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You searched for: Journal Zeitschrift für Naturforschung Remove constraint Journal: Zeitschrift für Naturforschung Publication Year 2014 Remove constraint Publication Year: 2014 Source 2014 v.64 no.5-6 Remove constraint Source: 2014 v.64 no.5-6
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1. Alkaloids from Sternbergia colchiciflora

Author:
Berkov, Strahil; Bastida, Jaume; Tsvetkova, Reneta; Viladomat, Francesc; Codina, Carles
Source:
Zeitschrift für Naturforschung 2014 v.64 no.5-6 pp. 311-316
ISSN:
1865-7125
Subject:
Sternbergia; bioactive properties; bulbs; dormancy; fructification; gas chromatography-mass spectrometry; leaf development; leaves; lycorine; nuclear magnetic resonance spectroscopy; phenology; plant extracts; plant organs
Abstract:
... Twenty-one alkaloids and related compounds were found in Sternbergia colchiciflora (Amaryllidaceae), a hitherto not studied plant species. Twenty of them were detected by GC-MS in the crude extracts of this plant species. Ten alkaloids were isolated and their structures confirmed by NMR, MS and CD measurements. Many of the compounds found in this species, such as lycorine, tazettine, haemanthidine ...
DOI:
10.1515/znc-2009-5-601

2. Alkylation of Adenosine Deaminase and Thioredoxin by Acrylamide in Human Cell Cultures

Author:
Schwend, Thomas; Möller, Maren; Schabacker, Jens; Ruppert, Thomas; Wink, Michael
Source:
Zeitschrift für Naturforschung 2014 v.64 no.5-6 pp. 447-453
ISSN:
0939-5075
Subject:
acrylamides; adenosine deaminase; alkylation; cell culture; cytotoxicity; humans; neurotoxicity; proteins; thioredoxins
Abstract:
... Acrylamide is an α,β-unsaturated vinyl monomer that causes cytotoxicity due to its alkylating properties. In recent years several proteins have been identified that are alkylated by acrylamide in vivo. This finding might explain the neurotoxic effects of acrylamide in humans. However, the list of potential acrylamide target proteins is far from being complete. In particular, the proteins that medi ...
DOI:
10.1515/znc-2009-5-624

3. A New Tetrahydrofuran Derivative from the Endophytic Fungus Chaetomium sp. Isolated from Otanthus maritimus

Author:
Aly, Amal H.; Debbab, Abdessamad; Edrada-Ebel, RuAngelie; Wray, Victor; Müller, Werner E. G.; Lin, Wenhan; Ebel, Rainer; Proksch, Peter
Source:
Zeitschrift für Naturforschung 2014 v.64 no.5-6 pp. 350-354
ISSN:
0939-5075
Subject:
Chaetomium; cytotoxicity; endophytes; fungi; growth retardation; median effective concentration; medicinal plants; mice; neoplasm cells; rice; spectral analysis; tetrahydrofuran
Abstract:
... A hitherto unidentified endophytic strain of the genus Chaetomium, isolated from the medicinal plant Otanthus maritimus, yielded a new tetrahydrofuran derivative, aureonitolic acid (), along with 5 known natural products, 2 - 6. The structure of 1 was determined by extensive spectroscopic analysis and comparison with reported data. Extracts of the fungus, grown either in liquid culture or on solid ...
DOI:
10.1515/znc-2009-5-608

4. Anti-Hepatitis B Virus Activity of New N4-β-D-Glycoside Pyrazolo[3,4-d]pyrimidine Derivatives

Author:
El-Sayed, Wael A.; Ramiz, Mahmoud M. M.; Abdel-Rahman, Adel A.-H.
Source:
Zeitschrift für Naturforschung 2014 v.64 no.5-6 pp. 323-328
ISSN:
1865-7125
Subject:
Hepatitis B virus; acetic anhydride; aldoses; antiviral properties; pyridines; pyrimidines; stereochemistry; urea; viruses
Abstract:
... The reaction of 6-hydrazinyl-1,3-dimethylpyrimidine-2,4-(1H,3H)-dione () with ethoxymethylenemalononitrile afforded 5-amino-1-(1,3-dimethyl-2,6-dioxo-1,2,3,6-tetrahydropyrimidin- 6-yl)-1H-pyrazole-4-carbonitrile (2). The latter was reacted with formamide and urea affording the corresponding 4-aminopyrazolo[3,4-d]pyrimidines 3 and 4. The reaction of monosaccharide aldoses with 3 and 4 gave stereose ...
DOI:
10.1515/znc-2009-5-603

