Journal: Zeitschrift für Naturforschung / Subject: Bulgaria and acetylcholinesterase

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Author:: Vrancheva, Radka Z.; Ivanov, Ivan G.; Aneva, Ina Y.; Dincheva, Ivayla N.; Badjakov, Ilian K.; Pavlov, Atanas I.
Source:: Zeitschrift für Naturforschung 2016 v.71 no.1-2 pp. 9-14
ISSN:: 1865-7125
Subject:: Fumaria; acetylcholinesterase; gas chromatography-mass spectrometry; high performance liquid chromatography; inhibitory concentration 50; isoquinoline alkaloids; Bulgaria
Abstract:: ... GC-MS analysis of alkaloid profiles of five Fumaria species, naturally grown in Bulgaria (F. officinalis, F. thuretii, F. kralikii, F. rostellata and F. schrammii) and analysis of acetylcholinesterase inhibitory activity of alkaloid extracts were performed. Fourteen isoquinoline alkaloids were identified, with the principle ones being protopine, cryptopine, sinactine, parfumine, fumariline, fumaro ...
DOI:: 10.1515/znc-2014-4179
: http://dx.doi.org/10.1515/znc-2014-4179

Author:: Georgievaa, Liliya; Berkov, Strahil; Kondakova, Violeta; Bastida, Jaume; Viladomat, Francesc; Atanassov, Atanas; Codina, Carles
Source:: Zeitschrift für Naturforschung 2014 v.62 no.9-10 pp. 627-635
ISSN:: 1865-7125
Subject:: Alzheimer disease; Leucojum aestivum; acetylcholinesterase; bulbs; gas chromatography-mass spectrometry; lycorine; summer; Bulgaria
Abstract:: ... Leucojum aestivum (summer snowflake) is a plant species used for the extraction of galanthamine, an acetylcholinesterase inhibitor for the treatment of Alzheimer’s disease. Extracts from bulbs collected from 18 Bulgarian populations and from shoot-clumps obtained in vitro from 8 different populations showed variations in their alkaloid composition. Nineteen alkaloids were detected in the studied s ...
DOI:: 10.1515/znc-2007-9-1002
: http://dx.doi.org/10.1515/znc-2007-9-1002