U.S. flag

An official website of the United States government

Dot gov

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Https

Secure .gov websites use HTTPS
A lock ( ) or https:// means you’ve safely connected to the .gov website. Share sensitive information only on official, secure websites.

PubAg

Main content area

You searched for: Publication year rev 7978-2022 Remove constraint Publication year rev: 7978-2022 Source 2022 Remove constraint Source: 2022
Start Over

Search

5,662  Search Results

« Previous | 1 - 20 of 5,662 |
Number of results to display per page

Search Results

1. (Re) thinking Towards a Sustainable Analytical Chemistry: Part I: Inorganic Elemental Sample Treatment, Part II: Alternative Solvents and Extraction Techniques

Author:
Ana P.R. Santana; Patricia de Andrade Nascimento; Taciana G.S. Guimarães; Iohanna M.N. Ribeiro Menezes; Daniel F. Andrade; Andrea Oliveira; Mario H. Gonzalez
Source:
Trends in analytical chemistry 2022 pp. 116596
ISSN:
0165-9936
Subject:
Raman spectroscopy; X-radiation; alkali treatment; atomic absorption spectrometry; chemical analysis; chemometrics; combustion; digestion; fluorescence; liquid-liquid extraction; microwave treatment; toxicity; ultrasonic treatment; ultraviolet radiation
Abstract:
... Currently, there is a huge demand for the development of analytical methods for chemical analysis. Sustainable methods have aroused the interest of researchers in the last years. This paper reviews important technologies for digestion and solid-liquid extraction approaches, with emphasis in emerging greener methods for the elemental analysis of different samples. Analytical technologies such as Mi ...
DOI:
10.1016/j.trac.2022.116596

2. (−)-Epicatechin Ameliorates Cardiac Fibrosis in a Female Rat Model of Pre-Heart Failure with Preserved Ejection Fraction

Author:
Moises Bustamante-Pozo; Israel Ramirez-Sanchez; Alejandra Garate-Carrillo; Bruce Ito; Viridiana Navarrete; Moises Haro; Ricardo Garcia; Nancy Carson; Guillermo Ceballos; Francisco Villarreal
Source:
Journal of medicinal food 2022 pp. -
ISSN:
1557-7600
Subject:
animal models; catheters; collagen; cytokines; females; fibrosis; flavonoids; functional foods; hemodynamics; infarction; inflammation; ischemia; oxidative stress; rodents
Abstract:
... One of the most abundant flavonoids present in cacao is (−)-epicatechin (Epi) and this flavanol has been linked to the cardiovascular health promoting actions of cocoa products. We previously demonstrated that Epi reduces infarct size in rodent models of ischemia/reperfusion and permanent coronary occlusion. Reduced infarct size was associated with decreased left ventricular (LV) oxidative stress ...
DOI:
10.1089/jmf.2021.0158

3. 1,3-Dipolar cycloaddition reactions of enaminones and azides: Synthesis of 4-acyl-1,2,3-triazoles and mechanistic studies

Author:
Francisco V. Gaspar; Marcelo F.M.F. Azevedo; Leonardo S.A. Carneiro; Samuel B. Ribeiro; Pierre M. Esteves; Camilla D. Buarque
Source:
Tetrahedron 2022 pp. 132856
ISSN:
0040-4020
Subject:
azides; cycloaddition reactions; reaction mechanisms
Abstract:
... 4-acyl-1,2,3-triazoles are an important and versatile chemical scaffold widely applied in medicinal chemists due to their interesting pharmacological properties. Acknowledging the constant need for a greener, simple and scalable methodology in medicinal chemistry, herein we report the synthesis of new 4-acyl-1,2,3-triazoles through the metal-free and solvent-free cycloaddition reactions between en ...
DOI:
10.1016/j.tet.2022.132856

4. 137Cs tracing of the spatial patterns in soil redistribution, organic carbon and total nitrogen in the southeastern Tibetan Plateau

