Jump to Main Content
- Wu, Shuo, et al. Show all 8 Authors
- Virology journal 2017 v.14 no.1 pp. 2
- Berberis vulgaris; Enterovirus A; RNA; Western blotting; antiviral properties; autophagy; berberine; cytopathogenicity; fluorescent antibody technique; mitogen-activated protein kinase; phosphorylation; protein synthesis; quantitative polymerase chain reaction; reverse transcriptase polymerase chain reaction; signal transduction
- ... BACKGROUND: The MEK-ERK signaling pathway and autophagy play an important role for enterovirus71(EV71) replication. Inhibition of MEK-ERK signaling pathway and autophagy is shown to impair EV71 replication. Berberine (BBR), an isoquinoline alkaloid isolated from Berberis vulgaris L., has been reported to have ability to regulate this signaling pathway and autophagy. Herein, we want to determine wh ...
- PubMed Central: