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You searched for: Publication year rev 7980-2020 Remove constraint Publication year rev: 7980-2020 Subject term antioxidants Remove constraint Subject term: antioxidants
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1. (Ascorb)ing Pb Neurotoxicity in the Developing Brain

Author:
Faraz Ahmad; Ping Liu
Source:
Antioxidants 2020 v.9 no.12 pp. -
ISSN:
2076-3921
Subject:
antioxidants; ascorbic acid; brain; children; homeostasis; humans; lead; lead poisoning; metal ions; neurotoxicity; nutrients; research; therapeutics; trajectories
Abstract:
... Lead (Pb) neurotoxicity is a major concern, particularly in children. Developmental exposure to Pb can alter neurodevelopmental trajectory and has permanent neuropathological consequences, including an increased vulnerability to further stressors. Ascorbic acid is among most researched antioxidant nutrients and has a special role in maintaining redox homeostasis in physiological and physio-patholo ...
DOI:
10.3390/antiox9121311

2. (Bio)Technological aspects of microalgae pigments for cosmetics

Author:
Ana Lucía Morocho-Jácome; Nadia Ruscinc; Renata Miliani Martinez; João Carlos Monteiro de Carvalho; Tânia Santos de Almeida; Catarina Rosado; João Guilherme Costa; Maria Valéria Robles Velasco; André Rolim Baby
Source:
Applied microbiology and biotechnology 2020 v.104 no.22 pp. 9513-9522
ISSN:
0175-7598
Subject:
Cyanobacteria; allergenicity; antioxidants; astaxanthin; biotechnology; carbon dioxide; chlorophyll; cosmetics; industry; markets; microalgae; photosynthesis; phycobiliprotein; solar radiation; xanthophylls
Abstract:
... Photosynthetic microorganisms convert carbon dioxide and solar radiation into interesting bioactive compounds not yet entirely explored. Several species of microalgae are known to be rich in colored high-valuable components that, although remarkable, are poorly explored as natural sources of pigments for cosmetics. Pigments associated to photosynthetic activity include chlorophyll, β-carotene, ast ...
DOI:
10.1007/s00253-020-10936-x

3. (–)-β-Homoarginine anhydride, a new antioxidant and tyrosinase inhibitor, and further active components from Trichosanthes truncata

Author:
I-Ting Weng; Yen-An Lin; Guan-Yu Chen; Hsiu-Mei Chiang; Yi-Jung Liu; Chao-Jung Chen; Yu-Hsuan Lan; Chia-Lin Lee
Source:
Natural product research 2020 v.34 no.16 pp. 2262-2268
ISSN:
1478-6427
Subject:
Trichosanthes; amino acids; anhydrides; antioxidants; binding capacity; bleaching agents; cytotoxicity; electrostatic interactions; enzyme inhibitors; enzymes; hydrogen bonding; inhibitory concentration 50; keratinocytes; mushrooms; skin diseases; spectroscopy
Abstract:
... One new amino acid derivative, (–)-β-homoarginine anhydride 1, as well as nine known compounds were isolated from Trichosanthes truncata. The structures of the isolates were elucidated by spectroscopic methods. Among them, compounds 5 and 11 could notably dose-dependently inhibit ROS productions in HaCaT keratinocyte cells without cytotoxicity in the concentration range of 0.2–20 μM. In cell-free ...
DOI:
10.1080/14786419.2018.1531404

4. 113 Effect of antioxidants on motility and fertility of liquid-stored bovine sperm

Author:
Y. Honkawa; T. Fujikawa; N. Miura; C. Kubota
Source:
Reproduction, fertility, and development 2020 v.32 no.2 pp. 183-184
ISSN:
1031-3613
Subject:
air; analysis of variance; antioxidants; beta-mercaptoethanol; blastocyst; bulls; egg yolk; embryogenesis; freeze-thaw cycles; frozen storage; glutathione; in vitro fertilization; liquid nitrogen; liquids; oocytes; semen; sperm concentration; sperm motility; spermatozoa
Abstract:
... It is difficult to maintain sperm in liquid storage for a long time, compared with permanent frozen storage in liquid nitrogen. Antioxidants have been reported to improve the quality and fertility of liquid-stored semen. In this study, we investigated whether antioxidants can extend the motility and fertility of frozen-thawed sperm in liquid storage. Frozen-thawed semen from one Japanese black bul ...
DOI:
10.1071/RDv32n2Ab113

5. 1H‐NMR metabolomics profiling of recombinant tobacco plants holding a promoter of a sesquiterpene cyclase