Author:
Zhengan Su; Lijuan Wang; Yihan Liu; Bin Fu; Jianhui Zhang; Zuo Wu; Tao Zhou; Junjie Wang
Source:
International soil and water conservation research 2022 pp. -
ISSN:
2095-6339
Subject:
agricultural land; biodiversity; cesium radioisotopes; climate; freeze-thaw cycles; grasslands; gully erosion; humans; inventories; research; soil; soil organic carbon; temperature; terracing; tillage erosion; total nitrogen; water conservation; wind erosion; China
Abstract:
... The southeastern Tibetan Plateau, which profoundly affects East Asia by helping to maintain the stability of climate systems, biological diversity and clean water, is one of the regions most vulnerable to water erosion, wind erosion, tillage erosion, freeze–thaw erosion and overgrazing under global climate changes and intensive human activities. Spatial variations in soil erosion in terraced farml ...
DOI:
10.1016/j.iswcr.2022.05.001

5. 13C metabolic flux analysis clarifies distinct metabolic phenotypes of cancer cell spheroid mimicking tumor hypoxia

Author:
Shingo Noguchi; Kenichi Wakita; Fumio Matsuda; Hiroshi Shimizu
Source:
Metabolic engineering 2022 pp. -
ISSN:
1096-7176
Subject:
energy metabolism; glutaminase; hypoxia; metabolic flux analysis; models; neoplasm cells; neoplasm progression; neoplasms; principal component analysis; protein synthesis; pyruvate carboxylase
Abstract:
... Cancer cells adapt their intracellular energy metabolism to the oxygen-deprived tumor microenvironment (TME) to ensure tumor progression. This adaptive mechanism has focused attention on the metabolic phenotypes of tumor cells under hypoxic TME for developing novel cancer therapies. Although widely used monolayer (2D) culture does not fully reflect in vivo hypoxic TME, spheroid (3D) culture can pr ...
DOI:
10.1016/j.ymben.2022.07.008

6. A 1600-year record of eolian activity from Jili Lake in northern Xinjiang

Author:
Mingrui Qiang; Wenzhe Lang; Zhenhao He; Ming Jin; Aifeng Zhou; Jiawu Zhang
Source:
Quaternary international 2022 pp. -
ISSN:
1040-6182
Subject:
North Atlantic Oscillation; air; arid zones; atmospheric circulation; carbon radioisotopes; cold; dust; dust emissions; lakes; sand; sand fraction; silt; spatial variation; spring; surface area; watersheds; wind erosion; wind speed; Central Asia; China
Abstract:
... Eolian activity determines the magnitude of dust emission. However, geological records of eolian activity are scarce due to strong wind erosion in the dust source areas. Northern Xinjiang is recognized as a major dust source region in arid central Asia. Here we present a lacustrine record of eolian activity over the past 1600 years from Jili Lake, in northern Xinjiang, which acts a natural trap fo ...
DOI:
10.1016/j.quaint.2022.05.012

7. 17β-estradiol inhibits vascular proliferation and inflammation by reducing NF-κB expression induced by increased crosstalk between KLF5 and ERα

Author:
Man-li Zhang; Man-na Zhang; Wen-li Wang; Hui Chen; Xia Wang; Xuan Li; Li Li; Fei Tong
Source:
Biochemical and biophysical research communications 2022 pp. -
ISSN:
0006-291X
Subject:
Western blotting; cardiovascular system; cell proliferation; chromatin immunoprecipitation; fluorescent antibody technique; inflammation; luciferase; research; smooth muscle
Abstract:
... Pathological vascular remodeling and cell proliferation play vital roles in many proliferative vascular diseases. Estrogen can protect the cardiovascular system, but its exact molecular mechanism is unknown. Here we report that 17β-estradiol (E2) suppressed vascular smooth muscle cells (VSMCs) proliferation and inflammation. qRT-PCR and western blot demonstrated that E2 decreased NF-κB p50 express ...
DOI:
10.1016/j.bbrc.2022.07.054