5. Antimicrobial Activity of Gentiana lutea L. Extracts

Author:
Šavikin, Katarina; Menković, Nebojša; Zdunić, Gordana; Stević, Tatjana; Radanović, Dragoja; Janković, Teodora
Source:
Zeitschrift für Naturforschung 2014 v.64 no.5-6 pp. 339-342
ISSN:
0939-5075
Subject:
Candida albicans; Gentiana lutea; Gram-negative bacteria; Gram-positive bacteria; antibacterial properties; antifungal properties; flowers; high performance liquid chromatography; leaves; minimum inhibitory concentration; secondary metabolites; synergism; yeasts
Abstract:
... Methanolic extracts of flowers and leaves of Gentiana lutea L., together with the isolated compounds mangiferin, isogentisin and gentiopicrin, were used to investigate the antimicrobial activity of the plant. A variety of Gram-positive and Gram-negative bacteria as well as the yeast Candida albicans has been included in this study. Both extracts and isolated compounds showed antimicrobial activity ...
DOI:
10.1515/znc-2009-5-606

6. Bioactive Chemical Constituents and Comparative Antimicrobial Activity of Callus Culture and Adult Plant Extracts from Alternanthera tenella

Author:
Salvador, Marcos J.; Pereira, Paulo S.; França, Suzelei C.; Candido, Regina C.; Ito, Izabel Y.; Dias, Diones A.
Source:
Zeitschrift für Naturforschung 2014 v.64 no.5-6 pp. 373-381
ISSN:
1865-7125
Subject:
Alternanthera ficoidea; Gram-negative bacteria; antifungal properties; callus culture; chemical composition; chromatography; culture media; flavonoids; fractionation; keratinophilic fungi; mature plants; minimum inhibitory concentration; nuclear magnetic resonance spectroscopy; plant extracts; saponins; steroids; yeasts
Abstract:
... Crude extracts of a callus culture (two culture media) and adult plants (two collections) from Alternanthera tenella Colla (Amaranthaceae) were evaluated for their antibacterial and antifungal activity, in order to investigate the maintenance of antimicrobial activity of the extracts obtained from plants in vivo and in vitro. The antibacterial and antifungal activity was determined against thirty ...
DOI:
10.1515/znc-2009-5-612

7. Cassiaindoline, a New Analgesic and Anti-Infl ammatory Alkaloid from Cassia alata

Author:
Villaseñor, Irene M.; Sanchez, Arlyn C.
Source:
Zeitschrift für Naturforschung 2014 v.64 no.5-6 pp. 335-338
ISSN:
1865-7125
Subject:
Senna alata; acetic acid; analgesic effect; analgesics; anti-inflammatory activity; indole alkaloids; leaves; mice; spectral analysis
Abstract:
... Cassiaindoline is a new dimeric indole alkaloid isolated from Cassia alata L. leaves whose structure was elucidated through spectroscopic analyses. It exhibited analgesic activity at a dosage of 125.0 mg/kg mouse and decreased the number of writhings induced by acetic acid by 49.4%. It also showed a 57.1% anti-inflammatory activity at a dosage of 75 mg/kg mouse ...
DOI:
10.1515/znc-2009-5-605

8. Cell Viability and Leakage of Electrolytes in Avicennia germinans Exposed to Heavy Metals

Author:
Gonzalez-Mendozaa, Daniel; Quiroz-Moreno, Adriana; Medrano, Rosa Escobedo Gracia; Grimaldo-Juareza, Onecimo; Zapata-Perez, Omar
Source:
Zeitschrift für Naturforschung 2014 v.64 no.5-6 pp. 391-394
ISSN:
1865-7125
Subject:
Avicennia germinans; cadmium; cell membranes; cell viability; copper; electrolytes; heavy metals; histology; intercellular spaces; leaves; mesophyll
Abstract:
... The effect of heavy metal stress on the cell viability and leakage of electrolytes of Avicennia germinans leaf discs was investigated by the tissue tolerance test. Foliar discs were incubated with different Cd²⁺ or Cu²⁺ concentrations for 24 h; thereafter, the cell membrane stability of the tissue was assayed by the cell viability Evans blue and leakage electrolytes methods. The results indicated ...
DOI:
10.1515/znc-2009-5-615