Author:
Elvia Becerra‐Martínez; Yesenia Pacheco‐Hernández; Edmundo Lozoya‐Gloria; Martha G. Betancourt‐Jiménez; Diego Hidalgo‐Martínez; Luis G. Zepeda‐Vallejo; Nemesio Villa‐Ruano
Source:
Phytochemical analysis 2020 v.31 no.4 pp. 480-487
ISSN:
0958-0344
Subject:
Capsicum annuum; Nicotiana tabacum; acetates; antioxidants; bioactive properties; capsidiol; chlorogenic acid; discriminant analysis; ethanol; formates; genes; isomers; metabolites; metabolome; metabolomics; nuclear magnetic resonance spectroscopy; phytoalexins; phytochemicals; principal component analysis; regulatory sequences; tobacco; transgenic plants; trichodiene synthase
Abstract:
... INTRODUCTION: Nicotiana tabacum is a plant model intensively used in the bio‐engineering pharmaceutical industry as a platform to produce drugs and therapeutic agents. Currently, no information regarding the non‐targeted metabolome of transgenic tobacco containing recombinant regulatory sequences is available. OBJECTIVE: To compare the proton nuclear magnetic resonance (¹H‐NMR) metabolomics profil ...
DOI:
10.1002/pca.2911

6. 2-methoxy-isobutyl-isonitrile-conjugated gold nanoparticles improves redox and inflammatory profile in infarcted rats

Author:
Ludimilla Pereira Tartuce; Fábio Pacheco Brandt; Giulia dos Santos Pedroso; Hemelin Rezende Farias; Bruna Barros Fernandes; Bárbara da Costa Pereira; Alessandra Gonçalves Machado; Paulo Emílio Feuser; Paulo Cesar Lock Silveira; Renata Tiscoski Nesi; Marcos Marques da Silva Paula; Michael Andrades; Ricardo Aurino de Pinho
Source:
Colloids and surfaces 2020 v.192 pp. 111012
ISSN:
0927-7765
Subject:
anti-inflammatory agents; antioxidants; cardiotoxicity; echocardiography; heart; histopathology; infarction; inflammation; laboratory animals; liver function; mitochondria; models; myocardial infarction; nanogold; oxidative stress; rats; reperfusion injury; therapeutics
Abstract:
... The tissue response to acute myocardial infarction (AMI) is key to avoiding heart complications due to inflammation, mitochondrial dysfunction, and oxidative stress. Antioxidant and anti-inflammatory agents can minimize the effects of AMI. This study investigated the role of 2-methoxy-isobutyl-isonitrile (MIBI)-associated gold nanoparticles (AuNP) on reperfusion injury after ischemia and its effec ...
DOI:
10.1016/j.colsurfb.2020.111012

7. 20-hydroxyeicosatetraenoic acid alters endothelial cell barrier integrity independent of oxidative stress and cell death

Author:
Vengai Mavangira; Jennifer Brown; Jeffery C. Gandy; Lorraine M. Sordillo
Source:
Prostaglandins and Other Lipid Mediators 2020 v.149 no. pp. -
ISSN:
1098-8823
Subject:
antioxidants; aorta; apoptosis; bovine mastitis; cattle; coliform bacteria; endothelial cells; glutathione; inflammation; metabolites; models; oxidative stress; prostaglandins; selenium; therapeutics; vitamin E
Abstract:
... Unregulated inflammation during bovine mastitis is characterized by severe mammary tissue damage with systemic involvement. Vascular dysfunction underlies tissue pathology because of concurrent oxidative stress mediated by several inflammatory mediators. We recently demonstrated increased production of 20-hydroxyeicosatetraenoic acid (20-HETE), a cytochrome P450-derived (CYP) oxylipid that correla ...
Handle:
10113/7448363
DOI:
10.1016/j.prostaglandins.2020.106425
CHORUS:
10.1016/j.prostaglandins.2020.106425

8. 24-Epibrassinolide combined with heavy metal resistant bacteria enhancing phytoextraction of Amaranthus hypochondriacus L. in Cd-contaminated soil

