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- Pushko, Peter; Tretyakova, Irina; Hidajat, Rachmat; Zsak, Aniko; Tumpey, Terrence M.; Kapczynski, Darrell R.; Chrzastek, Klaudia
- Virology 2017 v.501 pp. 176-182
- Baculoviridae; Influenza A virus; antigens; antimicrobial properties; avian influenza; chickens; enzyme activity; hemagglutination; hemagglutinins; models; pathogenicity; sialidase; vaccines; virus-like particles; viruses; wild birds
- ... Avian influenza (AI) viruses circulating in wild birds pose a serious threat to public health. Human and veterinary vaccines against AI subtypes are needed. Here we prepared triple-subtype VLPs that co-localized H5, H7 and H9 antigens derived from H5N1, H7N3 and H9N2 viruses. VLPs also contained influenza N1 neuraminidase and retroviral gag protein. The 5/H7/H9/N1/gag VLPs were prepared using bacu ...
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