9. Co-Production of Bisphenylpropanoid Amides and Meroterpenes by an Endophytic Penicillium brasilianum Found in the Root Bark of Melia azedarach

Author:
Fill, Taicia P.; Santos, Regina M. Geris dos; Barisson, Anderson; Rodrigues-Filho, Edson; Souza, Antonia Q. L.
Source:
Zeitschrift für Naturforschung 2014 v.64 no.5-6 pp. 355-360
ISSN:
0939-5075
Subject:
Melia azedarach; Penicillium brasilianum; amides; antimicrobial properties; bacteria; bark; chromatography; endophytes; fungi; internal transcribed spacers; nitrogen; nuclear magnetic resonance spectroscopy; ribosomal DNA; rice; stable isotopes
Abstract:
... A fungus, isolated from the root bark of Melia azedarach (Meliaceae), from which a series of meroterpenes have been reported, was identified as Penicillium brasilianum based on analysis of the ITS region of ribosomal DNA. From a rice culture of this fungus, the known phenylpropanoid amides brasiliamide A and B were obtained together with and a new, slightly modified congener, along with the merote ...
DOI:
10.1515/znc-2009-5-609

10. Cytotoxicity of Vincristine on the 5637 Cell Line Is Enhanced by Combination with Conferone

Author:
Neshatia, Vajiheh; Matin, Maryam M.; Iranshahi, Mehrdad; Bahrami, Ahmad R.; Behravan, Javad; Mollazadeh, Samaneh; Rassouli, Fatemeh Behnam
Source:
Zeitschrift für Naturforschung 2014 v.64 no.5-6 pp. 317-322
ISSN:
1865-7125
Subject:
Ferula; adenocarcinoma; coumarin; cytotoxicity; developed countries; histology; neoplasm cells; sesquiterpenoids; squamous cell carcinoma; urinary bladder neoplasms; vincristine
Abstract:
... Bladder cancer is one of the most common cancers worldwide, with the highest incidence in industrialized countries. There are three major histological subtypes of bladder cancer: transitional cell carcinoma (TCC) (>90%), squamous cell carcinoma (<10%) and adenocarcinoma (1 - 2%). The present study was carried out to assess the effects of conferone, a sesquiterpene coumarin isolated from Ferula bad ...
DOI:
10.1515/znc-2009-5-602

11. Effect of DNA Methylation on 18S rRNA Gene Sequences during Culture of Taxus chinensis Cells

Author:
Xiang, Fu; Li, Liqing; Jin, Wenwen; Yu, Longjiang
Source:
Zeitschrift für Naturforschung 2014 v.64 no.5-6 pp. 418-420
ISSN:
0939-5075
Subject:
DNA methylation; Taxus wallichiana var. chinensis; antineoplastic agents; cell suspension culture; genes; new variety; nucleotide sequences; paclitaxel; phylogeny; ribosomal RNA
Abstract:
... Cell suspension culture has rapidly become an alternative source of taxol, an anticancer compound. To investigate the role of DNA methylation in the cultural course of Taxus chinensis cells, analyses of 18S rRNA gene sequences of cultured T. chinensis cells and related species were conducted. The phylogenetic analysis of 18S rRNA gene sequences indicated that HG-1 (the cultured T. chinensis cells) ...
DOI:
10.1515/znc-2009-5-620

12. Effects of Limonoids from Cipadessa fruticosa on Fall Armyworm

Author:
Matos, Andreia P.; Leite, Ana C.; Batista-Pereira, Luciane G.; Vieira, Paulo C.; Fernandes, João B.; Silva, Maria Fátima das G. F. da
Source:
Zeitschrift für Naturforschung 2014 v.64 no.5-6 pp. 441-446
ISSN:
1865-7125
Subject:
Meliaceae; Spodoptera frugiperda; antifeeding activity; artificial diets; chemical structure; fruits; growth retardation; insecticidal properties; limonoids; methylene chloride; mortality; neonates
Abstract:
... Six mexicanolide limonoids isolated from the dichloromethane extract of the fruits of Cipadessa fruticosa Blume (Meliaceae) were evaluated against Spodoptera frugiperda (J. E. Smith). Gedunin was used as a positive control. When incorporated into an artificial diet of neonates at 50.0 mg kg⁻¹, febrifugin A showed 73.3% mortality. All the compounds showed moderate insecticidal activity, except for ...
DOI:
10.1515/znc-2009-5-623