Author:
Yanluo Xie; Yao Luo; Mingping Sheng; He Peng; Yuanming Gu; Heng Xu; Yun Zhao
Source:
Journal of hazardous materials 2020 v.399 pp. 123031
ISSN:
0304-3894
Subject:
Amaranthus hypochondriacus; Serratia; antioxidants; bacteria; beta-fructofuranosidase; bioavailability; community structure; enzyme activity; heavy metals; metal tolerance; microbial communities; phosphates; phytoaccumulation; plant growth; plant hormones; polluted soils; soil pH; urease
Abstract:
... The remediation efficiency of phytoextraction on heavy metal could be influenced by metal bioavailability and plant growth. Hence, we applied a synergistic intensification system with plant hormone (24-Epibrassinolide, EBR) and metal-resistant bacterium (Serratia sp. CTZ4) to enhance Cd extraction of Amaranthus hypochondriacus L. in contaminated soil. Results demonstrated that the combination of C ...
DOI:
10.1016/j.jhazmat.2020.123031

9. 24-epibrassinolide induces protection against waterlogging and alleviates impacts on the root structures, photosynthetic machinery and biomass in soybean

Author:
Ynglety Cascaes Pereira; Fernanda Rodrigues da Silva; Breno Ricardo Serrão da Silva; Flávio José Rodrigues Cruz; Douglas José Marques; Allan Klynger da Silva Lobato
Source:
Plant signaling & behavior 2020 v.15 no.11 pp. 1805885
ISSN:
1559-2324
Subject:
antioxidants; behavior; biodegradability; biomass; chlorophyll; chloroplasts; electron transfer; gas exchange; nutrient uptake; soybeans
Abstract:
... Plants exhibit several restrictions under waterlogging conditions, including stomatal limitations, negative impacts on gas exchange, lower nutrient uptake and reduced growth. 24-epibrassinolide (EBR) is a polyhydroxylated steroid, with the advantages to be a natural and biodegradable molecule, presenting beneficial roles in metabolic and physiological processes. The aim of this research is to inve ...
DOI:
10.1080/15592324.2020.1805885

10. 26 Baobab oil supplemented extender preserves post-thaw bull sperm quality parameters

Author:
Z. Raphalalani; F. Ramukhithi; R. Ndhlala; K. Nephawe; T. Nedambale
Source:
Reproduction, fertility, and development 2020 v.32 no.2 pp. 139
ISSN:
1031-3613
Subject:
Adansonia digitata; DNA; DNA damage; analysis of variance; antioxidant activity; antioxidants; bulls; cryopreservation; freezers; frozen storage; liquid nitrogen; nucleotidyltransferases; oils; oxidative stress; plant extracts; semen extenders; seminal plasma; sperm motility; sperm quality; straw; thawing; viability
Abstract:
... The processes of semen cryopreservation and thawing affect sperm membrane integrity and motility and increases morphological defects as well as DNA damage. The most influential cause of this is oxidative stress. When endogenous antioxidant capacity of seminal plasma is reduced during the freeze-thawing process, plant extracts exhibiting strong antioxidant activity can be used as supplements for co ...
DOI:
10.1071/RDv32n2Ab26

11. 3D Culture Models with CRISPR Screens Reveal Hyperactive NRF2 as a Prerequisite for Spheroid Formation via Regulation of Proliferation and Ferroptosis

Author:
Nobuaki Takahashi; Patricia Cho; Laura M. Selfors; Hendrik J. Kuiken; Roma Kaul; Takuro Fujiwara; Isaac S. Harris; Tian Zhang; Steven P. Gygi; Joan S. Brugge
Source:
Molecular cell 2020 v.80 no.5 pp. 828-844.e6
ISSN:
1097-2765
Subject:
CRISPR-Cas systems; antioxidants; death; ferroptosis; lipids; lung neoplasms; mammals; oxidants; pathogenesis; peroxidase; proteomics; rapamycin; selenoproteins; transcription factors
Abstract:
... Cancer-associated mutations that stabilize NRF2, an oxidant defense transcription factor, are predicted to promote tumor development. Here, utilizing 3D cancer spheroid models coupled with CRISPR-Cas9 screens, we investigate the molecular pathogenesis mediated by NRF2 hyperactivation. NRF2 hyperactivation was necessary for proliferation and survival in lung tumor spheroids. Antioxidant treatment r ...
DOI:
10.1016/j.molcel.2020.10.010

12. 3D printed functional cookies fortified with Arthrospira platensis: Evaluation of its antioxidant potential and physical-chemical characterization

