmania spp. from canine biological samples is biphasic Novy-MacNeal-Nicolle (NNN) medium, whose solid phase is prepared using rabbit blood. Leishmania infantum parasites from natural infections are highly sensitive and demanding for growth in axenic conditions when firstly obtained from the dog’s body. The objective of this st ...
- DOI:
- 10.1016/j.vetpar.2018.05.010
-
https://dx.doi.org/10.1016/j.vetpar.2018.05.010