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- Lundstrom, Kenneth
- Virus research 2016 v.216 pp. 16-25
- Alphavirus; animal models; brain; electrophysiology; gene therapy; genes; genetic vectors; immunization; ion channels; neurons; neurophysiology; rodents
- ... Alphavirus-based vectors have been engineered for in vitro and in vivo expression of heterelogous genes. The rapid and easy generation of replication-deficient recombinant particles and the broad range of host cell infection have made alphaviruses attractive vehicles for applications in neuroscience and gene therapy. Efficient delivery to primary neurons and hippocampal slices has allowed localiza ...