Author:
Marta V. Vieira; Sara M. Oliveira; Isabel R. Amado; Luiz H. Fasolin; Antonio A. Vicente; Lorenzo M. Pastrana; Pablo Fuciños
Source:
Food hydrocolloids 2020 v.107 pp. 105893
ISSN:
0268-005X
Subject:
Arthrospira platensis; alginates; antioxidant activity; antioxidants; baking; bioactive compounds; biomass; color; cookies; dough; encapsulation; ethanol; experimental design; freeze drying; functional foods; heat; hydrocolloids; ingredients; microalgae; microbeads; models; nutrients; nutrition; oxygen; solvents; storage time; texture; three-dimensional printing; ultrasonic treatment
Abstract:
... In the last few decades, consumers' growing attention to the close relationship between health and nutrition is emerging as a new trend, mostly regarding the incorporation of natural ingredients into food. Among those ingredients, microalgae are considered as innovative and promising compounds, rich in valuable nutrients and bioactive molecules. In the present work, 3D printed cookies were fortifi ...
DOI:
10.1016/j.foodhyd.2020.105893

13. 4-Methyl-7-Amino/Amido Coumarin Derivatives as Potential Antimicrobials and Antioxidants

Author:
Muthipeedika Nibin Joy; Yadav D. Bodke; Sandeep Telkar
Source:
Chemistry of natural compounds 2020 v.56 no.4 pp. 614-620
ISSN:
0009-3130
Subject:
antibacterial properties; antifungal properties; antioxidant activity; antioxidants; ciprofloxacin; computer simulation; coumarin; enzymes; fluconazole; hydrogen; hydrophobicity
Abstract:
... An array of previously synthesized 4-methyl-7-amino and amido coumarins 4a–u has been screened for their antimicrobial and antioxidant properties. Some of the compounds exhibited promising antibacterial and antifungal activities (MIC ranging from 4–64 μg/mL) when compared to the respective standards. Compound 4u showed comparable antibacterial activity with the standard, ciprofloxacin, whereas com ...
DOI:
10.1007/s10600-020-03106-y

14. 5-cis-, Trans- and Total Lycopene Plasma Concentrations Inversely Relate to Atherosclerotic Plaque Burden in Newly Diagnosed Type 2 Diabetes Subjects

Author:
Gemma Chiva-Blanch; Claudia Jiménez; Montserrat Pinyol; Zoe Herreras; Marta Catalán; Miriam Martínez-Huélamo; Rosa M Lamuela-Raventos; Aleix Sala-Vila; Montserrat Cofán; Rosa Gilabert; Amanda Jiménez; Emilio Ortega
Source:
Nutrients 2020 v.12 no.6 pp. -
ISSN:
2072-6643
Subject:
antioxidants; atherosclerosis; cross-sectional studies; hyperglycemia; hyperlipidemia; inflammation; insulin resistance; liquid chromatography; lycopene; mass spectrometry; noninsulin-dependent diabetes mellitus; oxidative stress; population; risk; soil; thickness; tomatoes
Abstract:
... Diabetic subjects are at increased risk of cardiovascular disease. Atherosclerosis, the common soil of most of the cardiovascular complications, is more prevalent and extensive in this population due not only to hyperglycemia, insulin resistance, and dyslipidemia, but also to inflammation and oxidative stress. Lycopenes are bioactive compounds with antioxidant and anti-inflammatory activities most ...
DOI:
10.3390/nu12061696

15. 6-Gingerol delays tumorigenesis in benzo[a]pyrene and dextran sulphate sodium-induced colorectal cancer in mice

Author:
Ebenezer O. Farombi; Babajide O. Ajayi; Isaac A. Adedara
Source:
Food and chemical toxicology 2020 v.142 pp. 111483
ISSN:
0278-6915
Subject:
angiogenesis; angiopoietin-1; antioxidants; apoptosis; carcinogenesis; chemoprevention; colon; colorectal neoplasms; corn oil; cyclins; dextran; ginger; sodium; sulfates; toxicology; wnt proteins
Abstract:
... Colorectal cancer (CRC) has been linked to dietary consumption of benzo[a]pyrene (B[a]P). 6-Gingerol (6-G), a component of ginger has been reported to possess anti-inflammatory and antioxidant activities, but little is known regarding the mechanism of 6-G in CRC chemoprevention. We therefore investigated the effect of 6-G on B[a]P. and dextran sulphate sodium (DSS) induced CRC in mice. Mice in Gro ...
DOI:
10.1016/j.fct.2020.111483

16. 70 Trolox during invitro maturation of bovine oocytes protects developing embryos from palmitic acid-induced lipotoxicity