8. An 18-country analysis of the effectiveness of five front-of-pack nutrition labels

Author:
Simone Pettigrew; Michelle Jongenelis; Alexandra Jones; Serge Hercberg; Chantal Julia
Source:
Food quality and preference 2022 pp. 104691
ISSN:
0950-3293
Subject:
food quality; steers; traffic
Abstract:
... Various front-of-pack food labels (FoPLs) are being introduced across the world, and discussion continues about the most effective label formats to improve consumers’ (i) understanding of the relative healthiness of alternative products and (ii) product choices. Of increasing interest is the relative ability of different types of labels to steer consumers away from unhealthy options (aversion) ver ...
DOI:
10.1016/j.foodqual.2022.104691

9. IL- 1β induced by PRRSV co-infection inhibited CSFV C-strain proliferation via the TLR4/NF-κB/MAPK pathways and the NLRP3 inflammasome

Author:
Dengjin Chen; Shengkui Xu; Ruijiao Jiang; Yating Guo; Xintan Yang; Yongning Zhang; Lei Zhou; Xinna Ge; Jun Han; Xin Guo; Hanchun Yang
Source:
Veterinary microbiology 2022 pp. 109513
ISSN:
0378-1135
Subject:
antibodies; industry; inflammasomes; mixed infection; porcine reproductive and respiratory syndrome; swine; vaccination; vaccines; viruses
Abstract:
... PRRSV and CSFV are both the main pathogens of pigs and pose great threats to the pig industry. Previous studies have shown that PRRSV infection or attenuated virus vaccination can reduce the antibody level of attenuated CSFV vaccine and even cause immune failure. The higher pro-inflammatory cytokines induced by PRRSV might play a significant role in inhibiting the proliferation of CSFV-C. However, ...
DOI:
10.1016/j.vetmic.2022.109513

10. 2,3-Butanediol from the leachates of pine needles induces the resistance of Panax notoginseng to the leaf pathogen Alternaria panax

Author:
Tian-Yao Li; Chen Ye; Yi-Jie Zhang; Jun-Xing Zhang; Min Yang; Xia-Hong He; Xin-Yue Mei; Yi-Xiang Liu; You-Yong Zhu; Hui-Chuan Huang; Shu-Sheng Zhu
Source:
Plant diversity 2022 pp. -
ISSN:
2468-2659
Subject:
Alternaria panax; Panax notoginseng; Pinus armandii; RNA; biosynthesis; disease control; foliar diseases; gas chromatography-mass spectrometry; immunity; jasmonic acid; mitogen-activated protein kinase; pathogens; sequence analysis; species diversity; systemic acquired resistance; transcription factors
Abstract:
... Compared with the use of monocultures in the field, cultivation of medicinal herbs in forests is an effective strategy to alleviate disease. Chemical interactions between herbs and trees play an important role in disease suppression in forests. We evaluated the ability of leachates from needles of Pinus armandii to induce resistance in Panax notoginseng leaves, identified the components via gas ch ...
DOI:
10.1016/j.pld.2022.02.003

11. 20,000 years of small game hunting in southern Somalia

Author:
Mica B. Jones; Steven A. Brandt
Source:
Quaternary international 2022 pp. -
ISSN:
1040-6182
Subject:
Phacochoerus; Tragelaphus; fauna; land use; lizards; occupations; paleoclimatology; Somalia
Abstract:
... Archaeologists relate increasing forager reliance on small animals and broad-spectrum resource use to environmental and demographic changes in temperate regions during Marine Isotope Stage (MIS) 2, 29-14.7 thousand years ago (ka), and MIS 1, after 14.7 ka. However, little research has examined the factors that influenced small game hunting in the arid and semi-arid tropics of eastern Africa during ...
DOI:
10.1016/j.quaint.2022.06.004

