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- Freeman, Megan Culler; Peek, Christopher T.; Becker, Michelle M.; Smith, Everett Clinton; Denison, Mark R.
- mBio 2014 v.5 no.4 pp. e01340-14
- Murine hepatitis virus, etc ; cell fusion; epidermal growth factor receptors; giant cells; humans; pathogenesis; pathogens; pseudopodia; surface proteins; viral load; virus replication; viruses; Middle East; Show all 13 Subjects
- ... Macropinocytosis is exploited by many pathogens for entry into cells. Coronaviruses (CoVs) such as severe acute respiratory syndrome (SARS) CoV and Middle East respiratory syndrome CoV are important human pathogens; however, macropinocytosis during CoV infection has not been investigated. We demonstrate that the CoVs SARS CoV and murine hepatitis virus (MHV) induce macropinocytosis, which occurs l ...
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