13. Ethylamine Content and Theanine Biosynthesis in Different Organs of Camellia sinensis Seedlings

Author:
Deng, Wei-Wei; Ogita, Shinjiro; Ashihara, Hiroshi
Source:
Zeitschrift für Naturforschung 2014 v.64 no.5-6 pp. 387-390
ISSN:
1865-7125
Subject:
Camellia sinensis; alanine; biosynthesis; cotyledons; glutamic acid; leaves; roots; seedlings; stems; tea; theanine
Abstract:
... We examined the distribution of ethylamine, glutamic acid and alanine, which are utilized in theanine biosynthesis, and other major amino acids in leaves, stems, cotyledons and roots of 6-week-old tea seedlings. Ethylamine and glutamic acid, which are substrates of theanine synthetase, were distributed almost uniformly in all parts of the seedlings; the contents in μmol/g fresh wt varied from 0.44 ...
DOI:
10.1515/znc-2009-5-614

14. Hepatoprotective and Antioxidant Activity of Two Iridoids from Mussaenda ‘dona aurora’

Author:
Vidyalakshmi, Kandulva Sethuraman; Nagarajan, Sulochana; Vasanthi, Hannah Rachel; Venkappaya,; Rajamanickam, Victor
Source:
Zeitschrift für Naturforschung 2014 v.64 no.5-6 pp. 329-334
ISSN:
0939-5075
Subject:
Mussaenda; alanine transaminase; antioxidant activity; aspartate transaminase; blood serum; calyx; ethyl acetate; hepatoprotective effect; iridoids; silymarin
Abstract:
... Mussaenda ‘dona aurora’ (sepals) has been investigated for its hepatoprotective and antioxidant activities. The highest activity was observed in the ethyl acetate fraction. The separation of the ethyl acetate fraction gave two iridoids, sanshiside-D and lamalbide. Sanshiside-D exhibited a hepatoprotective activity greater than silimarin as was evidenced by significant reduction of ALT and AST in t ...
DOI:
10.1515/znc-2009-5-604

15. Immunomodulatory and Anti-Inflammatory Activity of Selected Osthole Derivatives

Author:
Zimecki, Michał; Artym, Jolanta; Cisowski, Wojciech; Mażol, Irena; Włodarczyk, Maciej; Glenśk, Michał
Source:
Zeitschrift für Naturforschung 2014 v.64 no.5-6 pp. 361-368
ISSN:
1865-7125
Subject:
Peucedanum; Phytolacca americana; amides; anti-inflammatory activity; chlorides; chromium; erythrocytes; humans; humoral immunity; inflammation; interleukin-6; lipopolysaccharides; mice; models; mononuclear leukocytes; oxidation; piperidines; rats; roots; sheep; splenocytes; tumor necrosis factors
Abstract:
... From osthole [7-methoxy-8-(3-methyl-but-2-enyl)-chromen-2-one] (), obtained by selective extraction of Peucedanum ostruthium (L.) W. Koch roots, ostholic acid (II) was synthetized as a result of its oxidation with chromium trioxide. From ostholic acid, through its chloride, four amides were obtained: the morpholide 1, the p-chloro-benzylamide 2, the piperidine 3 and the N-methyl-piperazide 4. Exce ...
DOI:
10.1515/znc-2009-5-610

16. Inhibitors of ABC Transporters and Biophysical Methods to Study their Activity

Author:
Bartosiewicz, Dominika; Krasowska, Anna
Source:
Zeitschrift für Naturforschung 2014 v.64 no.5-6 pp. 454-458
ISSN:
1865-7125
Subject:
ABC transporters; Saccharomyces cerevisiae; adenosine triphosphate; antineoplastic agents; energy; fluorescent dyes; hydrolysis; mammals; models; multiple drug resistance; neoplasm cells; neoplasms; therapeutics; yeasts
Abstract:
... Multidrug resistance caused by the presence and overproduction of ABC transporters makes serious problems in cancer treating. The drugs administered during therapy are pumped outside the cell using the energy obtained from ATP hydrolysis. The augmented dosage of drugs to overcome the multidrug resistance is not sufficient. Thus knowledge of the structure of ABC proteins is necessary to understand ...
DOI:
10.1515/znc-2009-5-625