12. 2D hybrid photocatalysts for solar energy harvesting

Author:
Ali Raza; Asma Rafiq; Usman Qumar; Jahan Zeb Hassan
Source:
Sustainable materials and technologies 2022 pp. e00469
ISSN:
2214-9937
Subject:
adsorption; desalination; graphene; hybridization; photocatalysis; photocatalysts; remediation; solar energy; surface area
Abstract:
... In recent years, the process of photocatalytic degradation is considered as one of the outstanding strategies for removing pollutants from aqueous solutions than traditional adsorption. The wide-ranging band structures, sufficient active sites, and significant specific surface area of 2D materials offer them a significant amount of potential as an effective photocatalyst in the degradation of cont ...
DOI:
10.1016/j.susmat.2022.e00469

13. 3D coupled FEM-IBIEM for non-linear seismic response of a sedimentary basin using equivalent-linearized soil model

Author:
Zhong-xian Liu; Jun Sun; Si-bo Meng; Ting Feng; Lei Huang; Hu Li
Source:
Computers & geosciences 2022 pp. 105199
ISSN:
0098-3004
Subject:
basins; equations; finite element analysis; geophysics; models; soil
Abstract:
... Based on an equivalent-linearized dynamic constitutive model of the soil, the coupled finite element method - indirect boundary integral equation method (FEM-IBIEM) is developed to carry out the non-linear seismic response of a three-dimensional (3-D) sedimentary basin. The indirect boundary integral equation method (IBIEM), which can significantly reduce the solution dimension, is employed to sol ...
DOI:
10.1016/j.cageo.2022.105199

14. 5-HT and α-m-5-HT attenuate excitatory synaptic transmissions onto the lateral amygdala principal neurons via presynaptic 5-HT1B receptors

Author:
Ryo Yamamoto; Tetsufumi Ito; Takafumi Furuyama; Munenori Ono; Nobuo Kato
Source:
Biochemical and biophysical research communications 2022 pp. -
ISSN:
0006-291X
Subject:
agonists; amygdala; antagonists; rats; research; serotonin; serotonin receptors; therapeutics
Abstract:
... Accumulating evidence suggests that the serotonergic (5-HT) system in the amygdala has significant effects on affective states. Dysregulation of the 5-HT system in the basolateral amygdaloid complex causes affective disorders. To search for therapeutic targets, subtype specification of 5-HT receptors is crucial. The present study was undertaken to identify the 5-HT receptor subtype responsible for ...
DOI:
10.1016/j.bbrc.2022.07.076

15. 6700 years of diatom changes related to land use and climatic fluctuations in the Lake Aydat catchment (Auvergne, France): Coupling with cyanobacteria akinetes, pollen and non-pollen palynomorphs data

Author:
Aude Beauger; Karen Serieyssol; Benjamin Legrand; Delphine Latour; Vincent Berthon; Marlène Lavrieux; Yannick Miras
Source:
Quaternary international 2022 pp. -
ISSN:
1040-6182
Subject:
Aulacoseira; Bacillariophyceae; Cannabis sativa; Cyanobacteria; Stephanodiscus; eutrophication; hemp; humans; lakes; land use; landscapes; livestock; plankton; pollen; tourism; water quality; watersheds; France
Abstract:
... Nowadays Lake Aydat is an important site for tourism activities but blooms of cyanobacteria induced some restriction for aquatic activities by humans and their livestock. Thus, it was important to understand the lake's history as it should help in the development of restoration strategies to improve water quality in the future. Lake Aydat had a complex history affected by climatic changes and huma ...
DOI:
10.1016/j.quaint.2022.01.013

16. 7-aminocephalosporanic acid, a novel HSP90β inhibitor, attenuates HFD-induced hepatic steatosis

Author:
Weitao Zhang; Hanyue Xue; Chen Zhou; Zuguo Zheng; Mingming Xing; Hang Chu; Ping Li; Naixia Zhang; Yongjun Dang; Xiaojun Xu
Source:
Biochemical and biophysical research communications 2022 pp. -
ISSN:
0006-291X
Subject:
adipose tissue; antibiotics; blood serum; cholesterol; fatty liver; heat-shock protein 90; liver; microarray technology; research; triacylglycerols
Abstract:
... Hepatic steatosis is one of the most important causes of liver disease worldwide. Heat shock protein 90 (HSP90) is essential for numerous client proteins. Recently, more attention was focused on increased HSP90 levels in hepatic steatosis, especially HSP90β. Thus, great efforts have been made to develop HSP90β inhibitors, and most natural inhibitors are derived from microorganisms. In this study, ...
DOI:
10.1016/j.bbrc.2022.07.033