Author:
J. De Bie; W. Marei; P. Bols; J. Leroy
Source:
Reproduction, fertility, and development 2020 v.32 no.2 pp. 161
ISSN:
1031-3613
Subject:
analysis of variance; antioxidant activity; antioxidants; blastocyst; cattle; embryogenesis; ethanol; in vitro culture; lipotoxicity; membrane potential; mitochondria; mitochondrial membrane; oocytes; oxidative stress; palmitic acid; protective effect; solvents; vitamin E; water-soluble vitamins; zygote
Abstract:
... Maternal metabolic disorders are associated with elevated concentrations of palmitic acid (PA), which is known to jeopardize bovine oocyte and embryo development and quality. Analyses of PA-exposed bovine oocytes and embryos point toward oxidative stress (OS)-related pathways. Previous research has shown that the detrimental effects of PA exposure during oocyte IVM cannot be alleviated by antioxid ...
DOI:
10.1071/RDv32n2Ab70

17. Bacillus subtilis Fermentation of Malva verticillata Leaves Enhances Antioxidant Activity and Osteoblast Differentiation

Author:
Keumok Moon; Seola Lee; Jaeho Cha
Source:
Foods 2020 v.9 no.5 pp. -
ISSN:
2304-8158
Subject:
Bacillus subtilis; Malva verticillata; alkaline phosphatase; antioxidant activity; antioxidants; fermentation; flavonoids; gene expression; herbaceous plants; medicine; mitogen-activated protein kinase; osteoblasts; phosphorylation; transcription factors
Abstract:
... Malva verticillata, also known as Chinese mallow, is an herbaceous plant with colorful flowers and has been used as a medicine for thousands of years. This study investigated this herb for potential antioxidant activity or an association with osteoblast differentiation. M. verticillate leaves were fermented with B. subtilis MV1 at 30 °C for 7 days to enhance their biologic ...
DOI:
10.3390/foods9050671

18. Citrus × Clementina Hort. Juice Enriched with Its By-Products (Peels and Leaves): Chemical Composition, In Vitro Bioactivity, and Impact of Processing

Author:
Mariarosaria Leporini; Monica Rosa Loizzo; Vincenzo Sicari; Teresa Maria Pellicanò; Antonella Reitano; Annabelle Dugay; Brigitte Deguin; Rosa Tundis
Source:
Antioxidants 2020 v.9 no.4 pp. -
ISSN:
2076-3921
Subject:
Citrus; antioxidant activity; antioxidants; ethanol; juices; leaves; maceration; models; noninsulin-dependent diabetes mellitus; obesity; oxidative stress; pasteurization; phytochemicals; sensory evaluation; ultrasonic treatment; Italy
Abstract:
... This work investigated a model for the reuse of Citrus × clementina Hort. by-products for the development of a functional drink able to exert antioxidant, hypoglycaemic, and hypolipidemic effects. Juice obtained from fruits collected in three different areas of Calabria (Italy) was analysed. C. × clementina juice from Corigliano Calabro (JF), characterized by the highest ...
DOI:
10.3390/antiox9040298

19. Citrus Essential Oils (CEOs) and Their Applications in Food: An Overview

Author:
Himashree Bora; Madhu Kamle; Dipendra Kumar Mahato; Pragya Tiwari; Pradeep Kumar
Source:
Plants 2020 v.9 no.3 pp. -
ISSN:
2223-7747
Subject:
Citrus; aldehydes; antimicrobial properties; antioxidants; bioactive compounds; cost effectiveness; essential oils; food matrix; food safety; linalool; packaging; packaging materials; preservatives; sabinene; sesquiterpenoids
Abstract:
... Citrus is a genus belonging to the Rutaceae family and includes important crops like orange, lemons, pummelos, grapefruits, limes, etc. Citrus essential oils (CEOs) consist of some major biologically active compounds like α-/β-pinene, sabinene, β-myrcene, d-limonene, linalool, α-humulene, and α-terpineol belonging ...
DOI:
10.3390/plants9030357

20. Citrus Flavones: An Update on Sources, Biological Functions, and Health Promoting Properties

Author:
Davide Barreca; Giuseppina Mandalari; Antonella Calderaro; Antonella Smeriglio; Domenico Trombetta; Maria Rosa Felice; Giuseppe Gattuso
Source:
Plants 2020 v.9 no.3 pp. -
ISSN:
2223-7747
Subject:
Citrus; antineoplastic activity; antioxidants; apigenin; bioavailability; databases; enzymes; fruits; glycosides; health promotion; human nutrition; juices; luteolin; nutrients
Abstract:
... Citrus spp. are among the most widespread plants cultivated worldwide and every year millions of tons of fruit, juices, or processed compounds are produced and consumed, representing one of the main sources of nutrients in human diet. Among these, the flavonoids play a key role in providing a wide range of health beneficial effects. Apigenin, diosmetin, luteolin, acacetin, chrysoeriol, and ...
DOI:
10.3390/plants9030288