17. Isolation and Characterization of New Metschnikowia pulcherrima Strains as Producers of the Antimicrobial Pigment Pulcherrimin

Author:
Türkel, Sezai; Ener, Beyza
Source:
Zeitschrift für Naturforschung 2014 v.64 no.5-6 pp. 405-410
ISSN:
0939-5075
Subject:
Aspergillus fumigatus; Aspergillus niger; Bipolaris; Candida albicans; Candida krusei; Candida parapsilosis; Escherichia coli; Metschnikowia pulcherrima; Paecilomyces; Proteus vulgaris; Trichoderma; Trichosporon; animal pathogens; antimicrobial properties; biological control; culture media; grapes; yeasts
Abstract:
... Metschnikowia pulcherrima is a highly effective biocontrol yeast due to its pigment pulcherrimin that accumulates in the cells and in the growth medium. Three different strains of M. pulcherrima were isolated from local grapes. The yeast isolates were characterized on the basis of their biochemical, physiological and ITS1-5.8 s rDNA-ITS2 region. Based on the obtained results, the M. pulcherrima is ...
DOI:
10.1515/znc-2009-5-618

18. Lipophilic Compounds from the Femoral Gland Secretions of Male Hungarian Green Lizards, Lacerta viridis

Author:
Kopena, Renata; López, Pilar; Martín, José
Source:
Zeitschrift für Naturforschung 2014 v.64 no.5-6 pp. 434-440
ISSN:
1865-7125
Subject:
steroids; lactones; lizards; Lacerta; males; phylogeny; reproductive behavior; alpha-tocopherol; environmental factors; squalene; pheromones; alcohols; carboxylic acids; gas chromatography-mass spectrometry
Abstract:
... In spite of the importance of chemical signals (pheromones) in the reproductive behaviour of lizards, only a few studies have examined the role of specific chemical compounds as sexual signals. The secreted chemicals vary widely between species but whether this variation reflects phylogenetic or environmental differences remains unclear. Based on mass spectra, obtained by GC-MS, we found 40 lipoph ...
DOI:
10.1515/znc-2009-5-622

19. Micro-Particle Transporting System Using Galvanotactically Stimulated Apo-Symbiotic Cells of Paramecium bursaria

Author:
Furukawa, Shunsuke; Karaki, Chiaki; Kawano, Tomonori
Source:
Zeitschrift für Naturforschung 2014 v.64 no.5-6 pp. 421-433
ISSN:
1865-7125
Subject:
Chlorophyta; Escherichia coli; Paramecium bursaria; algae; anodes; calcium channels; cell movement; crystals; electric field; green fluorescent protein; oxides; plasma membrane; polystyrenes; zeolites
Abstract:
... It is well known that Paramecium species including green paramecia (Paramecium bursaria) migrate towards the anode when exposed to an electric field in a medium. This type of a cellular movement is known as galvanotaxis. Our previous study revealed that an electric stimulus given to P. bursaria is converted to a galvanotactic cellular movement by involvement of T-type calcium channel on the plasma ...
DOI:
10.1515/znc-2009-5-621

20. Neuroprotective and Neurotrophic Effects of Isorosmanol

Author:
Park, So-Young
Source:
Zeitschrift für Naturforschung 2014 v.64 no.5-6 pp. 395-398
ISSN:
0939-5075
Subject:
Alzheimer disease; actin; cell death; death; diterpenoids; nerve growth factor; neurites; neurotoxicity; synapse
Abstract:
... The neurotoxicity induced by beta-amyloid (Aβ), which is one of the major causes of Alzheimer’s disease (AD), leads to synaptic loss and subsequent neuronal death. Therefore, modulation of Aβ-induced neurotoxicity, as well as regeneration of damaged synapses could be important therapeutic approaches to control AD. In this study, we found that isorosmanol, an abietane-type diterpene, protected PC12 ...
DOI:
10.1515/znc-2009-5-616