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You searched for: Subject "serine C-palmitoyltransferase" Remove constraint Subject: "serine C-palmitoyltransferase" Publication Year 2020 Remove constraint Publication Year: 2020 Subject curcumin Remove constraint Subject: curcumin Subject ceramides Remove constraint Subject: ceramides Text Availability Citation in PubAg Remove constraint Text Availability: Citation in PubAg
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1. Curcumin stimulates exosome/microvesicle release in an in vitro model of intracellular lipid accumulation by increasing ceramide synthesis

Author:
García-Seisdedos, David; Babiy, Bohdan; Lerma, Milagros; Casado, María E.; Martínez-Botas, Javier; Lasunción, Miguel A.; Pastor, Óscar; Busto, Rebeca
Source:
Biochimica et biophysica acta 2020 v.1865 no.5 pp. 158638
ISSN:
1388-1981
Subject:
serine C-palmitoyltransferase,   etc   ; Curcuma longa; animal models; ceramides; curcumin; enzyme inhibitors; exosomes; fumonisin B1; hydrophobicity; mice; neuroglia; polyphenols; rhizomes; secretion; sphingosine N-acyltransferase;     Show all 15 Subjects
Abstract:
... Curcumin, a hydrophobic polyphenol found in the rhizome of Curcuma longa, has been shown to reduce intracellular lipid accumulation in mouse models of lysosomal storage diseases such as Niemann-Pick type C. Exosomes are small extracellular vesicles secreted by cells in response to changes in intracellular ceramide composition. Curcumin can induce exosome/microvesicle release in cellular models of ...
DOI:
10.1016/j.bbalip.2020.158638