17. An 8-month longitudinal exploration of body image and disordered eating in the UK during the COVID-19 pandemic

Author:
Helen Sharpe; Emily Newman; Mackenzie D.A. Robertson; Marie-Christine Opitz; Imogen Peebles; Fiona Duffy
Source:
Eating behaviors 2022 pp. 101660
ISSN:
1471-0153
Subject:
COVID-19 infection; body image; distress; gender; longitudinal studies; mental health; pandemic
Abstract:
... Research suggests that the COVID-19 pandemic is negatively impacting mental health, with rates of eating disorder referrals in particular rising steeply during the pandemic. This study aimed to examine 8-month changes in body image and disordered eating during the COVID-19 pandemic, and explore whether any changes were moderated by gender, age, or eating disorder history. This study used a longitu ...
DOI:
10.1016/j.eatbeh.2022.101660

18. 8th century coastal uplift in Peninsular India – The Shore Temple at Mahabalipuram, Tamil Nadu

Author:
Miklós Kázmér; Siddharth Prizomwala; Krzysztof Gaidzik
Source:
Quaternary international 2022 pp. -
ISSN:
1040-6182
Subject:
coasts; earthquakes; liquefaction; sea level; subsoil; India
Abstract:
... The Shore Temple in Mahabalipuram (Tamil Nadu, Southern India) exists since the late 7th century. Historical sources suggest that it was built on an island in honour of the gods Vishnu and Shiva. A former bridge over the canal, which separated the island from the mainland, and a seawall, which protected the shore from the waves are dysfunctional now, as they are located too high above the present ...
DOI:
10.1016/j.quaint.2022.02.014

19. ABCG2/BCRP transport mechanism revealed through kinetically excited targeted molecular dynamics simulations

Author:
B. Dudas; X. Decleves; S. Cisternino; D. Perahia; M.A. Miteva
Source:
Computational and Structural Biotechnology Journal 2022 pp. -
ISSN:
2001-0370
Subject:
ABC transporters; biotechnology; drugs; estrone; exports; molecular dynamics; multiple drug resistance; xenobiotics
Abstract:
... ABCG2/BCRP is an ABC transporter that plays an important role in tissue protection by exporting endogenous substrates and xenobiotics. ABCG2 is of major interest due to its involvement in multidrug resistance (MDR), and understanding its complex efflux mechanism is essential to preventing MDR and drug-drug interactions (DDI). ABCG2 export is characterized by two major conformational transitions be ...
DOI:
10.1016/j.csbj.2022.07.035

20. An AHP-GIS based site suitability analysis for integrating large-scale hybrid CSP+PV plants in Morocco: An approach to address the intermittency of solar energy

Author:
Ouafae Jbaihi; Fatima-zahra Ouchani; Ahmed Alami Merrouni; Mohamed Cherkaoui; Abdellatif Ghennioui; Mohammed Maaroufi
Source:
Journal of cleaner production 2022 pp. 133250
ISSN:
0959-6526
Subject:
cooling; electricity; feasibility studies; geographic information systems; hybridization; issues and policy; prices; risk; solar energy; solar farms; thermal energy; Morocco
Abstract:
... Greater integration of solar energy into the worldwide energy mix is increasingly ineluctable and implies a proper site selection. Photovoltaic (PV) is economically more considerable due to its falling price, but storage issues arise with large-scale integration and might be tackled with Concentrated Solar Power (CSP) considering its thermal energy storage (TES) system. CSP + PV hybridization may ...
DOI:
10.1016/j.jclepro.2022.133250